ChemicalBook > CAS DataBase List > EXENDIN-4 (3-39)

EXENDIN-4 (3-39)

Product Name: EXENDIN-4 (3-39)
CAS No.: 196109-31-6
Chemical Name: EXENDIN-4 (3-39)
Synonyms: EXENDIN (3-39);EXENDIN-4 (3-39);M.W. 3992.42 C176H272N46O58S;EGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2;EGTFTSDLSK QMEEEAVRLF IEWLKNGGPS SGAPPPS -CONH2;GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;H-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
CBNumber: CB0777447
Molecular Formula: C176H272N46O58S
Formula Weight: 3992.38128
MOL File: 196109-31-6.mol

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EXENDIN-4 (3-39) Property

storage temp.: -15°C
Sequence: H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
InChIKey: ZCYIPGKMSDDSFW-TYVQEZQOSA-N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb364618
Product name: Exendin 4 (3-39)
Purity: > 95%
Packaging: 1mg
Price: $727.6
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364618
Product name: Exendin 4 (3-39)
Purity: > 95%
Packaging: 5mg
Price: $1802
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364618
Product name: Exendin 4 (3-39)
Purity: > 95%
Packaging: 10mg
Price: $2696.2
Updated: 2021/12/16

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EXENDIN-4 (3-39) Chemical Properties,Usage,Production

Uses

Exendin-4 (3-39) is a peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1 receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis[1][2].

in vivo

GLP-1 (i.p.; 5 μg/kg) increases circulating corticosterone and aldosterone levels^[2].

Animal Model:	Rats^[2]
Dosage:	5 μg/kg
Administration:	Intraperitoneal injections
Result:	Increased circulating corticosterone levels in a time-dependent manner both in conscious and anaesthetized rats and also increased aldosterone levels.

References

[1] David Parkes, et al. Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1. (2001), 53(4), 260–267.
[2] Affiliations, et al. GLP-1(7-36)-amide and Exendin-4 stimulate the HPA axis in rodents and humans. Endocrinology. 2010 Jun;151(6):2629-40. DOI:10.1210/en.2009-0915

EXENDIN-4 (3-39) Preparation Products And Raw materials

Raw materials

Preparation Products

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196109-31-6, EXENDIN-4 (3-39)Related Search:

SDV-Exendin-3/4 Exendin-3 (9-39) amide TERT-BUTYL ISOCYANIDE PHENYLSELENOL METHYL ISOCYANOACETATE SALCOMINE Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ferric acetylacetonate Ethyl isocyanoacetate Tris(2,4-pentanedionato)chroMiuM(III) 2,4-PENTANEDIONE, SILVER DERIVATIVE COBALT(II) ACETYLACETONATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Exendin-4 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Aluminum acetylacetonate

M.W. 3992.42 C176H272N46O58S

GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2

EGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

EXENDIN-4 (3-39)

EXENDIN (3-39)

H-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2

EGTFTSDLSK QMEEEAVRLF IEWLKNGGPS SGAPPPS -CONH2

196109-31-6

Glucagon receptor and related

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