3,5-Dichloro-2,4,6-trifluoropyridine
- Product Name
- 3,5-Dichloro-2,4,6-trifluoropyridine
- CAS No.
- 1737-93-5
- Chemical Name
- 3,5-Dichloro-2,4,6-trifluoropyridine
- Synonyms
- LABOTEST-BB LT00848192;,5-Dichlorotrifluoropyridine;3,5-DICHLOROTRIFLUOROPYRIDINE;2,6-DICHLORO-1,3,5-TRIFLUOROBENZENE;3,5-Dichloro2,4,6-trifloro pyridine;2,4,6-TRIFLUORO-3,5-DICHLOROPYRIDINE;3,5-DICHLORO-2,4,6-TRIFLUOROPYRIDINE;3,5-Dichlloro-2,4,6-trifluoropyridine;Pyridine, 3,5-dichloro-2,4,6-trifluoro-;3,5-Dichloro-2,4,6-trifluoropyridine>
- CBNumber
- CB1141939
- Molecular Formula
- C5Cl2F3N
- Formula Weight
- 201.96
- MOL File
- 1737-93-5.mol
3,5-Dichloro-2,4,6-trifluoropyridine Property
- Melting point:
- 23-24 °C
- Boiling point:
- 159-160 °C(lit.)
- Density
- 1.622 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.478(lit.)
- Flash point:
- >230 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -4.30±0.10(Predicted)
- Specific Gravity
- 1.622
- BRN
- 475874
- InChI
- InChI=1S/C5Cl2F3N/c6-1-3(8)2(7)5(10)11-4(1)9
- InChIKey
- PKSORSNCSXBXOT-UHFFFAOYSA-N
- SMILES
- C1(F)=NC(F)=C(Cl)C(F)=C1Cl
- CAS DataBase Reference
- 1737-93-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Pyridine, 3,5-dichloro-2,4,6-trifluoro-(1737-93-5)
- EPA Substance Registry System
- Pyridine, 3,5-dichloro-2,4,6-trifluoro- (1737-93-5)
Safety
- Hazard Codes
- Xi,T,T+
- Risk Statements
- 36/37/38-26
- Safety Statements
- 26-37/39-36-45-36/37-28
- RIDADR
- UN 3382 6.1/PG 1
- WGK Germany
- 3
- Hazard Note
- Toxic
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P284Wear respiratory protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P320Specific treatment is urgent (see … on this label).
P330Rinse mouth.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 3H32-6-35
- Product name
- 3,5-Dichlorotrifluoropyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $325
- Updated
- 2021/12/16
- Product number
- 3H32-6-35
- Product name
- 3,5-Dichlorotrifluoropyridine
- Purity
- 98%
- Packaging
- 100g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 004982
- Product name
- 3,5-Dichloro-2,4,6-trifluoropyridine
- Purity
- 98%
- Packaging
- 100g
- Price
- $117
- Updated
- 2021/12/16
- Product number
- HCH0020916
- Product name
- 3,5-DICHLORO-2,4,6-TRIFLUOROPYRIDINE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1073
- Updated
- 2021/12/16
- Product number
- HCH0020916
- Product name
- 3,5-DICHLORO-2,4,6-TRIFLUOROPYRIDINE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $2410.49
- Updated
- 2021/12/16
3,5-Dichloro-2,4,6-trifluoropyridine Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to pale yellow liquid
General Description
A colorless liquid. Insoluble in water and denser than water. Hence sinks in water. Contact may irritate skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
3,5-DICHLORO-2,4,6-TRI-FLUOROPYRIDINE is a halogenated amine. Behaves as a weak chemical base, neutralizing acids in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.
Synthesis
2176-62-7
1737-93-5
The general procedure for the synthesis of 3,5-dichloro-2,4,6-trifluoropyridine from pentachloropyridine (2,3,4,5,6-pentachloropyridine) was as follows: in a 1000mL three-necked flask, 600mL of DMI (1,3-dimethyl-2-imidazolidinone) and 146.72g of anhydrous KF (potassium fluoride) (purity of 99%, particle size of 20-50 μm) were added. 60 g of solvent was removed by stirring distillation under reduced pressure (130-135 °C/60 mmHg), and the system was heated to 90 °C after the moisture content was determined to be less than 1000 ppm by water evaporation. Subsequently, 129.40 g of pentachloropyridine of 97% purity was added, the reaction temperature was maintained at 90 °C and stirred for 1.5 hours. Upon completion of the reaction, the heating was stopped and the reaction mixture was cooled to room temperature. The reaction mixture was filtered and the filtrate and solid residue were obtained by separation. The solid residue was washed with 100 mL of DMI and diafiltrated to obtain the wash solution. The wash solution and initial filtrate were combined and a distillation operation was carried out to collect the fractions at a pressure of 65-70.5 KPa to obtain the target product 3,5-dichloro-2,4,6-trifluoropyridine.
References
[1] Patent: CN106008331, 2016, A. Location in patent: Paragraph 0059; 0063
[2] Patent: CN108017574, 2018, A. Location in patent: Paragraph 0040-0043; 0052
[3] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 24, p. 3623 - 3627
[4] Russian Chemical Bulletin, 2007, vol. 56, # 11, p. 2239 - 2246
[5] Patent: CN106187872, 2016, A. Location in patent: Paragraph 0027; 0028; 0029
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View Lastest Price from 3,5-Dichloro-2,4,6-trifluoropyridine manufacturers
- Product
- 3,5-Dichloro-2,4,6-trifluoropyridine 1737-93-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-02
- Product
- 3,5-Dichloro-2,4,6-trifluoropyridine 1737-93-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 3,5-Dichloro-2,4,6-trifluoropyridine 1737-93-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11