2-Amino-5-methylbenzoic acid
- Product Name
- 2-Amino-5-methylbenzoic acid
- CAS No.
- 2941-78-8
- Chemical Name
- 2-Amino-5-methylbenzoic acid
- Synonyms
- 5-METHYLANTHRANILIC ACID;NSC 50786;NSC 39154;Fluralaner-032;2-Amino-5-methyL;BUTTPARK 41\07-01;6-Amino-m-toluylsure;Cetilistat Impurity 6;6-AMINO-M-TOLUIC ACID;OTAVA-BB BB7719100016
- CBNumber
- CB0684541
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 2941-78-8.mol
2-Amino-5-methylbenzoic acid Property
- Melting point:
- 175 °C (dec.) (lit.)
- Boiling point:
- 273.17°C (rough estimate)
- Density
- 1.2023 (rough estimate)
- refractive index
- 1.5810 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Powder
- pka
- 2.27±0.10(Predicted)
- color
- Off-white to beige
- BRN
- 1101527
- InChI
- InChI=1S/C8H9NO2/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H,10,11)
- InChIKey
- NBUUUJWWOARGNW-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(C)=CC=C1N
- CAS DataBase Reference
- 2941-78-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Amino-5-methylbenzoic acid(2941-78-8)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- F
- 10
- HazardClass
- IRRITANT
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 419443
- Product name
- 2-Amino-5-methylbenzoic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $97.9
- Updated
- 2025/07/31
- Product number
- 419443
- Product name
- 2-Amino-5-methylbenzoic acid
- Purity
- 99%
- Packaging
- 25g
- Price
- $462
- Updated
- 2025/07/31
- Product number
- A1421
- Product name
- 2-Amino-5-methylbenzoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- A1421
- Product name
- 2-Amino-5-methylbenzoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $54
- Updated
- 2025/07/31
- Product number
- A614100
- Product name
- 2-Amino-5-methylbenzoic Acid
- Packaging
- 100g
- Price
- $910
- Updated
- 2021/12/16
2-Amino-5-methylbenzoic acid Chemical Properties,Usage,Production
Chemical Properties
Light-Brown Solid
Uses
2-Amino-5-methylbenzoic acid can be used to synthesize quinazolinedione.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
3113-72-2
2941-78-8
General procedure for the synthesis of 2-amino-5-methylbenzoic acid from 5-methyl-2-nitrobenzoic acid: 5-methyl-2-nitrobenzoic acid (20 g, 110 mmol) was dissolved in ethanol and 10% palladium/carbon catalyst (1 g) was added. The reaction mixture was stirred overnight at room temperature and under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through diatomaceous earth and the filtrate was concentrated under reduced pressure to give 16 g (96% yield) of the white solid product 2-amino-5-methylbenzoic acid. Melting point: 162 °C. 1H NMR (DMSO-d6) δ: 2.13 (s, 3H), 6.65 (d, J=8.6 Hz, 1H), 7.06 (dd, J=8.6,1.8 Hz, 1H), 7.48 (d, J=1.1 Hz, 1H).EIMS m/z: 174 (M+1), 152 (M+23).
References
[1] Patent: WO2004/74218, 2004, A2. Location in patent: Page 97
[2] Patent: US2008/139551, 2008, A1. Location in patent: Page/Page column 41
[3] Journal of Organic Chemistry, 2016, vol. 81, # 19, p. 9046 - 9074
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982, # 8, p. 1637 - 1648
[5] Chemische Berichte, 1905, vol. 38, p. 3555
2-Amino-5-methylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-5-methylbenzoic acid Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 2-Amino-5-methylbenzoic acid manufacturers
- Product
- 2-Amino-5-methylbenzoic acid 2941-78-8
- Price
- US $40.00/Kg/Drum
- Min. Order
- 25Kg/Drum
- Purity
- 98.00%HPLC
- Supply Ability
- 10tons
- Release date
- 2021-11-09
- Product
- Fluralaner-032 2941-78-8
- Price
- US $0.00-0.00/mg
- Min. Order
- 5mg
- Purity
- 95%+
- Supply Ability
- 1000mg
- Release date
- 2025-02-10
- Product
- 2-Amino-5-methylbenzoic acid 2941-78-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27