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EXENDIN-4 (3-39)

Product Name
EXENDIN-4 (3-39)
CAS No.
196109-31-6
Chemical Name
EXENDIN-4 (3-39)
Synonyms
EXENDIN (3-39);EXENDIN-4 (3-39);M.W. 3992.42 C176H272N46O58S;EGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2;EGTFTSDLSK QMEEEAVRLF IEWLKNGGPS SGAPPPS -CONH2;GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;H-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
CBNumber
CB0777447
Molecular Formula
C176H272N46O58S
Formula Weight
3992.38128
MOL File
196109-31-6.mol
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EXENDIN-4 (3-39) Property

storage temp. 
-15°C
Sequence
H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
InChIKey
ZCYIPGKMSDDSFW-TYVQEZQOSA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb364618
Product name
Exendin 4 (3-39)
Purity
> 95%
Packaging
1mg
Price
$727.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364618
Product name
Exendin 4 (3-39)
Purity
> 95%
Packaging
5mg
Price
$1802
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364618
Product name
Exendin 4 (3-39)
Purity
> 95%
Packaging
10mg
Price
$2696.2
Updated
2021/12/16
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EXENDIN-4 (3-39) Chemical Properties,Usage,Production

Uses

Exendin-4 (3-39) is a peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1 receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis[1][2].

in vivo

GLP-1 (i.p.; 5 μg/kg) increases circulating corticosterone and aldosterone levels[2].

Animal Model:Rats[2]
Dosage:5 μg/kg
Administration:Intraperitoneal injections
Result:Increased circulating corticosterone levels in a time-dependent manner both in conscious and anaesthetized rats and also increased aldosterone levels.

References

[1] David Parkes, et al. Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1. (2001), 53(4), 260–267.
[2] Affiliations, et al. GLP-1(7-36)-amide and Exendin-4 stimulate the HPA axis in rodents and humans. Endocrinology. 2010 Jun;151(6):2629-40. DOI:10.1210/en.2009-0915

EXENDIN-4 (3-39) Preparation Products And Raw materials

Raw materials

Preparation Products

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EXENDIN-4 (3-39) Suppliers

PolyPeptide Laboratories GmbH
Tel
--
Fax
--
Email
info@polypeptide.de
Country
Germany
ProdList
408
Advantage
66

196109-31-6, EXENDIN-4 (3-39)Related Search:


  • M.W. 3992.42 C176H272N46O58S
  • GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • EGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
  • EXENDIN-4 (3-39)
  • EXENDIN (3-39)
  • H-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • EGTFTSDLSK QMEEEAVRLF IEWLKNGGPS SGAPPPS -CONH2
  • 196109-31-6
  • Glucagon receptor and related
  • peptide