2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

Product Name: 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
CAS No.: 82373-94-2
Chemical Name: 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
Synonyms: THSG;Astragalus polyphenols;Tetrahydroxystilbene glucoside;2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP;(2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;EH-201;EH-201/THSG;CHEMBL460860;He Shou wu extract;stilbene glycoside
CBNumber: CB11481832
Molecular Formula: C20H22O9
Formula Weight: 406.39
MOL File: 82373-94-2.mol

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2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Property

Boiling point:: 715.0±60.0 °C(Predicted)
Density: 1.593±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H2O: soluble5mg/mL, clear (warmed)
form: powder
pka: 8.78±0.40(Predicted)
color: white to brown
InChI: InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/s3
InChIKey: JAYVHSBYKLLDJC-BGLDUWRXNA-N
SMILES: O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1C(=CC(O)=CC=1/C=C/C1C=CC(O)=CC=1)O |&1:1,2,3,5,7,r|
CAS DataBase Reference: 82373-94-2

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26
WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0834
Product name: 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $103
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1651654
Product name: 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $326
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL82666
Product name: 2,3,4′,5-Tetrahydroxystilbene 2-glucoside
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $425
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML0834
Product name: 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $334
Updated: 2024/03/01

AK Scientific

Product number: Y0006
Product name: 2,3,5,4-tetrahydroxyldiphenylethylene-2-O-beta-D-glucoside
Packaging: 50mg
Price: $190
Updated: 2021/12/16

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2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Chemical Properties,Usage,Production

Description

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside is derived from the root of Polygonaceae species Polygonum multiflorum and is a stilbene compound. It has antioxidant, hypotensive, anti-aging, anti-inflammatory, hypolipidemic, cardioprotective and neuroprotective effects. It can also inhibit the formation of 5-HETE, HHT and thromboxane B2.

Uses

2,3,4'',5-Tetrahydroxystilbene 2-O-Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB/OC-2 cells from H2O2-induced autophagy and apoptosis in vitro.

Definition

ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols.

General Description

2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol.

Biochem/physiol Actions

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.

Physiological effects

Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis.

2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Suppliers

China 220 India 1 Japan 1 United States 14 Global 236

Guilin Benefittw Biotechnology Co.,LTD.

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Sichuan Hongen Plant Technology Co., Ltd.

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Shenzhen Sungening Bio-Tech Co., Ltd

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Dalian Meilun Biotech Co., Ltd.

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View Lastest Price from 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside manufacturers

Hovane Phytochemicals Co., Ltd

Product: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside 82373-94-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 90%HPLC
Supply Ability: 1 ton
Release date: 2024-11-07

Changsha Staherb Natural Ingredients Co., Ltd.

Product: 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
Price: US $0.00/MG
Min. Order: 10MG
Purity: >98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-19

Shanghai Standard Technology Co., Ltd.

Product: 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 82373-94-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-19

82373-94-2, 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucosideRelated Search:

Baicalin Benzil ISOQUERCITRIN Asiaticoside AURANTIO-OBTUSIN Arbutin Madecassic acid Hydroxytyrosol Madecassoside Asiatic acid Centella asiatica extract Madecassic acid PINOSYLVIN 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside 4-Hexyloxyphenol Resveratrol 4-(6-Hydroxyhexyloxy)phenol 2-STYRYLBENZENOL

2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside

EH-201

Tetrahydroxystilbene glucoside

THSG

CHEMBL460860

Astragalus polyphenols

2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid

2,3,4,5-Tetrahydroxystilbene 2-glucoside

82373-94-2 2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside

2,3,5,4-Tetrahydroxyl-diphenyl

2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside 82373-94-2

(2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol

2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside

2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucosi

2,3,5,4' -tetrahydroxystibene -2-O-β-D –glucoside

2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside

4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

2,3,4',5-Tetrahydroxystilbene 2-O-Glucoside

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 98%, from Fallopia multiflora (Thunb.) Harald.

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside)

2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside

β-D-Glucopyranoside, 2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl

2,3,5,4'-Tetrahydroxy stilbene 2-Ο-β-D-glucoside

b-D-Glucopyranoside,2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl

2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid

(2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside

2,3,5,4'-tetrahydroxystilbene-2

2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-Glucopyranoside

2,4-Dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenyl beta-D-Glucopyranoside

2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP

EH-201/THSG

(2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

(2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)...

2,3,5,4' -tetrahydroxystibene -2-O-β-D –glucoside

TIANFUCHEM--82373-94-2--2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

He Shou wu extract

stilbene glycoside

-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside

2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside

2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside

2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside|||2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside|||2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside|||Astragalus polyphenols

2,3,5,4’-Tetrahydroxystilbene 2-O-β-D-glucoside

2,3,5,4'-Tetrahydroxyl-diphenylethylene-2-O-beta-D-glucoside

2,3,4`,5-Tetrahydroxystilbene 2-glucoside-RM

2,3,5,4'-Tetrahydroxystilbene 2-O-glucosidet

2,3,5,4′-Tetrahydroxystilbene

82373-94-2

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Inhibitors