2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
- Product Name
- 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
- CAS No.
- 82373-94-2
- Chemical Name
- 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
- Synonyms
- THSG;Astragalus polyphenols;Tetrahydroxystilbene glucoside;2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP;(2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;EH-201;EH-201/THSG;CHEMBL460860;He Shou wu extract;stilbene glycoside
- CBNumber
- CB11481832
- Molecular Formula
- C20H22O9
- Formula Weight
- 406.39
- MOL File
- 82373-94-2.mol
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Property
- Boiling point:
- 715.0±60.0 °C(Predicted)
- Density
- 1.593±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble5mg/mL, clear (warmed)
- form
- powder
- pka
- 8.78±0.40(Predicted)
- color
- white to brown
- InChI
- InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/s3
- InChIKey
- JAYVHSBYKLLDJC-BGLDUWRXNA-N
- SMILES
- O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1C(=CC(O)=CC=1/C=C/C1C=CC(O)=CC=1)O |&1:1,2,3,5,7,r|
- CAS DataBase Reference
- 82373-94-2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0834
- Product name
- 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $103
- Updated
- 2024/03/01
- Product number
- 1651654
- Product name
- 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50mg
- Price
- $326
- Updated
- 2024/03/01
- Product number
- PHL82666
- Product name
- 2,3,4′,5-Tetrahydroxystilbene 2-glucoside
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $425
- Updated
- 2023/06/20
- Product number
- SML0834
- Product name
- 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $334
- Updated
- 2024/03/01
- Product number
- Y0006
- Product name
- 2,3,5,4-tetrahydroxyldiphenylethylene-2-O-beta-D-glucoside
- Packaging
- 50mg
- Price
- $190
- Updated
- 2021/12/16
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Chemical Properties,Usage,Production
Uses
2,3,4'',5-Tetrahydroxystilbene 2-O-Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB/OC-2 cells from H2O2-induced autophagy and apoptosis in vitro.
Definition
ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols.
General Description
2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol.
Biochem/physiol Actions
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.
Physiological effects
Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis.
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Suppliers
- Tel
- --
- Fax
- --
- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
View Lastest Price from 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside manufacturers
- Product
- 2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside 82373-94-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 90%HPLC
- Supply Ability
- 1 ton
- Release date
- 2024-11-07
- Product
- 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
- Price
- US $0.00/MG
- Min. Order
- 10MG
- Purity
- >98% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-19
- Product
- 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-19