ChemicalBook > CAS DataBase List > Cyclicdimethylpolysiloxane

Cyclicdimethylpolysiloxane

Product Name
Cyclicdimethylpolysiloxane
CAS No.
69430-24-6
Chemical Name
Cyclicdimethylpolysiloxane
Synonyms
POLYDIMETHYLCYCLOSILOXANE;kf993;UP 1004;q2-1401;sws-f222;sws03314;X 2-1401;dowcorning344;Silwet FZ 2166;Silicone TSA 405A
CBNumber
CB0500393
Formula Weight
0
MOL File
Mol file
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Cyclicdimethylpolysiloxane Property

EPA Substance Registry System
Cyclomethicone (69430-24-6)
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Safety

RIDADR 
1993
HazardClass 
3.2
PackingGroup 
III
Hazardous Substances Data
69430-24-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H361Suspected of damaging fertility or the unborn child

H412Harmful to aquatic life with long lasting effects

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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Cyclicdimethylpolysiloxane Chemical Properties,Usage,Production

Chemical Properties

Cyclomethicone occurs as a clear, colorless and tasteless volatile liquid.

Uses

Pharmaceutic aid (wetting agent).

Production Methods

Cyclomethicone is manufactured by the distillation of crude polydimethylsiloxanes.

brand name

VS-7158 (Witco); VS-7207 (Witco); VS-7349 (Witco).

Pharmaceutical Applications

Cyclomethicone is mainly used in topical pharmaceutical and cosmetic formulations such as water-in-oil creams.
Cyclomethicone has been used in cosmetic formulations, at concentrations of 0.1-50%, since the late 1970s and is now the most widely used silicone in the cosmetics industry. Its high volatility, and mild solvent properties, make it ideal for use in topical formulations because its low heat of vaporization means that when applied to skin it has a ‘dry’ feel.

Safety

Cyclomethicone is generally regarded as a relatively nontoxic and nonirritant material. Although it has been used in oral pharmaceutical applications, cyclomethicone is mainly used in topical pharmaceutical formulations. It is also widely used in cosmetics. Studies of the animal and human toxicology of cyclomethicone suggest that it is nonirritant and not absorbed through the skin. Only small amounts are absorbed orally; an acute oral dose in rats produced no deaths.

storage

Cyclomethicone should be stored in an airtight container in a cool, dry, place.

Regulatory Status

Included in the FDA Inactive Ingredients Database(oral powderfor reconstitution, topical lotion, topical cream, topical emulsion). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Cyclicdimethylpolysiloxane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cyclicdimethylpolysiloxane manufacturers

Hebei Guanlang Biotechnology Co,.LTD
Product
Cyclodimethylsiloxanes 69430-24-6
Price
US $10.70/Kg/Drum
Min. Order
10g
Purity
99%
Supply Ability
10000kg
Release date
2021-08-03
Hebei Guanlang Biotechnology Co., Ltd.
Product
DMC 69430-24-6
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2021-01-19
Career Henan Chemical Co
Product
CYCLOMETHICONE 4 (200 MG) 69430-24-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

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