Acid-PEG5-NHS ester

Product Name: Acid-PEG5-NHS ester
CAS No.: 1343476-41-4
Chemical Name: Acid-PEG5-NHS ester
Synonyms: COOH-PEG5-SPA;COOH-PEG5-NHS;Acid-PEG5-NHS ester;COOH-PEG5-NHS ester;Acid-dPEG??-NHS ester;Acid-C2-PEG4-C2-NHS ester;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester;19-((2,5-dioxopyrrolidin-1-yl)oxy)-19-oxo-4,7,10,13,16-pentaoxanonadecanoic acid;19-[(2,5-Dioxopyrrolidin-1-yl)oxy]-19-oxo-4,7,10,13,16-pentaoxanonadecan-1-oic Acid
CBNumber: CB03062294
Molecular Formula: C18H29NO11
Formula Weight: 435.42
MOL File: 1343476-41-4.mol

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Acid-PEG5-NHS ester Property

Boiling point:: 574.8±60.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
form: Liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C384065
Product name: Acid-PEG5-NHSester
Packaging: 10mg
Price: $175
Updated: 2021/12/16

dPEG

Product number: 10109
Product name: Acid-dPEG®₅-NHSester
Packaging: 100mg
Price: $215
Updated: 2021/12/16

dPEG

Product number: 10140
Product name: Acid-dPEG®₂₅-NHSester
Packaging: 100mg
Price: $300
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1000
Product name: Acid-PEG5-NHS ester
Packaging: 100mg
Price: $671
Updated: 2021/12/16

BroadPharm

Product number: BP-22220
Product name: Acid-PEG5-NHSester
Purity: 95%
Packaging: 500mg
Price: $980
Updated: 2021/12/16

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Acid-PEG5-NHS ester Chemical Properties,Usage,Production

Description

Acid-PEG5-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG5-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Acid-PEG5-NHS ester manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Acid-PEG5-NHS ester 1343476-41-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

Xian confluore Biological Technology Co., Ltd.

Product: Acid-PEG5-NHS ester 1343476-41-4
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-03-23

1343476-41-4, Acid-PEG5-NHS esterRelated Search:

Acid-PEG12-NHS ester Acid-PEG4-mono-methyl ester Acid-PEG10-NHS ester Acid-PEG25-NHS ester Acid-PEG4-t-butyl ester Acid-PEG4-Sulfone-PEG4-Acid Acid-PEG3-mono-methyl ester Acid-PEG5-TEMPO Acid-PEG5-mono-methyl ester Acid-PEG5-t-butyl ester

Acid-PEG5-NHS ester

COOH-PEG5-NHS

Acid-C2-PEG4-C2-NHS ester

4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester

COOH-PEG5-SPA

Acid-dPEG??-NHS ester

COOH-PEG5-NHS ester

19-((2,5-dioxopyrrolidin-1-yl)oxy)-19-oxo-4,7,10,13,16-pentaoxanonadecanoic acid

19-[(2,5-Dioxopyrrolidin-1-yl)oxy]-19-oxo-4,7,10,13,16-pentaoxanonadecan-1-oic Acid

1343476-41-4

C18H29NO11

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