ChemicalBook > CAS DataBase List > 1H-Benzimidazole-2-methanol

1H-Benzimidazole-2-methanol

Product Name
1H-Benzimidazole-2-methanol
CAS No.
4856-97-7
Chemical Name
1H-Benzimidazole-2-methanol
Synonyms
IFLAB-BB F0266-0027;TIMTEC-BB SBB004085;2-HYDROXYBENXIMIDAZOLE;2-BENZIMIDAZOLEMETHANOL;BENZIMIDAZOLE-2-METHANOL;(2-Benzimidazolyl)methanol;1H-benzimidazol-2-methanol;1H-BENZIMIDAZOLE-2-METHANOL;1H-BENZIMIDAZOL-2-YLMETHANOL;2-HYDROXYMETHYLBENZIMIDAZOLE
CBNumber
CB0666493
Molecular Formula
C8H8N2O
Formula Weight
148.16
MOL File
4856-97-7.mol
More
Less

1H-Benzimidazole-2-methanol Property

Melting point:
171-175 °C (lit.)
Boiling point:
268.75°C (rough estimate)
Density 
1.1828 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
11.57±0.10(Predicted)
form 
Crystalline Powder
color 
Off-white to light brown
InChI
InChI=1S/C8H8N2O/c11-5-8-9-6-3-1-2-4-7(6)10-8/h1-4,11H,5H2,(H,9,10)
InChIKey
IAJLTMBBAVVMQO-UHFFFAOYSA-N
SMILES
C1(CO)NC2=CC=CC=C2N=1
CAS DataBase Reference
4856-97-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36-36/37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
158356
Product name
2-Benzimidazolemethanol
Purity
97%
Packaging
5g
Price
$103
Updated
2025/07/31
Sigma-Aldrich
Product number
158356
Product name
2-Benzimidazolemethanol
Purity
97%
Packaging
1g
Price
$39.8
Updated
2023/06/20
TCI Chemical
Product number
H1229
Product name
2-(Hydroxymethyl)benzimidazole
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$137
Updated
2025/07/31
TRC
Product number
B204065
Product name
(1H-Benzoimidazol-2-yl)methanol
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
B204065
Product name
(1H-Benzoimidazol-2-yl)methanol
Packaging
100mg
Price
$60
Updated
2021/12/16
More
Less

1H-Benzimidazole-2-methanol Chemical Properties,Usage,Production

Chemical Properties

Off-white to light brown crystalline powder

Uses

2-Benzimidazolemethanol was used in the preparation of 2-(chloromethyl)-1-(methylsulfonyl)benzimidazole via methanesulfonylation. It was also used in the synthesis of 1H-benzimidazol-2-ylmethyl diethyl phosphate.

Synthesis

79-14-1

95-54-5

4856-97-7

The compound was prepared based on known methods with some modifications [19,20]. O-phenylenediamine (27 g, 0.25 mol) was dissolved in 500 mL of 4 M HCl, mixed with a solution of ethanoic acid (34.2 g, 0.45 mol) in 250 mL of 4 M HCl, stirred and heated under reflux conditions for 2 hours. Upon completion of the reaction, the reaction mixture was slowly cooled to room temperature and subsequently alkalized to pH neutral with aqueous sodium hydroxide. The precipitated solid was separated by filtration, dried and purified by recrystallization using hot water (Scheme 1). Product I was obtained: white to light brown powder, melting point 171-174 °C, yield 89.1%.

References

[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Bulletin of the Chemical Society of Ethiopia, 2014, vol. 28, # 3, p. 451 - 456
[3] Monatshefte fur Chemie, 2016, vol. 147, # 12, p. 2209 - 2220
[4] Patent: CN106905241, 2017, A. Location in patent: Paragraph 0127-0129
[5] Patent: CN107118249, 2017, A. Location in patent: Paragraph 0117; 0118; 0119

