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Azido-PEG1-methyl ester

Product Name
Azido-PEG1-methyl ester
CAS No.
1835759-80-2
Chemical Name
Azido-PEG1-methyl ester
Synonyms
Azido-PEG1-methyl ester
CBNumber
CB13162861
Molecular Formula
C6H11N3O3
Formula Weight
173.17
MOL File
1835759-80-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22934
Product name
Azido-PEG1-methylester
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22934
Product name
Azido-PEG1-methylester
Purity
98%
Packaging
250mg
Price
$450
Updated
2021/12/16
BroadPharm
Product number
BP-22934
Product name
Azido-PEG1-methylester
Purity
98%
Packaging
500mg
Price
$660
Updated
2021/12/16
BroadPharm
Product number
BP-22934
Product name
Azido-PEG1-methylester
Purity
98%
Packaging
1g
Price
$980
Updated
2021/12/16
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Azido-PEG1-methyl ester Chemical Properties,Usage,Production

Description

Azido-PEG1-methyl ester is a crosslinker containing an azide group and a methyl ester. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Azido-PEG1-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG1-methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG1-methyl ester Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58