3-(Chlorosulfonyl)benzoic acid

Product Name: 3-(Chlorosulfonyl)benzoic acid
CAS No.: 4025-64-3
Chemical Name: 3-(Chlorosulfonyl)benzoic acid
Synonyms: AKOS BB-9469;AKOS BBS-00006994;RARECHEM AL BO 0793;TIMTEC-BB SBB003351;3-(Chlorosulfonyl)be;3-Chlorosulfony benzoic acid;3-(chlorosulfonyl)-benzoicaci;3-(CHLOROSULFONYL)BENZOIC ACID;3-(CHLOROSULPHONYL)BENZOIC ACID;M-(CHLOROSULFONYL) BENZOIC ACID
CBNumber: CB1476213
Molecular Formula: C7H5ClO4S
Formula Weight: 220.63
MOL File: 4025-64-3.mol

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3-(Chlorosulfonyl)benzoic acid Property

Melting point:: 128-130 °C(lit.)
Boiling point:: 402.5±28.0 °C(Predicted)
Density: 1.591±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 3.00±0.10(Predicted)
color: White to Brown
Sensitive: Moisture Sensitive
BRN: 2645465
CAS DataBase Reference: 4025-64-3(CAS DataBase Reference)
NIST Chemistry Reference: M-(chlorosulfonyl)benzoic acid(4025-64-3)
EPA Substance Registry System: Benzoic acid, 3-(chlorosulfonyl)- (4025-64-3)

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Safety

Hazard Codes: C
Risk Statements: 34-29-22
Safety Statements: 26-27-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
TSCA: Yes
HazardClass: 8
PackingGroup: II
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 441759
Product name: 3-(Chlorosulfonyl)benzoic acid
Purity: 95%
Packaging: 5g
Price: $25.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 441759
Product name: 3-(Chlorosulfonyl)benzoic acid
Purity: 95%
Packaging: 25g
Price: $86.1
Updated: 2025/07/31

TCI Chemical

Product number: C3466
Product name: 3-(Chlorosulfonyl)benzoic Acid
Packaging: 5G
Price: $28
Updated: 2025/07/31

TCI Chemical

Product number: C3466
Product name: 3-(Chlorosulfonyl)benzoic Acid
Packaging: 25G
Price: $112
Updated: 2025/07/31

TRC

Product number: C384970
Product name: 3-(Chlorosulfonyl)benzoic Acid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

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3-(Chlorosulfonyl)benzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light beige crystalline powder

General Description

3-(Chlorosulfonyl)benzoic acid is a sulfonyl halide. It participates in the synthesis of novel anthranilic acid class of PPARδ (Peroxisome proliferator-activated receptor δ) partial agonists.

Synthesis

65-85-0

4025-64-3

1.22 g (10 mmol) of benzoic acid was accurately weighed into a 50 mL pear shaped flask and 10 mL of chlorosulfonic acid was slowly added. The reaction mixture was stirred at 100°C for 45 minutes. Upon completion of the reaction, the reaction solution was slowly added dropwise to ice brine followed by vacuum filtration. The resulting solid was washed with cold water and finally dried under vacuum to obtain 3-chlorosulfonylbenzoic acid in white solid form in 88.7% yield.

References

[1] Patent: CN105732444, 2016, A. Location in patent: Paragraph 0031; 0032; 0036; 0037; 0038
[2] Patent: WO2014/100833, 2014, A1. Location in patent: Paragraph 0076
[3] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 961 - 965
[4] Patent: US2005/49307, 2005, A1. Location in patent: Page/Page column 5
[5] European Journal of Medicinal Chemistry, 2014, vol. 89, p. 503 - 523

3-(Chlorosulfonyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(Chlorosulfonyl)benzoic acid Suppliers

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View Lastest Price from 3-(Chlorosulfonyl)benzoic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-(Chlorosulfonyl)benzoic acid 4025-64-3
Price: US $0.00-0.00/KG
Min. Order: 10mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-19

Career Henan Chemical Co

Product: 3-(Chlorosulfonyl)benzoic acid 4025-64-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 97%
Supply Ability: 1000kg
Release date: 2018-12-18

4025-64-3, 3-(Chlorosulfonyl)benzoic acidRelated Search:

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3-(Chlorosulfonyl)Benzoic Acid UN 3261

3-(Chlorosulfonyl)benzoic acid ,97%

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3-(CHLOROSULFONYL)BENZOIC ACID, 98+%

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3-(Chlorosulfonyl)be

4025-64-3

C7H5ClO4S

C7H5O4ClS

ClSO2C6H4CO2H

SULFONYL CHLORIDE

Organic Building Blocks

Sulfur Compounds

Sulfonyl Halides

Building Blocks

Fluorobenzene

Benzene derivates

Organic Building Blocks

Sulfonyl Halides

Sulfur Compounds

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