Fleroxacin
- Product Name
- Fleroxacin
- CAS No.
- 79660-72-3
- Chemical Name
- Fleroxacin
- Synonyms
- AM-833;QUINODIS;MEGALONE;MEGALOCIN;RO-23-6240;FLEROXACIN;ro23-6240/000;Fleroxacin>Erlotinib-d12 HCl;Fleroxacin, >=99%
- CBNumber
- CB1331989
- Molecular Formula
- C17H18F3N3O3
- Formula Weight
- 369.34
- MOL File
- 79660-72-3.mol
Fleroxacin Property
- Melting point:
- 264-266°C
- Boiling point:
- 535.3±50.0 °C(Predicted)
- Density
- 1.409±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 0.1 M NaOH: soluble10mg/mL
- form
- solid
- pka
- -0.54±0.20(Predicted)
- color
- white to off-white
- Merck
- 14,4099
- CAS DataBase Reference
- 79660-72-3(CAS DataBase Reference)
Safety
- WGK Germany
- 2
- RTECS
- VB1999050
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H371May cause damage to organs
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F6807
- Product name
- Fleroxacin
- Purity
- ≥98% (HPLC)
- Packaging
- 1g
- Price
- $631
- Updated
- 2023/06/20
- Product number
- 33930
- Product name
- Fleroxacin
- Purity
- VETRANAL?, analytical standard
- Packaging
- 100MG
- Price
- $122
- Updated
- 2022/05/15
- Product number
- F0646
- Product name
- Fleroxacin
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $147
- Updated
- 2024/03/01
- Product number
- F0646
- Product name
- Fleroxacin
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $574
- Updated
- 2024/03/01
- Product number
- 24173
- Product name
- Fleroxacin
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $57
- Updated
- 2024/03/01
Fleroxacin Chemical Properties,Usage,Production
Description
Fleroxacin is a new, once daily trifluoroquinolone antibacterial structurally related to norfloxacin. Available in both oral and IV formulations, it is reportedly useful in the treatment of gonorrhea, bacterial enteritis, chronic bronchitis and urinary tract infections. Fleroxacin has a longer serum half-life (9-12 hours) than other drugs of this class, such as ciprofloxacin, enoxacin and norfloxacin.
Chemical Properties
White Needle-Like Crystals
Originator
Kyorin (Japan)
Uses
An antibacterial.
Uses
antibiotic
Definition
ChEBI: A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-n gative bacteria.
Manufacturing Process
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-
oxoquinoline-3-carboxylic acid hydrochloride:
A mixed solution of 1-methylpiperazine (0.34 g) and pyridine (3 ml) was
added to 6,7,8-trifluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxoquinoline-3-
carboxylic acid (0.12 g) and heated to reflux for 6 hours. After the solvent
evaporated and cooled, the residue was adjusted to pH 1 with aqueous
hydrochloric acid. The cooled mixture was filtered off and the solid
recrystallized from water to give 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-
(4-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (0.08
g), melting point 269-271°C (decomp.).
brand name
Quinodis
Therapeutic Function
Antibacterial
Fleroxacin Preparation Products And Raw materials
Raw materials
Preparation Products
Fleroxacin Suppliers
- Tel
- 800-8834567
- Fax
- 0396-3815761
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- Country
- China
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- 185-0276-2003 18502762003;
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- China
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- 010-82848833 400-666-7788
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- 86-10-82849933
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- China
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- 96815
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- 021-61259108 18621169109
- Fax
- 86-21-61259102
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- China
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- 40228
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- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
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- Country
- China
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- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
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- China
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- 021-67121386
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- China
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- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
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- Country
- China
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- 44688
- Advantage
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- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
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- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
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- 9809
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View Lastest Price from Fleroxacin manufacturers
- Product
- Fleroxacin 79660-72-3
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-18
- Product
- Fleroxacin 79660-72-3
- Price
- US $1.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2024-08-20
- Product
- Fleroxacin 79660-72-3
- Price
- US $36.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-16