ChemicalBook > CAS DataBase List > Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Product Name
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
CAS No.
5909-24-0
Chemical Name
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
Synonyms
4-Chloro-5-ethoxycarbonyl-2-methylthiopyrimidine;ethyl 4-chloro-2-methylthio-5-pyrimidine-carboxyl;4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester;NSC 123534;SIEHE AV22429;BUTTPARK 45\03-53;Avanafil Impurity 69;Ethyl4-chloro-2-met...;thio-5-pyrimidinecarboxyL;4-Chloro-2-methylsulfanyl-
CBNumber
CB2141204
Molecular Formula
C8H9ClN2O2S
Formula Weight
232.69
MOL File
5909-24-0.mol
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Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Property

Melting point:
60-63 °C (lit.)
Boiling point:
132°C/0.4mmHg(lit.)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate
pka
-2.19±0.29(Predicted)
form 
Crystalline Powder
color 
White to light yellow to beige
InChI
InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3
InChIKey
SNNHLSHDDGJVDM-UHFFFAOYSA-N
SMILES
C1(SC)=NC=C(C(OCC)=O)C(Cl)=N1
CAS DataBase Reference
5909-24-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
IRRITANT, KEEP COLD
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
145963
Product name
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
Purity
98%
Packaging
5g
Price
$22.8
Updated
2024/03/01
Sigma-Aldrich
Product number
145963
Product name
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
Purity
98%
Packaging
25g
Price
$54.24
Updated
2024/03/01
TCI Chemical
Product number
E0841
Product name
Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate
Purity
>97.0%(GC)
Packaging
5g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
E0841
Product name
Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate
Purity
>97.0%(GC)
Packaging
25g
Price
$106
Updated
2024/03/01
Alfa Aesar
Product number
B22429
Product name
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%
Packaging
5g
Price
$43.65
Updated
2024/03/01
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Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Chemical Properties,Usage,Production

Chemical Properties

off white to light yellow solid

Uses

A pyrimidine derivative as inhibitor of Streptococcus faecium, Lactobacillus casei, and Pediococcus cerevisiae

Uses

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate was used in the synthesis of pyrimidinopyridones, potential inhibitors of the FMS tyrosine kinase.

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Preparation Products And Raw materials

Raw materials

Ethanol Acetic anhydride Potassium hydroxide Diethyl ethoxymethylenemalonate Triethyl orthoformate Sodium Phosphorus oxychloride Benzene 2-Methyl-2-thiopseudourea sulfate Diethyl malonate Thionyl chloride

Preparation Products

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Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Suppliers

Americas 1 Canada 2 China 382 Europe 2 France 2 Germany 6 India 18 Japan 2 Slovakia 1 Switzerland 2 United Kingdom 18 United States 45 Global 481
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
Discovery Fine Chemicals
Tel
--
Fax
--
Country
Europe
ProdList
1780
Advantage
38
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View Lastest Price from Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5909-24-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-12
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5909-24-0
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500 KG
Release date
2021-06-10
Hebei Dangtong Import and export Co LTD
Product
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5909-24-0
Price
US $100.00-60.00/kg
Min. Order
100kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-06

5909-24-0, Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylateRelated Search:

Ethyl 2-chloroacetoacetate ISOMETHIOZIN ISOXADIFEN-ETHYL Ethylparaben Ethyl acetate Ethanol Ethyl chloroacetate Ethyl cyanoacetate Ethyl acrylate ethyl 4-chloro-8-nitroquinoline-3-carboxylate 4-Chloro-5-methylpyrimidine 5-Pyrimidinemethanol ETHYL 5-PYRIMIDINECARBOXYLATE 98 Ethyl chloroformate 2-Mercaptopyrimidine 5-Pyrimidinecarboxylic acid Pyrimidine-5-carboxaldehyde 2-(Methylthio)-5-pyrimidinecarboxylic acid ethyl ester

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  • SIEHE AV22429
  • ETHYL 4-CHLORO-2-METHYLTHIO-5-PYRIMIDIN&
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  • 4-CHLORO-2-METHYLTHIO-5-PYRIMIDINE-CARBOXYLATE
  • 4-Chloro-(2-methylthio)-5-pyrimidinecarboxylic acid ethyl ester
  • 2-Methylsulfanyl-4-chloropyrimidine-4-carboxylic acid ethyl ester
  • Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate ,97%
  • Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylat
  • Ethyl 4-chloro-2-(Methyls...
  • 4-Chloro-2-methane-sulfanylpyrimidine-5-carboxylic Acid Ethyl Ester
  • NSC 123534
  • 5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
  • 2-(Methylthio)-4-chloropyrimidine-5-carboxylic acid ethyl ester
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  • thio-5-pyrimidinecarboxyL
  • Avanafil Impurity 69
  • Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate ISO 9001：2015 REACH
  • Avanafil intermediates，ethyl 4-chloro-2-methylthio-5- pyrimidine-carboxyl
  • RSSYY(Lurasidone Hydrochloride)-7
  • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate (Avanafil Impurity)
  • 4-Chloro-2-methylthiopyrimidin-5-carboxylic acid ethyl ester
  • 5909-24-0
  • 5924-24-0
  • 5929-24-0
  • C8H9ClN2O2S
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyrimidines
  • Pyrimidines
  • Nucleotides and Nucleosides
  • APIs & Intermediate
  • Pyrimidine
  • Heterocycle-Pyrimidine series
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Sulfur & Selenium Compounds
  • Building Blocks