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L-Lactic dehydrogenase

Product Name
L-Lactic dehydrogenase
CAS No.
9001-60-9
Chemical Name
L-Lactic dehydrogenase
Synonyms
LD;LAD;LDH;MFH1;MFI7;L-LDH;FOXC2;MFH-1;LCAMB;FKHL14
CBNumber
CB0304186
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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L-Lactic dehydrogenase Property

storage temp. 
2-8°C
solubility 
aqueous buffer: soluble
form 
suspension
color 
white
PH
7.5
biological source
rabbit muscle
Water Solubility 
low ionic strength buffer: soluble
water: soluble
Merck 
13,5349
Specific Activity
800-1,200units/mg protein
CAS DataBase Reference
9001-60-9
EPA Substance Registry System
Dehydrogenase, lactate (9001-60-9)
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Safety

Risk Statements 
21/22-36/37/38
Safety Statements 
22-24/25-36/37-26
WGK Germany 
3
F 
3-10
HS Code 
35079090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB1412479
Product name
ANTI-FOXC2 antibody produced in mouse
Purity
clone 1D4, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$541
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB1412346
Product name
ANTI-FOXC2 antibody produced in mouse
Purity
clone 4A3, purified immunoglobulin, buffered aqueous solution
Packaging
100μG
Price
$541
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB1412345
Product name
ANTI-FOXC2 antibody produced in mouse
Purity
clone 4A5, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$541
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB1412344
Product name
ANTI-FOXC2 antibody produced in mouse
Purity
clone 3E6, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$541
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB1412343
Product name
ANTI-FOXC2 antibody produced in mouse
Purity
clone 3H5, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$541
Updated
2025/07/31
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L-Lactic dehydrogenase Chemical Properties,Usage,Production

Chemical Properties

Off-white lyophilized powder or crystalline suspension of 3.2 mol/L ammonium sulfate, soluble in water, pI of 4.6, optimum pH 6.0.Stability: crystalline enzyme solution can be stored for 6-8 weeks with unchanged activity, sulfate suspension can be stabilized for more than a year, very dilute solution is unstable; optimum temperature of 39 ℃, rapid inactivation of temperatures above 60 ℃. Inhibitors are excess pyruvate, excess NAD, oxalic acid, oxalic acid monoamide, hydroxymalonic acid, malonic acid, urea, Cu2+, Hg2+, Ag+, 4-chloromercuric benzoic acid, pyrophosphoric acid or phosphate buffer and non-competitive inhibitors formed from coenzyme I (NAD) in alkaline inhibit oxidation reaction, excess lactate and non-competitive inhibitors formed from reduced coenzyme I (NADH) inhibit reduction reaction. inhibitors inhibit the reduction reaction; activators are 2-amino-2-methyl-1-propanol, fluoride, diethanolamine, and heparin (oxidizing). Enzymatic reaction: pyruvate + reduced coenzyme I + H+ ═ lactate + coenzyme I.

Uses

L-Lactic Dehydrogenase from bovine heart has been used in ATPase assay of R2 complex Rvb1p-Rvb2p, RecA protein and sarcoplasmic reticulum Ca2+-ATPase (SERCA).

Uses

L-Lactic dehydrogenase is used in the determination of pyruvate (used in conjunction with reduced coenzyme) and in the diagnosis of myocardial infarction and leukemia.

Uses

L-Lactic Dehydrogenase from bovine heart has been used as a standard in cytotoxicity assay. It has also been used in glutamic pyruvic transaminase (GPT) assay.

General Description

L-lactate dehydrogenase (LDH) is an enzyme that catalyzes the conversion of lactate to pyruvate.?In particular, lactic dehydrogenase A (LDHA) is mainly found in skeletal muscle, and for that reason is known as the M subunit. This recombinant form of LDHA has a C-terminal histidine-tag.
The gene LDHA (L-lactate dehydrogenase A chain) is mapped to human chromosome 11p15. It is a subunit of lactate dehydrogenase.

Biochem/physiol Actions

Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids.

Purification Methods

A forty-fold purification of the dehydrogenase is effected by affinity chromatography using Sepharose 4B coupled to 8-(6-aminohexyl)amino-5'-AMP or -NAD . [Lees et al. Arch Biochem Biophys 163 561 1974, Pesce et al. J Biol Chem 239 1753 1964.]

