Adenine
- Product Name
- Adenine
- CAS No.
- 73-24-5
- Chemical Name
- Adenine
- Synonyms
- 9H-Purin-6-amine;Adenin;6-AMINOPURINE;Vitamin B4;7H-PURIN-6-AMINE;Ade;ANE;Purin-6-amine;1H-PURIN-6-AMINE;6-Amino-9H-purine
- CBNumber
- CB1323708
- Molecular Formula
- C5H5N5
- Formula Weight
- 135.13
- MOL File
- 73-24-5.mol
Adenine Property
- Melting point:
- >360 °C (lit.)
- Boiling point:
- 238.81°C (rough estimate)
- Density
- 1.3795 (rough estimate)
- refractive index
- 1.7000 (estimate)
- Flash point:
- 220°C
- storage temp.
- 2-8°C
- solubility
- 0.5 M HCl: soluble20mg/mL, Grade III, colorless to faint yellow or tan
- pka
- 4.12(at 25℃)
- form
- Liquid or Solid
- color
- Clear colorless to light yellow
- Odor
- Odorless
- PH Range
- 7
- Water Solubility
- 0.5 g/L (20 ºC)
- Sublimation
- 220 ºC
- Merck
- 14,152
- BRN
- 5777
- Stability:
- Stable. Moisture-sensitive. Incompatible with strong oxidizing agents.
- InChIKey
- GFFGJBXGBJISGV-UHFFFAOYSA-N
- LogP
- -0.090
- CAS DataBase Reference
- 73-24-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Adenine(73-24-5)
- EPA Substance Registry System
- Adenine (73-24-5)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-20/21/22
- Safety Statements
- 26-36
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- AU6125000
- F
- 8-10-23
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29335990
- Toxicity
- LD50 orally in rats: 745 mg/kg (Philips)
N-Bromosuccinimide Price
- Product number
- 1152-M
- Product name
- Adenine - CAS 73-24-5 - Calbiochem
- Purity
- Synthetic, therefore free of any contamination with related natural products.
- Packaging
- 10g
- Price
- $97.6
- Updated
- 2024/03/01
- Product number
- 1152-M
- Product name
- Adenine - CAS 73-24-5 - Calbiochem
- Purity
- Synthetic, therefore free of any contamination with related natural products.
- Packaging
- 25g
- Price
- $114
- Updated
- 2024/03/01
- Product number
- 1152-M
- Product name
- Adenine - CAS 73-24-5 - Calbiochem
- Purity
- Synthetic, therefore free of any contamination with related natural products.
- Packaging
- 100g
- Price
- $389
- Updated
- 2024/03/01
- Product number
- 1012101
- Product name
- Adenine
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $394
- Updated
- 2024/03/01
- Product number
- A0149
- Product name
- Adenine
- Purity
- >99.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $72
- Updated
- 2024/03/01
Adenine Chemical Properties,Usage,Production
Description
adenine is one of the purine nitrogenous bases that composes DNA and RNA; composed of two carbon–nitrogen rings. Adenine bonds with thymine in DNA and with uracil in RNA (see base pairing rule); it is also a major component of other molecules such as adenosine triphosphate.
Chemical Properties
Adenine is a prominent member of the family of naturally occurring purines. Adenine occurs not only in ribonucleic acids (RNA), and deoxyribonucleic acids (DNA), but in nucleosides, such as adenosine, and nucleotides, such as adenylic acid, which may be linked with enzymatic functions quite apart from nucleic acids. Adenine, in the form of its ribonucleotide, is produced in mammals and fowls endogenously from smaller molecules and no nutritional essentiality is ascribed to it. In the nucleosides, nucleotides, and nucleic acids, the attachment or the sugar moiety is at position 9.
The purines and pyrimidines absorb ultraviolet light readily, with absorption peaks at characteristic frequencies. This has aided in their identification and quantitative determination.
Physical properties
Adenine is a white to almost white crystalline powder that is an important biological compound found in deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and adenosine triphosphate (ATP). It was once commonly referred to as vitamin B4 but is no longer considered a vitamin. Adenine is derived from purine. Purine is a heterocyclic compound.
History
Adenine is one of the two purines found in DNA and RNA. The other is guanine. Adenine and guanine are called bases in reference to DNA and RNA. A nucleic acid base attached to ribose forms a ribonucleoside. Adenine combined with ribose produces the nucleoside adenosine.
Uses
Adenine is used as an active component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron. It is useful as a local antiseptic and vitamin B4. Further, it is used in the microbial determination of niacin. It is also employed as a food supplement for adult rats to investigate the effects of dietary adenine overload. In addition to this, it is used in the production of nucleotides of the nucleic acids.
Definition
ChEBI: Adenine is the parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. It has a role as a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purine nucleobase and a member of 6-aminopurines. It derives from a hydride of a 9H-purine.
Application
Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coa laninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.