1H-Benzimidazole-2-methanol Preparation Products And Raw materials

Raw materials

Glycolic acid o-Phenylenediamine

Preparation Products

More
Less

1H-Benzimidazole-2-methanol Suppliers

Americas 1 Belgium 2 Canada 1 China 174 Europe 3 France 1 Germany 7 India 12 Japan 3 Russia 2 Slovakia 2 South Korea 1 Switzerland 3 Ukraine 2 United Kingdom 18 United States 31 Global 263
Chengdu Apis Pharmaceutical Technology Co.,Ltd
Tel
13568817957
Fax
028-66535130
Email
dudes@163.com
Country
China
ProdList
300
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai yirong biology science and technology co., ltd
Tel
18049974220
Fax
+86 (21) 51062076
Email
3060526242@qq.com
Country
China
ProdList
995
Advantage
60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2150
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Modachem Shanghai Co., Ltd
Tel
+86 (0)21 51320687 51371369 1744605818
Fax
+86 (0)21 51371369
Country
China
ProdList
1578
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
ShangHai Yuchuan Pharmaceutical Technology Co., Ltd.
Tel
02161555100
Fax
-
Country
China
ProdList
820
Advantage
58
Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2786
Advantage
52
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
More
Less

View Lastest Price from 1H-Benzimidazole-2-methanol manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1H-Benzimidazole-2-methanol 4856-97-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1H-Benzimidazole-2-methanol 4856-97-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
1H-Benzimidazole-2-methanol 4856-97-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

4856-97-7, 1H-Benzimidazole-2-methanolRelated Search:

2-(Cyanomethyl)benzimidazole Trimethylolpropane 2-Phenylbenzimidazole Benzimidazole 2-Chloromethylbenzimidazole 2-Phenylbenzimidazole-5-sulfonic acid Phenformin Methanol 2-Hydroxyethyl methacrylate methylol cellulose 2-Methylbenzimidazole 5-Nitrobenzimidazole 2-GUANIDINOBENZIMIDAZOLE Tris(hydroxymethyl)aminomethane 1H-Benzimidazole-5-methanol,1-methyl-(9CI) 1H-Benzimidazole-5-methanol(9CI) 1H-Benzimidazole-2-methanol,5-methoxy-(9CI),5-METHOXY-1H-BENZIMIDAZOLE-2-METHANOL (1H-IMIDAZOL-2-YL)-METHANOL

  • BENZIMIDAZOLE-2-METHANOL
  • IFLAB-BB F0266-0027
  • 1H-BENZIMIDAZOL-2-YLMETHANOL
  • (1H-BENZOIMIDAZOL-2-YL)-METHANOL
  • 1H-BENZIMIDAZOLE-2-METHANOL
  • 2-(HYDROXYMETHYL)-1H-BENZIMIDAZOLE
  • 1H-BENZIMIDAZOLE-2-METHANOL 97%
  • 2-HYDROXYMETHYLBENZIMIDAZOLE
  • 2-BENZIMIDAZOLEMETHANOL
  • TIMTEC-BB SBB004085
  • 2-(Hydroxymethyl)-1H-benzimidazole 98%
  • 1H-Benzimidazole-2-methanol(9CI)
  • 2-Hydroxymethylbenzimidazole, HPLC 97%
  • 2-HYDROXYBENXIMIDAZOLE
  • (2-Benzimidazolyl)methanol
  • 2-Hydroxymethyl-1H-benzoimidazole
  • 1H-Benzimidazole-2-methanol,97%
  • (1H-benzo[d]imidazol-2-yl)methanol
  • 1H-Benzimidazol-2-ylmethanol, 95%+
  • 1H-benzimidazol-2-methanol
  • 2-Benzimidazolemethanol (2-Benzimidazolyl)methanol
  • 1H-1,3-benzodiazol-2-ylMethanol
  • 2-(Hydroxymethyl)benzimidazole&gt
  • 1H-BENZIMIDAZOLE-2-METHANOL 4856-97-7
  • 4856-97-7
  • 4859-97-7
  • 4856-97-71
  • C8H8N2O
  • Heterocyclic Building Blocks
  • Benzimidazoles
  • Building Blocks
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
  • Heterocycles series
  • Imidazol&Benzimidazole
  • Benzimidazoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Benzimidazole Series
  • BENZIMIDAZOLE
  • Alcohols and Derivatives
  • Heterocycles