ChemicalBook > CAS DataBase List > Propargyl-PEG8-t-butyl ester

Propargyl-PEG8-t-butyl ester

Product Name
Propargyl-PEG8-t-butyl ester
CAS No.
2055014-96-3
Chemical Name
Propargyl-PEG8-t-butyl ester
Synonyms
CAS_2055014-96-3;Propargyl-PEG8-Boc;Propargyl-PEG8-COOtBu;Propargyl-PEG7-C2-COOtBu;Propargyl-PEG8-t-Bu Ester;Propargyl-PEG7-CH2CH2COOtBu;Propargyl-PEG8-t-butyl ester;Propargyl-PEG8-tert-butyl Ester;4,7,10,13,16,19,22,25-octaoxaco-27-tert-butyl alkynate;4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 1,1-dimethylethyl ester
CBNumber
CB13134215
Molecular Formula
C24H44O10
Formula Weight
492.6
MOL File
2055014-96-3.mol
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Propargyl-PEG8-t-butyl ester Property

Boiling point:
528.4±45.0 °C(Predicted)
Density 
1.064±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H401Toxic to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS107867
Product name
Propargyl-PEG7-CH2CH2COOtBu
Purity
97%
Packaging
250mg
Price
$346
Updated
2021/12/16
BroadPharm
Product number
BP-22810
Product name
Propargyl-PEG8-t-butylester
Purity
98%
Packaging
250mg
Price
$390
Updated
2021/12/16
Apolloscientific
Product number
BIPG1749
Product name
Propargyl-PEG8-t-butyl ester
Packaging
100mg
Price
$428
Updated
2021/12/16
BroadPharm
Product number
BP-22810
Product name
Propargyl-PEG8-t-butylester
Purity
98%
Packaging
500mg
Price
$580
Updated
2021/12/16
Acrotein
Product number
B-1480
Product name
Propargyl-PEG7-CH2CH2COOtBu
Purity
97%
Packaging
0.25g
Price
$220
Updated
2021/12/16
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Propargyl-PEG8-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG8-t-butyl ester is a PEG reagent with an alkyne group and a t-butyl group. The alkyne group enables the formation of triazole linkage with azide-bearing compounds or biomolecules; copper is required as a catalyst. The t-butyl group can be hydrolyzed under acidic conditions. The hydrophicility of the molecule is improved by having 8 units of PEG.

Uses

Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.

Propargyl-PEG8-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG8-t-butyl ester Suppliers

China 42 United Kingdom 1 United States 3 Global 46
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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View Lastest Price from Propargyl-PEG8-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG8-COOtBu 2055014-96-3
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

2055014-96-3, Propargyl-PEG8-t-butyl esterRelated Search:

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  • Propargyl-PEG8-t-butyl ester
  • Propargyl-PEG8-COOtBu
  • CAS_2055014-96-3
  • Propargyl-PEG7-CH2CH2COOtBu
  • Propargyl-PEG8-Boc
  • 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 1,1-dimethylethyl ester
  • Propargyl-PEG8-t-Bu Ester
  • Propargyl-PEG7-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 1,1-dimethylethyl ester
  • Propargyl-PEG7-C2-COOtBu
  • 4,7,10,13,16,19,22,25-octaoxaco-27-tert-butyl alkynate
  • Propargyl-PEG8-tert-butyl Ester
  • 2055014-96-3
  • C24H44O10
  • peg