SRI 31215

Product Name: SRI 31215
CAS No.: 1832686-44-8
Chemical Name: SRI 31215
Synonyms: SRI 31215;SRI31215 2TFA;SRI-31215 2TFA;SRI 31215 2TFA;SRI-31215 Bis-TFA salt;SRI 31215 TFA, 10 mM in DMSO;SRI31215,c-Met/HGFR,SRI-31215,SRI 31215 TFA,inhibit,Inhibitor;SRI31215 2TFA; SRI-31215 2TFA; SRI 31215 2TFA; SRI-31215 BIS-TFA SALT; SRI 31215 BIS-TFA SALT; SRI31215 BIS-TFA SALT;3-(3-((1-Benzylpiperidin-4-yl)methyl)-5-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)benzimidamide 2,2,2-trifluoroacetate
CBNumber: CB14858176
Molecular Formula: C27H34F3N5O3
Formula Weight: 533.6
MOL File: 1832686-44-8.mol

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SRI 31215 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: Light yellow to khaki

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0083769
Product name: SRI31215TFA
Purity: 99.06%
Packaging: 5mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0083769
Product name: SRI31215TFA
Purity: 99.06%
Packaging: 10mg
Price: $280
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0009822
Product name: SRI-31215 TFA
Purity: 95.00%
Packaging: 5MG
Price: $452.2
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573469
Product name: SRI31215 2TFA
Purity: >98%
Packaging: 100mg
Price: $912.9
Updated: 2021/12/16

ChemScene

Product number: CS-0083769
Product name: SRI31215TFA
Purity: 99.06%
Packaging: 50mg
Price: $980
Updated: 2021/12/16

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SRI 31215 Chemical Properties,Usage,Production

Uses

SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer[1].

References

[1] Owusu BY, et al. Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling. Oncotarget. 2016 May 17;7(20):29492-506. DOI:10.18632/oncotarget.8785

SRI 31215 Preparation Products And Raw materials

Raw materials

Preparation Products

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SRI 31215 Suppliers

China 36 United States 4 Global 40

Sichuan Wei Keqi Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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1832686-44-8, SRI 31215Related Search:

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SRI 31215

SRI 31215 2TFA

SRI31215 2TFA

SRI-31215 2TFA

SRI31215 2TFA; SRI-31215 2TFA; SRI 31215 2TFA; SRI-31215 BIS-TFA SALT; SRI 31215 BIS-TFA SALT; SRI31215 BIS-TFA SALT

SRI-31215 Bis-TFA salt

SRI31215,c-Met/HGFR,SRI-31215,SRI 31215 TFA,inhibit,Inhibitor

SRI 31215 TFA, 10 mM in DMSO

3-(3-((1-Benzylpiperidin-4-yl)methyl)-5-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)benzimidamide 2,2,2-trifluoroacetate

1832686-44-8