ChemicalBook > CAS DataBase List > 3,5-Dimethyl-4-methoxybenzoic acid
3,5-Dimethyl-4-methoxybenzoic acid
- Product Name
- 3,5-Dimethyl-4-methoxybenzoic acid
- CAS No.
- 21553-46-8
- Chemical Name
- 3,5-Dimethyl-4-methoxybenzoic acid
- Synonyms
- TB023;3,5-DIMETHYL ANISIC ACID;3,5-DIMETHYL-4-ANISIC ICD;3,5-DIMETHYL-P-ANISIC ACID;3,5-DIMETHYL-4-ANISIC ACID;3,5-Dimethyl-4-Methoxybenzoic;4-methoxy-3,5-dimethylbenzoate;3,5-Dimethyl-p-anisic acid,98%;3,5-DIMETHYL-P-ANISIC ACID 98%;,5-diMethyl-4-Methoxybenzoic acid
- CBNumber
- CB1780569
- Molecular Formula
- C10H12O3
- Formula Weight
- 180.2
- MOL File
- 21553-46-8.mol
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3,5-Dimethyl-4-methoxybenzoic acid Property
- Melting point:
- 191-195 °C (lit.)
- Boiling point:
- 253.02°C (rough estimate)
- Density
- 1.1185 (rough estimate)
- refractive index
- 1.5392 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 4.61±0.10(Predicted)
- form
- Crystalline Solid
- color
- White to brown
- CAS DataBase Reference
- 21553-46-8(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 638692
- Product name
- 3,5-Dimethyl-4-methoxybenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $87.4
- Updated
- 2022/05/15
Sigma-Aldrich
- Product number
- 638692
- Product name
- 3,5-Dimethyl-4-methoxybenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $192
- Updated
- 2022/05/15
TCI Chemical
- Product number
- M2139
- Product name
- 4-Methoxy-3,5-dimethylbenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $40
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2139
- Product name
- 4-Methoxy-3,5-dimethylbenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $112
- Updated
- 2025/07/31
TRC
- Product number
- D474985
- Product name
- 3,5-Dimethyl-4-methoxybenzoic acid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
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3,5-Dimethyl-4-methoxybenzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to brown crystalline solid
Synthesis
152775-45-6
21553-46-8
General procedure for the synthesis of 3,5-dimethyl-4-methoxybenzoic acid from 4-methoxy-3,5-dimethylbenzenecarbonitrile: 4-methoxy-3,5-dimethylbenzenecarbonitrile (1664 mg) was suspended in ethanol (32 mL), to which 8M NaOH solution (163 mL) was added. The mixture was placed in a pressure reactor and the reaction was stirred at 120 °C overnight. Upon completion of the reaction, ethanol was removed by rotary evaporation. Water was added to the residue and the aqueous solution was washed with ether to remove non-polar impurities. Subsequently, the aqueous layer was acidified with concentrated hydrochloric acid to pH < 2, at which point the target product precipitated as a solid. The acidified aqueous layer was extracted with ethyl acetate and the organic phases were combined and washed sequentially with water and saturated brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated to afford 3,5-dimethyl-4-methoxybenzoic acid as a white solid in 99% yield.LRMS (m/z): 181 ([M+H]+).HPLC retention time: 5.52 min (Method B).
References
[1] Patent: WO2011/144338, 2011, A1. Location in patent: Page/Page column 92
[2] Patent: EP2390252, 2011, A1. Location in patent: Paragraph 0449; 0450
3,5-Dimethyl-4-methoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dimethyl-4-methoxybenzoic acid manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 3,5-Dimethyl-4-methoxybenzoic acid 21553-46-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-02
Honest Joy Holdings Limited
- Product
- 3,5-Dimethyl-4-methoxybenzoicacid 21553-46-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
Career Henan Chemical Co
- Product
- 3,5-Dimethyl-4-methoxybenzoic acid 21553-46-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-30
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