ChemicalBook > CAS DataBase List > GLP-1 (7-37)

GLP-1 (7-37)

Product Name
GLP-1 (7-37)
CAS No.
106612-94-6
Chemical Name
GLP-1 (7-37)
Synonyms
Tglp-1;GLP-1, 7-37;HuMan GLP-1;Glp-I (7-37);insulinotropin;GLP-1(7-37), >98%;Human GLP-1 (7-37);GLP-1 acetate salt;GLP-1 (7-37) (HUMAN);GLP-1(7-37) impurity
CBNumber
CB1445727
Molecular Formula
C151H228N40O47
Formula Weight
3355.67
MOL File
106612-94-6.mol
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GLP-1 (7-37) Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM)
form 
Lyophilized powder
color 
White to off-white
Water Solubility 
Soluble in water at 2mg/ml
Sequence
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
CAS DataBase Reference
106612-94-6
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G9416
Product name
Glucagon-Like Peptide 1 Fragment 7-37 human
Purity
≥96% (HPLC)
Packaging
0.5mg
Price
$530
Updated
2024/03/01
Alfa Aesar
Product number
J66232
Product name
Glucagon Like Peptide-1 (7-37)
Packaging
0.5mg
Price
$191
Updated
2023/06/20
Alfa Aesar
Product number
J66232
Product name
Glucagon Like Peptide-1 (7-37)
Packaging
1mg
Price
$364
Updated
2023/06/20
Tocris
Product number
5374
Product name
GLP-1(7-37)
Packaging
1
Price
$458
Updated
2021/12/16
ChemScene
Product number
CS-5975
Product name
GLP-1(7-37)
Purity
99.87%
Packaging
5mg
Price
$432
Updated
2021/12/16
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GLP-1 (7-37) Chemical Properties,Usage,Production

Description

GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.

Uses

Glucagon-Like Peptide 1 Fragment 7-37 human has been used:

  • as a positive control for insulin secretion of pancreatic islets
  • to test its effect on insulin response in horse islets
  • in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction

General Description

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.

Biochem/physiol Actions

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.

in vitro

In vitro, truncated glucagon-like peptides [GLP-1(7-36)-amide and GLP-1(7-37)] increase insulin secretion in a glucose-dependent manner, and desensitization to the action of GLP-1(7-37) has been demonstrated acutely with high concentrations.

in vivo

GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats. Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM.

storage

Store at -20°C

GLP-1 (7-37) Preparation Products And Raw materials

Raw materials

Preparation Products

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GLP-1 (7-37) Suppliers

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View Lastest Price from GLP-1 (7-37) manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd
Product
GLP-1(7-37) 106612-94-6
Price
US $0.00/mg
Min. Order
10mg
Purity
99%
Supply Ability
1000 boxes
Release date
2023-06-27
Zibo Hangyu Biotechnology Development Co., Ltd
Product
GLP-1 (7-37) 106612-94-6
Price
US $80.00-800.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-02
Shanghai Getian Industrial Co., LTD
Product
GLP-1 (7-37) 106612-94-6
Price
US $28.00/box
Min. Order
1box
Purity
99%
Supply Ability
20000box
Release date
2024-06-03

106612-94-6, GLP-1 (7-37)Related Search:

Growth hormone releasing peptide Pralmorelin Sermorelin Nesiritide acetate Thymopentin Triptorelin acetate Pramlintide acetate Eptifibatide Thymalfasin Glucagon GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN GLP-2（Glucagon-like peptide-2） GLP-1（Glucagon-like peptide-1）(7-36) GLP-1 (7-37) GLP-1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT) AC-LEU-VAL-LYS-ALDEHYDE GLP-1+ FITC（Glucagon-like peptide-1）(7-36) ([125I]-TYR)-GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

  • Insulinotropin (human)
  • Peptide GLP-1 (human glucose-lowering peptide-1)
  • Glp-I (7-37)
  • Glucagon like peptide I (7-37)
  • Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-
  • Tglp-1
  • GLP-1, 7-37
  • Preproglucagon 78-108
  • GLP-1 (7-37) (huMan, bovine, guinea pig, Mouse, rat) Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucag
  • 7-37-Glucagon-like peptide I (human)
  • Human GLP-1 (7-37)
  • GLP-1(7-38), Insulinotropin
  • insulinotropin
  • GLP-1, 7-37, Preproglucagon 78-108
  • Glucagon-Like Peptide (GLP) I (7-37)
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • HuMan GLP-1
  • 7-37-Glucagon-likepeptide
  • H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH acetate salt
  • GLP-1 (7-37) Acetate | Glucagon-Like Peptide 1
  • l-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alany
  • PROGLUCAGON (78-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • PREPROGLUCAGON 78-108 HUMAN
  • PREPROGLUCAGON (98-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • INSULINOTROPIN (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
  • GLP-1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLP-1 (7-37) (HUMAN)
  • GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLUCAGON-LIKE PEPTIDE 1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLUCAGON LIKE PEPTIDE-I (7-37), HUMAN
  • GLUCAGON-LIKE PEPTIDE 1, FRAGMENT 7-37 HUMAN
  • GLUCAGON-LIKE PEPTIDE 1 (7-37)
  • GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN)
  • GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLP-1(7-37), >98%
  • GLP-1(7-37),HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG, >98%
  • GLP-1(7-37) impurity
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH USP/EP/BP
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GL...
  • TIANFUCHEM--106612-94-6---H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR- LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-LE-ALA-TRP-LEU-VAL- LYS-GLY-ARG-GLY-OH
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • Insulinotropin acetate [GLP-1 (7-37)
  • GLP-1 acetate salt
  • Glucagon-Like Peptide-1 (7-37)|GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)
  • (5S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S,44S,50S,53S,56S,59S,62S,65S,68S,71S,74S,77S,80S,86S)-20-((1H-Indol-3-yl)methyl)-86-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)propanamido)-44-(3-amino-3-oxopropyl)-11,35-bis(4-aminobutyl)-29,77-dibenzyl-26-((S)-sec-butyl)-32,50-bis(2-carboxyethyl)-68-(carboxymethyl)-5-(3-guanidinopropyl)-56-(4-hydroxybenzyl)-74,80-bis((R)-1-hydroxyethyl)-59,62,71-tris(hydroxymethyl)-17,53-diisobutyl-14,65-diisopropyl-23,38,41-trimethyl-4,7,10,13,16,19,22,2
  • 106612-94-6
  • C151H228N40O47
  • peptides pharm
  • peptide