AG 825

Product Name: AG 825
CAS No.: 149092-50-2
Chemical Name: AG 825
Synonyms: AG 825;Zinc02572484;TYRPHOSTIN C15;AG 825 USP/EP/BP;TYRPHOSTIN AG 825;AG 825, ErbB2 inhibitor;AG 825 (Tyrphostin AG 825);AG 825 - CAS 149092-50-2 - Calbiochem;4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE;5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
CBNumber: CB1283828
Molecular Formula: C19H15N3O3S2
Formula Weight: 397.47
MOL File: 149092-50-2.mol

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AG 825 Property

storage temp.: −20°C
solubility: DMSO: soluble
form: Yellow solid
color: Light yellow to yellow
Sensitive: Light Sensitive

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T5443
Product name: Tyrphostin AG 825
Purity: ≥92.5%
Packaging: 2mg
Price: $52.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 121765
Product name: AG 825
Packaging: 2mg
Price: $172
Updated: 2024/03/01

Alfa Aesar

Product number: J65227
Product name: Tyrphostin C15
Packaging: 10mg
Price: $233.65
Updated: 2024/03/01

Cayman Chemical

Product number: 10010243
Product name: AG 825
Purity: ≥98%
Packaging: 1mg
Price: $28
Updated: 2024/03/01

Cayman Chemical

Product number: 10010243
Product name: AG 825
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

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AG 825 Chemical Properties,Usage,Production

Uses

A selective ErbB2 inhibitor

Uses

AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.

Definition

ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

Biological Activity

Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

storage

Store at +4°C

AG 825 Preparation Products And Raw materials

Raw materials

Preparation Products

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AG 825 Suppliers

China 60 Germany 4 India 1 Switzerland 2 United Kingdom 5 United States 23 USA 1 Global 96

VDM Biochemicals

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EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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BIOMOL INTERNATIONAL, LP

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149092-50-2, AG 825Related Search:

AG 1478 HYDROCHLORIDE DAPH AG 18 LAVENDUSTIN A METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH TYRPHOSTIN A25 Canertinib 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol AG 213 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE PD168393 TYRPHOSTIN A51 CIVENTICHEM CV-409 AG 825 AG 99 4-METHYL-2-[(METHYLTHIO)METHYL]PHENOL AKOS BBS-00008114

TYRPHOSTIN AG 825

TYRPHOSTIN C15

AG 825

5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE

5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE

4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE

3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- 2-Propenamide

Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide

AG 825 (Tyrphostin AG 825)

(E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE

AG 825 - CAS 149092-50-2 - Calbiochem

Zinc02572484

2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-

AG 825 USP/EP/BP

3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide

AG 825, ErbB2 inhibitor

149092-50-2

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Kinase/Phosphatase Biology

Receptor Tyrosine Kinase Inhibitors

Epidermal Growth Factor Receptor (EGFR)

Protein Kinase