Synthesis Reference(s)
Journal of the American Chemical Society, 88, p. 3829, 1966 DOI: 10.1021/ja00968a028
General Description
Adenine is a purine nucleobase. It is part of DNA, and RNA. Adenine is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP). It is a nitrogenous base found in DNA and RNA. It is also a constituent of certain coenzymes and when combined with the sugar ribose it forms the nucleoside adenosine found in AMP, ADP, and ATP. Adenine has a purine ring structure. It is one of the major component bases ofnucleotides and the nucleic acidsDNA and RNA.
Biochem/physiol Actions
Adenine is essential for many in vivo and in vitro biochemical processes. Adenine is converted to adenosine with ribose. On phosphorylation, it forms AMP, ADP and ATP. ATP is the energy currency of the cell and is required during cellular metabolism. Adenine is metabolized to is 2,8-dihydroxyadenine, which on accumulation in proximal tubules leads to the induction of chronic kidney disease (CKD) with severe anemia in rats. Adenine based derivatives elicit antiviral functionality against dsDNA viruses and are exploited for generating antiviral scaffolds.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
Purification Methods
Crystallise adenine from distilled water. [Beilstein 26 III/IV 3561.]
Adenine Preparation Products And Raw materials
Raw materials
Preparation Products
Adenine Suppliers
- Tel
- 0510-88770633 13961738808
- jingyaobiotech@126.com
- Country
- China
- ProdList
- 301
- Advantage
- 55
- Tel
- 021-021-56152668 18116302010
- Fax
- 18116300787
- sharing@sharingtechcn.com
- Country
- China
- ProdList
- 502
- Advantage
- 58
- Tel
- 19107255884
- 2013537414@qq.com
- Country
- China
- ProdList
- 501
- Advantage
- 58
- Tel
- +86-0371-55215939 +86-17319721973
- foreignsales@jiushichem.com
- Country
- China
- ProdList
- 33
- Advantage
- 58
- Tel
- 0373-6014999 18937330588
- xxycswsale@163.com
- Country
- China
- ProdList
- 55
- Advantage
- 58
- Tel
- 027-68897569 18120462897
- Fax
- 027-68897569
- fiona@yuanmengbio.com
- Country
- China
- ProdList
- 432
- Advantage
- 58
- Tel
- 021-59167510 18117107507
- vip@med-life.cn
- Country
- China
- ProdList
- 5019
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006608290; 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40241
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15848
- Advantage
- 69
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1998
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30132
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2341
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24539
- Advantage
- 81
- Tel
- 0757-86329057 18501085097
- Fax
- 010-89508210
- sales3.gd@hwrkchemical.com
- Country
- China
- ProdList
- 7583
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44751
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 18217
- Advantage
- 66
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12426
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9984
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9551
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11660
- Advantage
- 64
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 17939
- Advantage
- 64
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32344
- Advantage
- 50
- Tel
- 0712-0712-2580635 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8849
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3296
- Advantage
- 57
- Tel
- 13355009207 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18739
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12990
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11726
- Advantage
- 57
- Tel
- 400-188-0725 +86 21 34310725 13611771617
- Fax
- +86 21 34311076
- Country
- China
- ProdList
- 2002
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14443
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9823
- Advantage
- 79
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 4548
- Advantage
- 62
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4388
- Advantage
- 65
- Tel
- 0086-755-86198205
- acinfo@aemonchem.com
- Country
- China
- ProdList
- 1937
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11714
- Advantage
- 57
- Tel
- 86-28-85159085
- Fax
- 86-28-85152372
- info@aktinchem.com
- Country
- China
- ProdList
- 297
- Advantage
- 62
- Tel
- 021-33690831-8001 13552411790
- Fax
- 021-33690831
- postmaster@tyjchem.cn
- Country
- China
- ProdList
- 1542
- Advantage
- 55
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9664
- Advantage
- 60
- Tel
- 027-027-59207852 13308628970
- Fax
- QQ3130921841
- buy@fortunachem.com
- Country
- China
- ProdList
- 2893
- Advantage
- 58
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4647
- Advantage
- 58
- Tel
- 0871-65217109 13211707573;
- Fax
- 0871-65215563
- y.liu@mail.biobiopha.com
- Country
- China
- ProdList
- 5654
- Advantage
- 65
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4941
- Advantage
- 60
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9725
- Advantage
- 55
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 4979
- Advantage
- 50
- Tel
- 0755-83725681-603
- Fax
- +86 755 28094224
- Country
- China
- ProdList
- 4505
- Advantage
- 50
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9872
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17779
- Advantage
- 75
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12338
- Advantage
- 58
View Lastest Price from Adenine manufacturers
- Product
- Adenine 73-24-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200mt
- Release date
- 2021-12-02
- Product
- Adenine 73-24-5
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-03-22
- Product
- Adenosine Ep Impurity A 73-24-5
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 99.90%
- Supply Ability
- 10kg/month
- Release date
- 2023-05-10