Boc-Aminooxy-PEG3-amine
- Product Name
- Boc-Aminooxy-PEG3-amine
- CAS No.
- 1235514-18-7
- Chemical Name
- Boc-Aminooxy-PEG3-amine
- Synonyms
- CAS_1235514-18-7;BocHNO-PEG3-CH2CH2NH2;Boc-HNO-PEG3-CH2CH2NH3;Boc-Aminooxy-PEG3-amine;Boc-Aminooxy-PEG3-C2-NH2;t-Boc-Aminoxy-PEG3-amine;t-Boc-Aminooxy-PEG3-amine;2-[2-[2-[2-[(Boc-amino)oxy]ethoxy]ethoxy]ethoxy]ethanamine;tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxycarbamate;3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-amino-, 1,1-dimethylethyl ester
- CBNumber
- CB13162902
- Molecular Formula
- C13H28N2O6
- Formula Weight
- 308.37
- MOL File
- 1235514-18-7.mol
Boc-Aminooxy-PEG3-amine Property
- Density
- 1.083±0.06 g/cm3(Predicted)
- pka
- 8.74±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-23127
- Product name
- t-Boc-Aminooxy-PEG3-amine
- Purity
- 98%
- Packaging
- 100mg
- Price
- $330
- Updated
- 2021/12/16
Boc-Aminooxy-PEG3-amine Chemical Properties,Usage,Production
Description
t-Boc-Aminooxy-PEG3-amine is a Boc-protected aminooxy molecule. The amine (NH2) group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc-aminooxy can be deprotected under mild acidic conditions and then reacts with an aldehyde to form a linkage.
Uses
Boc-Aminooxy-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-Aminooxy-PEG3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Boc-Aminooxy-PEG3-amine manufacturers
- Product
- t-Boc-Aminooxy-PEG3-amine 1235514-18-7
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22