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Thalidomide-O-amido-C3-NH2 (TFA)

Product Name
Thalidomide-O-amido-C3-NH2 (TFA)
CAS No.
2022182-58-5
Chemical Name
Thalidomide-O-amido-C3-NH2 (TFA)
Synonyms
Thalidomide-O-amido-C3-NH2;Thalidomide-O-amido-C3-NH2 (TFA);Cereblon Ligand-Linker Conjugates 16 TFA;Pomalidomide Related Compound 3 Triflate;E3 Ligase Ligand-Linker Conjugates 52 (TFA);N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide(TFA);N-(3-Aminopropyl)-2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]oxy]acetamide Trifluoroacetate;N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate;N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetic acid salt
CBNumber
CB05574524
Molecular Formula
C20H21F3N4O8
Formula Weight
502.4
MOL File
2022182-58-5.mol
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Thalidomide-O-amido-C3-NH2 (TFA) Property

storage temp. 
2-8°C, sealed storage, away from moisture
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC26123
Product name
Thalidomide-O-amido-C3-NH2
Purity
>98%
Packaging
250mg
Price
$700
Updated
2021/12/16
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Thalidomide-O-amido-C3-NH2 (TFA) Chemical Properties,Usage,Production

Uses

Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

IC 50

Cereblon

References

[1] Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. DOI:10.1016/j.bmcl.2016.09.048

Thalidomide-O-amido-C3-NH2 (TFA) Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-amido-C3-NH2 (TFA) Suppliers

China 33 India 1 United States 4 Global 38
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
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Fax
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Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

2022182-58-5, Thalidomide-O-amido-C3-NH2 (TFA)Related Search:

N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate E3 ligase Ligand-Linker Conjugates 17 E3 ligase Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 5 Free Base 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

  • Thalidomide-O-amido-C3-NH2 (TFA)
  • E3 Ligase Ligand-Linker Conjugates 52 (TFA)
  • Thalidomide-O-amido-C3-NH2
  • Pomalidomide Related Compound 3 Triflate
  • N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetic acid salt
  • N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
  • N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide(TFA)
  • N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
  • Cereblon Ligand-Linker Conjugates 16 TFA
  • Inhibitor,E3 Ligase Ligand-Linker Conjugates 52,E3 Ligase Ligand-Linker Conjugates,Cereblon Ligand-Linker Conjugates 16,ThalidomideOamidoC3NH2 TFA,Thalidomide O amido C3 NH2 TFA,Thalidomide-O-amido-C-3-NH2 TFA,inhibit
  • N-(3-Aminopropyl)-2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]oxy]acetamide Trifluoroacetate
  • 2022182-58-5