ChemicalBook > CAS DataBase List > 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

Product Name
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
CAS No.
82373-94-2
Chemical Name
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
Synonyms
THSG;Astragalus polyphenols;Tetrahydroxystilbene glucoside;2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP;(2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;EH-201;EH-201/THSG;CHEMBL460860;He Shou wu extract;stilbene glycoside
CBNumber
CB11481832
Molecular Formula
C20H22O9
Formula Weight
406.39
MOL File
82373-94-2.mol
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2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Property

Boiling point:
715.0±60.0 °C(Predicted)
Density 
1.593±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: soluble5mg/mL, clear (warmed)
form 
powder
pka
8.78±0.40(Predicted)
color 
white to brown
InChI
InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/s3
InChIKey
JAYVHSBYKLLDJC-BGLDUWRXNA-N
SMILES
O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1C(=CC(O)=CC=1/C=C/C1C=CC(O)=CC=1)O |&1:1,2,3,5,7,r|
CAS DataBase Reference
82373-94-2
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26
WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0834
Product name
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity
≥98% (HPLC)
Packaging
5mg
Price
$103
Updated
2024/03/01
Sigma-Aldrich
Product number
1651654
Product name
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$326
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL82666
Product name
2,3,4′,5-Tetrahydroxystilbene 2-glucoside
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$425
Updated
2023/06/20
Sigma-Aldrich
Product number
SML0834
Product name
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity
≥98% (HPLC)
Packaging
25mg
Price
$334
Updated
2024/03/01
AK Scientific
Product number
Y0006
Product name
2,3,5,4-tetrahydroxyldiphenylethylene-2-O-beta-D-glucoside
Packaging
50mg
Price
$190
Updated
2021/12/16
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2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Chemical Properties,Usage,Production

Description

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside is derived from the root of Polygonaceae species Polygonum multiflorum and is a stilbene compound. It has antioxidant, hypotensive, anti-aging, anti-inflammatory, hypolipidemic, cardioprotective and neuroprotective effects. It can also inhibit the formation of 5-HETE, HHT and thromboxane B2.

Uses

2,3,4'',5-Tetrahydroxystilbene 2-O-Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB/OC-2 cells from H2O2-induced autophagy and apoptosis in vitro.

Definition

ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols.

General Description

2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol.

Biochem/physiol Actions

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.

Physiological effects

Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis.

2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside manufacturers

Hovane Phytochemicals Co., Ltd
Product
2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside 82373-94-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
90%HPLC
Supply Ability
1 ton
Release date
2024-11-07
Changsha Staherb Natural Ingredients Co., Ltd.
Product
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
Price
US $0.00/MG
Min. Order
10MG
Purity
>98% HPLC
Supply Ability
1000KG
Release date
2022-09-19
Shanghai Standard Technology Co., Ltd.
Product
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-19

82373-94-2, 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucosideRelated Search:


  • 2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside
  • EH-201
  • Tetrahydroxystilbene glucoside
  • THSG
  • CHEMBL460860
  • Astragalus polyphenols
  • 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid
  • 2,3,4,5-Tetrahydroxystilbene 2-glucoside
  • 82373-94-2 2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside
  • 2,3,5,4-Tetrahydroxyl-diphenyl
  • 2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside 82373-94-2
  • (2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
  • 2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside
  • 2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucosi
  • 2,3,5,4' -tetrahydroxystibene -2-O-β-D –glucoside
  • 2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside
  • 4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
  • 2,3,4',5-Tetrahydroxystilbene 2-O-Glucoside
  • 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 98%, from Fallopia multiflora (Thunb.) Harald.
  • 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside)
  • 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside
  • β-D-Glucopyranoside, 2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
  • 2,3,5,4'-Tetrahydroxy stilbene 2-Ο-β-D-glucoside
  • b-D-Glucopyranoside,2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
  • 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid
  • (2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
  • 2,3,5,4'-tetrahydroxystilbene-2
  • 2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-Glucopyranoside
  • 2,4-Dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenyl beta-D-Glucopyranoside
  • 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP
  • EH-201/THSG
  • (2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • (2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)...
  • 2,3,5,4' -tetrahydroxystibene -2-O-β-D –glucoside
  • TIANFUCHEM--82373-94-2--2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
  • He Shou wu extract
  • stilbene glycoside
  • -Tetrahydroxy stilbene-2-Ο-β-D-glucoside
  • 2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside
  • 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
  • 2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside
  • 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside
  • 2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside
  • 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside|||2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside|||2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside|||Astragalus polyphenols
  • 2,3,5,4’-Tetrahydroxystilbene 2-O-β-D-glucoside
  • 2,3,5,4'-Tetrahydroxyl-diphenylethylene-2-O-beta-D-glucoside
  • 2,3,4`,5-Tetrahydroxystilbene 2-glucoside-RM
  • 2,3,5,4'-Tetrahydroxystilbene 2-O-glucosidet
  • 2,3,5,4′-Tetrahydroxystilbene
  • 82373-94-2
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors