ChemicalBook > CAS DataBase List > DBCO-(CH2)3-Acid

DBCO-(CH2)3-Acid

Product Name: DBCO-(CH2)3-Acid
CAS No.: 1207355-31-4
Chemical Name: DBCO-(CH2)3-Acid
Synonyms: DBCO acid 2;DBCO-C3-Acid;DBCO-C5-acid;DBCO-(CH2)3-Acid;CAS_1207355-31-4;DBCO-C3-Acid, 10 mM in DMSO;11,12-Didehydro-δ-oxodibenz[b,f]azocine-5(6H)-pentanoic acid;Dibenz[b,f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-;Dibenz[b,?f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-;5-[11,12-didehydrodibenzo[b,f ]azocin-5(6H)-yl]-5-oxopentanoic acid
CBNumber: CB03358331
Molecular Formula: C20H17NO3
Formula Weight: 319.35
MOL File: 1207355-31-4.mol

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DBCO-(CH2)3-Acid Property

Boiling point:: 635.5±55.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: DMSO : 100 mg/mL (313.14 mM; Need ultrasonic)
pka: 4.63±0.10(Predicted)
form: Solid
color: Off-white to brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

dPEG

Product number: 11814
Product name: DBCO-acid
Packaging: 1000mg
Price: $1300
Updated: 2021/12/16

JR MediChem

Product number: JR6-L6318
Product name: Dibenz[b,f]azocine-5(6H)-pentanoicacid,11,12-didehydro-d-oxo-
Purity: 96%
Packaging: 100mg
Price: $268
Updated: 2021/12/16

JR MediChem

Product number: JR6-L6318
Product name: Dibenz[b,f]azocine-5(6H)-pentanoicacid,11,12-didehydro-d-oxo-
Purity: 96%
Packaging: 500mg
Price: $880
Updated: 2021/12/16

JR MediChem

Product number: JR6-L6318
Product name: Dibenz[b,f]azocine-5(6H)-pentanoicacid,11,12-didehydro-d-oxo-
Purity: 96%
Packaging: 1g
Price: $1280
Updated: 2021/12/16

JR MediChem

Product number: JR6-L6318
Product name: Dibenz[b,f]azocine-5(6H)-pentanoicacid,11,12-didehydro-d-oxo-
Purity: 96%
Packaging: 5g
Price: $3980
Updated: 2021/12/16

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DBCO-(CH2)3-Acid Chemical Properties,Usage,Production

Uses

DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1].

References

[1] van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26(11):2233-2242. DOI:10.1021/acs.bioconjchem.5b00224

DBCO-(CH2)3-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1207355-31-4, DBCO-(CH2)3-AcidRelated Search:

DBCO-Acid DBCO-NH-Boc Cy3 DBCO DBCO-maleimide DBCO-PEG1 Dbco-Amine TFA Cy5 DBCO Azadibenzocyclooctyne-Biotin conjugate Oleic-DBCO DBCO-C-PEG1 DBCO-C6-acid BDP FL DBCO DBCO-(CH2)2-NH2-CO-(CH2)2COOH DBCO-amine DBCO-NHS Ester DBCO-(CH2)2-NH2-CO-(CH2)3COOH

DBCO-C5-acid

CAS_1207355-31-4

DBCO acid 2

DBCO-(CH2)3-Acid

Dibenz[b,f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-

11,12-Didehydro-δ-oxodibenz[b,f]azocine-5(6H)-pentanoic acid

Dibenz[b,?f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-

DBCO-C3-Acid

5-[11,12-didehydrodibenzo[b,f ]azocin-5(6H)-yl]-5-oxopentanoic acid

DBCO C3 Acid,inhibit,Inhibitor,DBCO-C-3-Acid,Antibody-drug conjugates linkers,DBCOC3Acid,ADC Linkers

DBCO-C3-Acid, 10 mM in DMSO

1207355-31-4