ChemicalBook > CAS DataBase List > Acetyl ketene

Acetyl ketene

Product Name: Acetyl ketene
CAS No.: 674-82-8
Chemical Name: Acetyl ketene
Synonyms: DIKETENE;4-Methyleneoxetan-2-one;DK;Diketen;Acety ketene;4-METHYLENE-2-OXETANONE;3-hydroxy-3-butenoicacibeta-lactone;DM2-Sme;Dikitene;ACETYLKETENE
CBNumber: CB0369048
Molecular Formula: C4H4O2
Formula Weight: 84.07
MOL File: 674-82-8.mol

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Acetyl ketene Property

Melting point:: -7.5°C
Boiling point:: 69-70 °C100 mm Hg(lit.)
Density: 1.09 g/mL at 25 °C(lit.)
vapor density: 2.9 (vs air)
vapor pressure: 7.9 mm Hg ( 20 °C)
refractive index: n20/D 1.439(lit.)
Flash point:: 95 °F
storage temp.: 2-8°C
InChI: InChI=1S/C4H4O2/c1-3-2-4(5)6-3/h1-2H2
InChIKey: WASQWSOJHCZDFK-UHFFFAOYSA-N
SMILES: O1C(=C)CC1=O
CAS DataBase Reference: 674-82-8(CAS DataBase Reference)
NIST Chemistry Reference: 2-Oxetanone, 4-methylene-(674-82-8)
EPA Substance Registry System: Diketene (674-82-8)

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Safety

Hazard Codes: Xn
Risk Statements: 10-20-40-36/37/38
Safety Statements: 3-36/37-33-24/25-23-16-26
RIDADR: UN 2929 6.1/PG 2
WGK Germany: 2
RTECS: RQ8225000
F: 19-21-27
HazardClass: 6.1(a)
PackingGroup: I
Hazardous Substances Data: 674-82-8(Hazardous Substances Data)
IDLA: 7.6 ppm

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FD46168
Product name: Diketene
Packaging: 5G
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD46168
Product name: Diketene
Packaging: 10g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD46168
Product name: Diketene
Packaging: 25g
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD46168
Product name: Diketene
Packaging: 50g
Price: $300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD46168
Product name: Diketene
Packaging: 100g
Price: $590
Updated: 2021/12/16

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Acetyl ketene Chemical Properties,Usage,Production

Chemical Properties

Diketene [674-82-8], C4H4O2, Mr 84.04, is a colorless liquid when pure; it possesses a pungent odor and is a strong lachrymator. The human odor perception threshold is 0.019 mg/m3. Crude diketene obtained from the dimerization of ketene is often used without further purification; it is dark brown and contains up to 10 % higher ketene polymers.

Uses

Diketene is used as a reactant in the manufacture of paper and control of its sizing. In addition its used in the preparation of potent and selective inhibitor of histone methyltransferase EZH2 in the treatment of B-Cell lymphomas.

General Description

A colorless liquid with a disagreeable odor. Slightly less dense than water. Flash point 90°F. Irritates skin and eyes. Used to make paints and pharmaceuticals.

Air & Water Reactions

Highly flammable. Slightly soluble in water.

Reactivity Profile

DIKETENE is a very reactive dimer, Acetyl ketene may undergo a spontaneous decomposition followed by explosion or ignition [Vervalin, 1973, p.86]. In the presence of bases, amines, mineral acids or Lewis acids a violent polymerization will occur, accompanied by gas evolution [Zdenek, F. et al., Czech Pat. 156 584, 1975].

Health Hazard

TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Chemical Reactivity

Diketene is a reactive, versatile compound, which cannot be stored indefinitely, even in the presence of stabilizing agents such as sulfates, borates, or sulfur. On standing for several days or weeks, it turns yellow and then brown. Glass vessels are not recommended for storage because the basicity of glass promotes decomposition: stainless steel or aluminum is preferred. Diketene reactions proceed mainly by ring opening and are highly exothermic. Traces of base or strong acid can lead to violent, almost explosive polymerization, and due care should be exercised when handling diketene.

