ChemicalBook > CAS DataBase List > SR19881
SR19881
- Product Name
- SR19881
- CAS No.
- 2213490-89-0
- Chemical Name
- SR19881
- Synonyms
- SR19881;SR 19881, 10 mM in DMSO;N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide;Benzamide, N-[2-[4-(diethylamino)phenyl]ethyl]-4-hydroxy-;SR-19881,estrogen-related receptor,nuclear receptor,amide,SR19881,phenol,ligand binding domain (LBD),inhibit,SR 19881,Inhibitor,Estrogen Receptor/ERR,diethylamine variant
- CBNumber
- CB35839813
- Molecular Formula
- C19H24N2O2
- Formula Weight
- 312.41
- MOL File
- 2213490-89-0.mol
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SR19881 Property
- Boiling point:
- 540.8±40.0 °C(Predicted)
- Density
- 1.130±0.06 g/cm3(Predicted)
- pka
- 8.52±0.15(Predicted)
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SR19881 Chemical Properties,Usage,Production
Uses
SR19881 is a potent dual agonist of ERRγ and ERRβ, with EC50 values of 0.39 and 0.63 μM, respectively[1].
IC 50
ERRγ: 0.39 μM (EC50); ERRβ: 0.63 μM (EC50)
References
[1] Lin H, et al. Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists. Bioorg Med Chem Lett. 2018;28(8):1313-1319. DOI:10.1016/j.bmcl.2018.03.019
SR19881 Preparation Products And Raw materials
Raw materials
Preparation Products
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