ChemicalBook > CAS DataBase List > 3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL

3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL

Product Name
3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL
CAS No.
7037-30-1
Chemical Name
3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL
Synonyms
1-METHYL-4-PIPERIDINEPROPANOL;4-N-Methyl piperidine propanol;4-Piperidinepropanol, 1-methyl-;3-(1-methyl-4-piperidyl)propan-1-ol;4-(3-Hydroxypropyl)-1-methylpiperidine;3-(1-methyl-4-piperidyl)propan-1-ol - [M87281]
CBNumber
CB21010183
Molecular Formula
C9H19NO
Formula Weight
157.25
MOL File
7037-30-1.mol
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3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL Property

Boiling point:
114-116 °C(Press: 4 Torr)
Density 
0.929±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
15.16±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0009592
Product name
3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL
Purity
95.00%
Packaging
5MG
Price
$496.49
Updated
2021/12/16
Crysdot
Product number
CD11069698
Product name
3-(1-Methylpiperidin-4-yl)propan-1-ol
Purity
95+%
Packaging
250mg
Price
$63
Updated
2021/12/16
Chemenu
Product number
CM116546
Product name
4-(3-Hydroxypropyl)-1-methylpiperidine
Purity
95%
Packaging
1g
Price
$163
Updated
2021/12/16
Abosyn
Product number
61-10081
Product name
3-(1-Methylpiperidin-4-yl)propan-1-ol
Purity
95-98%
Packaging
1g
Price
$405
Updated
2021/12/16
Chemenu
Product number
CM116546
Product name
4-(3-Hydroxypropyl)-1-methylpiperidine
Purity
95%
Packaging
5g
Price
$673
Updated
2021/12/16
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3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL Chemical Properties,Usage,Production

Synthesis

154775-43-6

7037-30-1

General procedure for the synthesis of 3-(1-methylpiperidin-4-yl)-1-propanol from 1-N-BOC-4-piperidinepropionic acid: A. Synthesis of 3-(1-methylpiperidin-4-yl)-propan-1-ol. To a tetrahydrofuran (THF) solution (40 mmol) of 1N lithium aluminum hydride, a THF solution (30 mL) of N-BOC-4-piperidinepropionic acid (3.0 g, 11.6 mmol) was added slowly and dropwise under reflux conditions. The reaction mixture was heated to reflux for 3 hours and then cooled to room temperature. The mixture was further cooled to 0 °C, water (1.5 mL) was slowly added and the reaction mixture was warmed to room temperature within 15 minutes. The mixture was again cooled to 0°C and 10% sodium hydroxide solution (1.5 mL) was slowly added. After warming to room temperature within 15 minutes, the mixture was again cooled to 0°C and additional water (4.5 mL) was added. The resulting mixture was slowly warmed to room temperature over 18 hours and subsequently filtered through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure and the residue was purified by method 2 to give 1.9 g (100% yield) of 3-(1-methylpiperidin-4-yl)-propan-1-ol as a yellow oil. Mass spectrum (electrospray): calculated mass of C9H19NO, 157.15; measured value: 157.15. m/z found, 158.1 [M+H]+. 1H NMR (400MHz, CD3OD): δ 3.45-3.41(m, 2H), 2.77-2.74(m, 2H), 1.89-1.85(m, 2H), 1.64 -1.61(m, 2H), 1.47-1.43(m, 2H), 1.21-1.12(m, 5H).

References

[1] Patent: US2005/70550, 2005, A1. Location in patent: Page/Page column 16-17
[2] Patent: US2005/261309, 2005, A1. Location in patent: Page/Page column 17

3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OL Suppliers

China 18 India 1 United States 3 Global 22
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38

7037-30-1, 3-(1-METHYL-PIPERIDIN-4-YL)-PROPAN-1-OLRelated Search:

N-Benzylcinchonidinium chloride N-BENZYLCINCHONINIUM CHLORIDE Reserpine N-(4-Trifloromethybenzyl)cinchoninum bromide LAPPACONITINE HYDROBROMIDE PROTOVERATRINE A+B RESCINNAMINE 1-(2-HYDROXYETHYL)-4-(3-HYDROXYPROPYL)PIPERIDINE PROTOVERATRINE A Aconitine VERATRIDINE Sinomenine METHYLLYCACONITINE CITRATE Deserpidine CONDELPHINE SYROSINGOPINE PROTOVERATRINE B Cevadine

  • 4-N-Methyl piperidine propanol
  • 1-METHYL-4-PIPERIDINEPROPANOL
  • 4-(3-Hydroxypropyl)-1-methylpiperidine
  • 4-Piperidinepropanol, 1-methyl-
  • 3-(1-methyl-4-piperidyl)propan-1-ol
  • 3-(1-methyl-4-piperidyl)propan-1-ol - [M87281]
  • 7037-30-1
  • Heterocycle-other series