L-Lactic dehydrogenase Preparation Products And Raw materials

Raw materials

Calcium phosphate

Preparation Products

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L-Lactic dehydrogenase Suppliers

China 232 Europe 2 France 1 Germany 8 India 6 Japan 4 Switzerland 1 United Kingdom 3 United States 22 Global 279
Mitsubishi Chemical Europe GmbH
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info@mc-e.de
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Germany
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Sinus Biochemistry & Electrophoresis GmbH
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m.demharter@sinus-biochem.de
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Germany
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AppliChem GmbH
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service@applichem.de
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Germany
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SERVA Electrophoresis GmbH
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Country
Germany
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Service Chemical Inc.
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sales@chemos-group.com
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Germany
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6350
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AppliChem GmbH
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service@applichem.de
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Germany
ProdList
1607
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Julich Chiral Solutions
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Germany
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BIOTREND Chemikalien GmbH
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jaeger@biotrend.com
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Germany
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View Lastest Price from L-Lactic dehydrogenase manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-Lactic dehydrogenase 9001-60-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-27
Hebei Fengjia New Material Co., Ltd
Product
LACTATE DEHYDROGENASE 9001-60-9
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-09-09
Shaanxi Dideu Medichem Co. Ltd
Product
L-Lactic dehydrogenase 9001-60-9
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-08-30

9001-60-9, L-Lactic dehydrogenaseRelated Search:

Lactic acid Ethyl isocyanoacetate Tris(2,4-pentanedionato)chroMiuM(III) COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE PHENYLSELENOL DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) N-BUTYLISOCYANIDE Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Benzyl isocyanide SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TERT-BUTYL ISOCYANIDE Tosylmethyl isocyanide Cupric acetylacetonate EC 1.1.1.28

  • IUB: 1.1.1.27
  • LACTIC DEHYDROGENASE
  • LACTIC DEHYDROGENASE BOVINE HEART
  • LACTIC ACID DEHYDROGENASE
  • LACTATE DEHYDROGENASE
  • LACTATE DEHYDROGENASE, HUMAN MUSCLE
  • LACTATE DEHYDROGENASE ISOENZYME-1, HUMAN
  • L-LACTATE DEHYDROGENASE
  • L-LACTATE DEHYDROGENASE CH
  • L-LACTATE DEHYDROGENASE RM
  • L-LACTATE: NAD OXIDOREDUCTASE
  • L-LACTATE: NAD+ OXIDOREDUCTASE
  • L-LACTIC DEHYDROGENASE
  • L-LACTIC DEHYDROGENASE TYPE I
  • L-LACTIC DEHYDROGENASE TYPE II
  • L-LACTIC DEHYDROGENASE TYPE III
  • L-LACTIC DEHYDROGENASE TYPE VIII
  • L-LACTIC DEHYDROGENASE TYPE V-S
  • L-LACTIC DEHYDROGENASE TYPE X
  • L-LACTIC DEHYDROGENASE TYPE XI
  • L-LACTIC DEHYDROGENASE TYPE XVII
  • L-LACTIC DEHYDROGENASE TYPE XXXIX
  • L-LDH
  • L-LDH TYPE I
  • L-LDH TYPE II
  • L-LDH TYPE III
  • L-LDH TYPE VIII
  • L-LDH TYPE V-S
  • L-LDH TYPE X
  • L-LDH TYPE XI
  • L-LDH TYPE XVII
  • L-LDH TYPE XXXIX
  • L-(+)-Lactate Dehydrogenase, (Chicken Heart, recombinant)
  • L-(+)-Lactate Dehydrogenase, (Rabbit Muscle, recombinant)
  • L-Lactate Dehydrogenase 001
  • L-Lactic Dehydrogenase from porcine heart,(S)-Lactate: NAD+ oxidoreductase, L-LDH, LAD, LD
  • L-Lactic Dehydrogenase from trout muscle,(S)-Lactate: NAD+ oxidoreductase, L-LDH, LAD, LD
  • L-Lactic dehydrogena
  • L-Lactic Dehydrogenase [>=400 units/mg]
  • NAD+ OXIDOREDUCTASE TYPE I
  • NAD+ OXIDOREDUCTASE TYPE II
  • NAD+ OXIDOREDUCTASE TYPE V-S
  • NAD+ OXIDOREDUCTASE TYPE XI
  • NAD+ OXIDOREDUCTASE TYPE XXXIX
  • (S) - LACTATE : NAD+ OXIDOREDUCTASE
  • [S]-LACTATE: NAD+ OXIDOREDUCTASE TYPE III
  • [S]-LACTATE: NAD+ OXIDOREDUCTASE TYPE VIII
  • [S]-LACTATE: NAD+ OXIDOREDUCTASE TYPE X
  • [S]-LACTATE: NAD+ OXIDOREDUCTASE TYPE XVII
  • (S)-LACTATE: NAD+ OXIDOREUCTASE
  • L-LACTIC DEHYDROGENASE FROM BACILLUS &
  • L-LACTIC DEHYDROGENASE TYPE XXII*FROM PI GEON BREAST
  • L-LACTIC DEHYDROGENASE TYPE XXVI*FROM BO VINE MUSCLE
  • L-LACTIC DEHYDROGENASE TYPE II FROM*RABB IT MUSCLE C
  • L-LACTIC DEHYDROGENASE BACILLUS STEAROTH ERMOPHILUS
  • LACTATE DEHYDROGENASE FROM BOVINE HEART CRYST.SUSP.~250U/MG*
  • L-LACTIC DEHYDROGENASE TYPE X*FROM BOVIN E MUSCLE
  • L-LACTIC DEHYDROGENASE TYPE IX*FROM BOVI NE HEART