SR 0987

Product Name: SR 0987
CAS No.: 303126-97-8
Chemical Name: SR 0987
Synonyms: SR 0987;SR0987 >=98% (HPLC);SR 0987;SR-0987;SR0987;303126-97-8;SR0987,ROR,SR-0987,Inhibitor,SR 0987,inhibit,RAR-related orphan receptor;2-chloro-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)benzamide;2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide;Benzamide, 2-chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
CBNumber: CB13152747
Molecular Formula: C16H10ClF6NO2
Formula Weight: 397.7
MOL File: 303126-97-8.mol

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SR 0987 Property

Boiling point:: 378.8±42.0 °C(Predicted)
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)
pka: 9.22±0.15(Predicted)
form: solid
color: White
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19503
Product name: SR 0987
Purity: ≥98%
Packaging: 1mg
Price: $27
Updated: 2024/03/01

Cayman Chemical

Product number: 19503
Product name: SR 0987
Purity: ≥98%
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 19503
Product name: SR 0987
Purity: ≥98%
Packaging: 10mg
Price: $122
Updated: 2024/03/01

Cayman Chemical

Product number: 19503
Product name: SR 0987
Purity: ≥98%
Packaging: 25mg
Price: $236
Updated: 2024/03/01

Tocris

Product number: 5868
Product name: SR0987
Purity: ≥98%(HPLC)
Packaging: 50
Price: $704
Updated: 2021/12/16

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SR 0987 Chemical Properties,Usage,Production

Description

SR 0987 is an agonist of the T cell-specific isoform of RORγ (RORγt, retinoic acid receptor-related orphan receptor-γt), inducing reporter gene expression with an EC₅₀ value of ~800 nM. Stimulation of mouse EL4 T lymphocytes with SR 0987, following activation with PMA and ionomycin , increases expression of the RORγt target IL-17, while expression of the programmed cell death protein PD-1 is decreased and granzyme B is unchanged. Decreased cell surface PD-1 protein, assessed by flow cytometry, is observed in a variety of T cells treated with SR 0987.

Uses

SR 0987 is a RORγt agonist.

storage

Store at +4°C

References

1) Chang?et al.?(2016),?Synthetic RORγt Agonists Enhance Protective Immunity;?ACS Chem. Biol.?11?1012

SR 0987 Preparation Products And Raw materials

Raw materials

Preparation Products

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SR 0987 Suppliers

China 38 India 1 United Kingdom 1 United States 8 USA 1 Global 49

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7266
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1847
Advantage: 55

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1990
Advantage: 58

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1990
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-66110311 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15527
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

303126-97-8, SR 0987Related Search:

2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide 4-Quinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo- NA SR-717 SRT3025 SR9009 SR19881 SR-9243 SRPK inhibitor SR 1078 N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide SRI 31215 SR27897 SR17018 N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine SR8278 SR-4835 SR18662

SR 0987

2-chloro-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)benzamide

2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide

SR 0987;SR-0987;SR0987;303126-97-8

Benzamide, 2-chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-

SR0987 >=98% (HPLC)

SR0987,ROR,SR-0987,Inhibitor,SR 0987,inhibit,RAR-related orphan receptor

303126-97-8

C16H10ClF6NO2

API