2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

Product Name: 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
CAS No.: 184416-84-0
Chemical Name: 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
Synonyms: 2,3-Dichloroisonicotinic;2,3-Dichloroisonicotinicaci;2,3-dichloroisonicotic acid;2,3-DICHLOROISONICOTINIC ACID;2,3- twochlorineisonicotinic acid;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 2,3-dichloro-;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH;2,3-Dichloropyridine-4-carboxylic acid, 4-Carboxy-2,3-dichloropyridine
CBNumber: CB1447059
Molecular Formula: C6H3Cl2NO2
Formula Weight: 192
MOL File: 184416-84-0.mol

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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Property

Melting point:: 187°
Boiling point:: 413.6±40.0 °C(Predicted)
Density: 1.612±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 1.46±0.28(Predicted)
form: Solid
Appearance: Yellow to brown Solid
CAS DataBase Reference: 184416-84-0

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 724076
Product name: 2,3-Dichloropyridine-4-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $54
Updated: 2022/05/15

TRC

Product number: D438463
Product name: 2,3-DichloroisonicotinicAcid
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142844
Product name: 2,3-Dichloroisonicotinic acid
Packaging: 2g
Price: $88
Updated: 2021/12/16

AK Scientific

Product number: J98465
Product name: 2,3-Dichloroisonicotinicacid
Packaging: 10g
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 045193
Product name: 2,3-Dichloroisonicotinic acid
Purity: >95%
Packaging: 5g
Price: $100
Updated: 2021/12/16

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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

2402-77-9

124-38-9

184416-84-0

The general procedure for the synthesis of 2,3-dichloropyridine-4-carboxylic acid from 2,3-dichloropyridine and carbon dioxide was as follows: a hexane solution (31 mL, 50 mmol) of 1.6 M nBuLi was added slowly and dropwise to an anhydrous THF (100 mL) solution of diisopropylamine (7.0 mL, 50 mmol) at -25 °C under inert atmosphere. Subsequently, the reaction mixture was cooled to -78 °C and 2,3-dichloropyridine was added. The reaction mixture was kept stirred at -78 °C for 3 h. It was then poured into solid carbon dioxide and aged for 18 h at room temperature. After the reaction was completed, the mixture was diluted with water (100 mL), washed with ether (3 x 40 mL), then cooled to 0°C and acidified with concentrated HCl (about 5 mL). The acidified mixture was extracted with ether (3 x 50 mL), the organic extracts were combined, dried with anhydrous Na2SO4, filtered and concentrated to give 2,3-dichloropyridine-4-carboxylic acid as a white solid (7.7 g, 80% yield). The product was characterized by 1H NMR (d6-DMSO, 400 MHz): δ 8.49 (d, J = 5.0 Hz, 1H), 7.72 (d, J = 5.0 Hz, 1H).

References

[1] European Journal of Organic Chemistry, 2001, # 7, p. 1371 - 1376
[2] Patent: WO2009/85980, 2009, A1. Location in patent: Page/Page column 46

2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Suppliers

China 130 Germany 2 India 2 United Kingdom 4 United States 15 Global 153

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View Lastest Price from 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID manufacturers

PNP Biotech Co. Ltd

Product: 2,3-Dichloroisonicotinic acid 184416-84-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-12

Dideu Industries Group Limited

Product: 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-03

Career Henan Chemical Co

Product: 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kGS
Release date: 2018-12-14

184416-84-0, 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACIDRelated Search:

5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid,5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID,5,6-Dichloropyridine-3-carboxylic acid, 98+% 2,6-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 2,4-Dichloropyridine-3-carboxylic acid 3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID,3,6-dichloropyridine-2-carboxylic acid clopyralid,DICHLOROPYRIDINE ACID [3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID ] 2,5-DICHLOROPYRIDINE-3-CARBOXYLIC ACID 3,5-DICHLOROPYRIDINE-2-CARBOXYLIC ACID 3-Amino-2,6-dichloro-isonicotinic acid ethyl ester 2,5-DICHLOROISONICOTINIC ACID / 2,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID,2,5-Dichloropyridine-4-carboxylic acid ,97%,2,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID,2,4-DICHLOROPYRIDINE-5-CARBOXYLIC ACID 2-BROMO-3,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 3,5-Dichloropyridine-4-carboxylic acid methyl ester, Methyl 3,5-dichloroisonicotinate 2,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID 2,6-Dichloropyridine-4-carboxylic acid methyl ester 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 3-Amino-2,6-dichloropyridine-4-carboxylic acid methyl ester Clopyralid (2-hydroxyethyl)ammonium 3,5-Dichloroisonicotinic acid(3,5-Dichloropyridine-4-carboxylic acid),3,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

2,3-Dichloroisonicotinic

2,3-DICHLOROISONICOTINIC ACID

2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

2,3-dichloroisonicotic acid

2,3-Dichloropyridine-4-carboxylic acid, 4-Carboxy-2,3-dichloropyridine

2,3- twochlorineisonicotinic acid

4-Pyridinecarboxylic acid, 2,3-dichloro-

2,3-Dichloroisonicotinicaci

2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH

184416-84-0

Pyridines

intermediate