Solubility in organics

Diketene is miscible with acetic anhydride, with many ketones and esters (e.g., acetone, methyl acetate, ethyl acetate, butyl acetate) with diethyl ether, tetrahydrofuran, chlorinated hydrocarbons, acetonitrile, and toluene. Furthermore, contrary to most literature reports, it is slightly soluble in aliphatic hydrocarbons such as hexane (ca. 12.5 wt % at 23℃), octane, cyclohexane, and methylcyclohexane. It is very slightly soluble in water, in which it decomposes slowly.

Acetyl ketene Preparation Products And Raw materials

Raw materials

Triethyl phosphate Acetone Polymerization inhibitor Polyethylene Butyl acetate Acetic acid ketene

Preparation Products

Dehydroacetic acid Ethyl acetoacetate N,N'-(3,3'-Dimethyl-4,4'-biphenyldiyl)bis(3-oxobutanamide) tert-Butyl acetoacetate Acetoacetanilide FEMA 2510 22(S),23(S)-Homobrassinolide Acesulfame Amitriptyline hydrochloride 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Butyric anhydride Acetoacetamide Sorbic acid 4'-Methoxyacetoacetanilide Ethyl 4-chloroacetoacetate Olaquindox Acetic anhydride Acesulfame potassium N,N-Diethylacetoacetamide 5-CHLORO-6 B,19-EPOXY-5A -ANDROTANE-3,17-DIONE Manidipine Methyl acetoacetate Pigment Red 122 2'-Methylacetoacetanilide Chloroacetyl chloride Dichlorosulfophenyl-3-methylpyrazolone o-Acetoacetaniside PHOSPHAMIDON Seedavay(Uniroyal) 2-Acetylbutyrolactone N-Acetyl-N-(4-chloro-2-nitrophenyl)acetamide N-Methylacetoacetamide 2,6-HEPTANEDIONE Quizalofop-p-ethyl ACETOACETIC ACID N-BUTYL ESTER Imazethapyr Isobutyl acetoacetate 2'-Chloroacetoacetanilide

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View Lastest Price from Acetyl ketene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Acetyl ketene 674-82-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-26

Hebei Chuanghai Biotechnology Co,.LTD

Product: Acetyl ketene 674-82-8
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.8%
Supply Ability: 100tons
Release date: 2024-08-23

Shaanxi Dideu Medichem Co. Ltd

Product: Acetyl ketene 674-82-8
Price: US $580.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 1T
Release date: 2020-07-06

674-82-8, Acetyl keteneRelated Search:

Acetylacetone N-Vinyl-2-pyrrolidone Crospovidone ketene Pyrrole Acetyl chloride Polyethylene Acetyl coenzyme A sodium salt Polyvinylpyrrolidone Divinylbenzene Bicyclo[3.1.0]hexan-3-one 4,4'-Diphenylmethane diisocyanate Methylene Blue 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one 1H-Pyrazole, 5-methoxy-3-methyl-1-phenyl- BISPYRAZOLONE Edaravone Impurity 14 Edaravone Impurity 26

3-buteno-beta-lactone

3-Butenoic acid, 3-hydroxy-, beta-lactone

3-hydroxy-3-butenoicacibeta-lactone

4-methylene-2-oxetanon

Diketen

diketene,inhibited

Ethenone, dimer

ethenone,dimer

Vinylaceto-beta-lactone

Vinylaceto-lactone

Acety ketene

ACETYLKETENE

4-METHYLENE-2-OXETANONE

But-3-en-3-olide

KETENE DIMER

DIKETENE

Ketenedimer,99%

Dikitene

Diketene(DK)

4-Methyleneoxetan-2-one

beta-Methylene-beta-propiolactone

DIKETENE IN DICHLOROMETHANE, 50% STABIL&

DIKETENE, STABILIZED WITH COPPER SULFATE

DIKETENE STAB.

DIKETENE,4-METHYLENE-OXETAN-2-ONE

Ketenedimere

KETENE DIMER ( DIKETENE )

2-OXETANONE,4-METHYLENE-

DIKETENE, STABILISED

diketene diketen

Diketene (stabilized with Ethylene Glycol)

4-Methylidenoxetan-2-one

1-Butene-1,3-dione

Acetylketene Ketene Dimer 4-Methylene-2-oxetanone

Acetylketene (stabilized with Ethylene Glycol)

But-1-ene-1,3-dione

Acetyl Ketene,>97%

Acetamide,N-[5-(aminosulfonyl)phenyl]-

DM2-Sme

674-82-8

357477-99-6

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