Polyinosinic-polycytidylic acid sodium salt

Product Name: Polyinosinic-polycytidylic acid sodium salt
CAS No.: 42424-50-0
Chemical Name: Polyinosinic-polycytidylic acid sodium salt
Synonyms: Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
CBNumber: CB2187556
Molecular Formula: C19H27N7O16P2
Formula Weight: 671.41
MOL File: 42424-50-0.mol

More

Less

Polyinosinic-polycytidylic acid sodium salt Property

storage temp.: −20°C
solubility: H2O: soluble10mg/mL
form: lyophilized powder
color: White to off-white
Water Solubility: Water : 10 mg/mL (Need ultrasonic and warming)

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TR0175000

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0913
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: ≥99% (less than 1% free nucleotides, TLC)
Packaging: 10mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: P0913
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: ≥99% (less than 1% free nucleotides, TLC)
Packaging: 50mg
Price: $457
Updated: 2024/03/01

Sigma-Aldrich

Product number: 528906
Product name: Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded - CAS 42424-50-0 - Calbiochem
Purity: Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0.
Packaging: 10MG
Price: $115
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1530
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: TLR ligand tested
Packaging: 25mg
Price: $210
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1530
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: TLR ligand tested
Packaging: 100mg
Price: $627
Updated: 2024/03/01

More

Less

Polyinosinic-polycytidylic acid sodium salt Chemical Properties,Usage,Production

Uses

Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist.

Uses

TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Biological Activity

Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.

storage

Store at -20°C

Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Polyinosinic-polycytidylic acid sodium salt Suppliers

China 105 Germany 1 Switzerland 1 United Kingdom 1 United States 10 USA 1 Global 119

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

More

Less

View Lastest Price from Polyinosinic-polycytidylic acid sodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na; 42424-50-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 90.0%Min. HPLC
Supply Ability: 1000kg
Release date: 2024-09-10

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Polyinosinic-polycytidylic acid sodium salt 42424-50-0
Price: US $0.00/g
Min. Order: 1g
Purity: 45%-55%
Supply Ability: 10kg/month
Release date: 2021-09-28

Career Henan Chemica Co

Product: POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT 42424-50-0
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20 tons
Release date: 2020-11-12

42424-50-0, Polyinosinic-polycytidylic acid sodium saltRelated Search:

METHYL ISOCYANOACETATE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TERT-BUTYL ISOCYANIDE Ethyl isocyanoacetate COBALT(II) ACETYLACETONATE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ferric acetylacetonate Benzyl isocyanide Aluminum acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide N-BUTYLISOCYANIDE Cupric acetylacetonate 2,4-PENTANEDIONE, SILVER DERIVATIVE Polyinosinic acid

POLYINOSINIC ACID + POLYCYTIDYLIC ACID, SODIUM SALT

Polymyocyte sodium salt

POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT

POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT

POLY I POLY C, NA

POLY[I] POLY[C] SODIUM SALT

Oligochitosan-kanamycin-polyI-polyC sodium salt compound solution

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded

Polyinosinic Acid . Polycytidylic Acid, Sodium Salt, Double

polyinosinic-polycytidylic acid sodium

Polyinosinic–polycytidylic Acid Sodium Salt（Poly I:C ）

polyI-polyC sodium salt compound solution

Poly(I:C) sodium

POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT USP/EP/BP

Polyi polycytidylic acid sodium salt(Poly I:C) (PIC)

Poly (I:C) Na

Polyinosinicacid-polycytidylicacidsodiumsal

Polyinosinic-polycytidylic acid sodium salt gamma-irradiated

42424-50-0

BioChemical

Biochemicals and Reagents

Synthetic Oligonucleotides and Related Reagents

Nucleosides, Nucleotides, Oligonucleotides

Biochemicals and Reagents

Biomaterials

Cell Culture

Materials Science

Nucleosides

Nucleotides

Oligonucleotide Polymers and Copolymers

Oligonucleotides

Other adjuvants

Synthetic Oligonucleotides and Related Reagents

Vaccine Adjuvants

Vaccine Production

Nucleoside Mono