Metrizoic acid
- Product Name
- Metrizoic acid
- CAS No.
- 1949-45-7
- Chemical Name
- Metrizoic acid
- Synonyms
- Metrizoic;metrizoate;Triosil-280;METRIZOIC ACID;MetrizoicAcid>Metrizoic acid USP/EP/BP;3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido);3,5-DiacetaMido-N-Methyl-2,4,6-triiodobenzoic Acid;3-acetamido-2,4,6-triiodo-5-N-methylacetamidobenzoic acid;3-acetamido-2,4,6-triiodo-5-(n-methylacetamido)-benzoicaci
- CBNumber
- CB1775662
- Molecular Formula
- C12H11I3N2O4
- Formula Weight
- 627.94
- MOL File
- 1949-45-7.mol
Metrizoic acid Property
- Melting point:
- 281-282°
- Boiling point:
- 678.8±55.0 °C(Predicted)
- Density
- 2.3140 (estimate)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO
- form
- Solid
- pka
- 0.82±0.10(Predicted)
- color
- White
- Merck
- 14,6156
- CAS DataBase Reference
- 1949-45-7(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 3-(acetylamino)-5-(acetylmethylamino)-2,4,6-triiodo- (1949-45-7)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- RTECS
- DG0887300
- HS Code
- 2924.29.7790
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M1363
- Product name
- Metrizoic Acid
- Purity
- >98.0%(T)(HPLC)
- Packaging
- 5g
- Price
- $31
- Updated
- 2024/03/01
- Product number
- M1363
- Product name
- Metrizoic Acid
- Purity
- >98.0%(T)(HPLC)
- Packaging
- 25g
- Price
- $59
- Updated
- 2024/03/01
- Product number
- M338935
- Product name
- Metrizoic Acid
- Packaging
- 10g
- Price
- $950
- Updated
- 2021/12/16
- Product number
- 41633
- Product name
- Metrizoic Acid
- Packaging
- 10g
- Price
- $1460
- Updated
- 2021/12/16
- Product number
- CHM0030393
- Product name
- METRIZOIC ACID
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $2148.3
- Updated
- 2021/12/16
Metrizoic acid Chemical Properties,Usage,Production
Originator
Isopaque,Winthrop,France,1973
Uses
Diagnosis aid (radiopaque medium).
Definition
ChEBI: Metrizoic acid is a monocarboxylic acid. It has a role as a radioopaque medium.
Manufacturing Process
3,5-Diacetamido-2,4,6-triiodobenzoic acid (diatrizoic acid) (see Diatrizoate entry for synthesis) (10 g) is suspended in water (10 ml), 5 N potassium hydroxide (4.3 equivalent) is added and the mixture cooled to about 15°C. Dimethyl sulfate (0.5 equivalent) dissolved in an equal volume of acetone is added drop by drop while stirring. After the reaction mixture has been stirred for about 1 hour hydrochloric acid (1:1) is added, with stirring to pH about 0.5. The precipitate is filtered, washed and suspended moist in 4 parts of water, concentrated ammonia is added to pH about 7 and the ammonium salt solution is isomerized at 90°C to 100°C for about one-half hour whereafter additional ammonia is added to pH about 9 followed by solid ammonium chloride (about 10% weight/volume) and the solution stirred overnight and the excess of 3,5-diacetamide-2,4,6-triiodobenzoic acid recovered as ammonium salt on the filter. The filtrate is precipitated by means of hydrochloric acid (1:1 ) at pH about 0.5 and the N-methyl-3,5-diacetamido- 2,4,6-triiodobenzoic acid collected on a filter, washed and dried.
Therapeutic Function
Diagnostic aid (radiopaque medium)
Metrizoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Metrizoic acid manufacturers
- Product
- Metrizoic acid 1949-45-7
- Price
- US $350.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 9000kg/per week
- Release date
- 2021-09-10