Methyl 3-aminocrotonate

Product Name: Methyl 3-aminocrotonate
CAS No.: 14205-39-1
Chemical Name: Methyl 3-aminocrotonate
Synonyms: Methyl (Z)-3-Aminobut-2-enoate;3-Aminocrotonate;(Z)-Methyl 3-aMinobut-2-enoate;methyl (E)-3-aminobut-2-enoate;3-Amino-but-2-enoic acid methyl ester;PALO-012;Nifedipine-4;Methyl 3-aminocroton;Nifedipine Impurity 5;Methyl 3-aminocrotote
CBNumber: CB2222855
Molecular Formula: C5H9NO2
Formula Weight: 115.13
MOL File: 14205-39-1.mol

More

Less

Methyl 3-aminocrotonate Property

Melting point:: 81-83 °C(lit.)
Boiling point:: 112°C 42mm
Density: 1.1808 (rough estimate)
vapor pressure: 2.79-2.853hPa at 25℃
refractive index: 1.4538 (estimate)
Flash point:: 91 °C
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: 18g/l
form: Crystalline Powder
pka: 5.27±0.70(Predicted)
color: White to slightly yellow
PH: 8-9 (18g/l, H2O, 20℃)
Water Solubility: insoluble
Sensitive: Hygroscopic
BRN: 956592
InChIKey: XKORCTIIRYKLLG-ONEGZZNKSA-N
LogP: -0.27 at 25℃
CAS DataBase Reference: 14205-39-1(CAS DataBase Reference)
EPA Substance Registry System: 2-Butenoic acid, 3-amino-, methyl ester (14205-39-1)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 37/39-26-24/25
WGK Germany: 3
RTECS: EM9092500
TSCA: Yes
HS Code: 29224995

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 129712
Product name: Methyl 3-aminocrotonate
Purity: 97%
Packaging: 100g
Price: $54.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 129712
Product name: Methyl 3-aminocrotonate
Purity: 97%
Packaging: 500g
Price: $54.8
Updated: 2024/03/01

TCI Chemical

Product number: A1001
Product name: Methyl 3-Aminocrotonate
Purity: >98.0%(T)
Packaging: 25g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: A1001
Product name: Methyl 3-Aminocrotonate
Purity: >98.0%(T)
Packaging: 500g
Price: $90
Updated: 2024/03/01

Alfa Aesar

Product number: B24953
Product name: Methyl 3-aminocrotonate, 97%
Packaging: 500g
Price: $95.3
Updated: 2024/03/01

More

Less

Methyl 3-aminocrotonate Chemical Properties,Usage,Production

Chemical Properties

Crystals, yellowish-white

Uses

Methyl 3-aminocrotonate is used as intermediate for the syntheses of pharmaceuticals (e.g. 1,4-dihydropyridine derivatives) as well as for the manufacture of stabilizers and plastics. Product Data Sheet

Uses

Methyl 3-aminocrotonate (Methyl 3-amino-2-butenoate) was used to synthesize 4-aryl-1,4-dihydropyridines possessing potential calcium channel blocking activity.

Uses

Nitrendipine (N490150) metabolite. The pharmacokinetics of Nitrendipine was studied in the rat and 6 major metabolites were identified.

Preparation

3-Aminocrotonate Esters, e.g., methyl 3- aminocrotonate [14205-39-1] (3-amino-2-butenoic acid, methyl ester) can be prepared by treatment of acetoacetates with aqueous ammonia. They are mainly used in the production of a series of the dihydropyridine-type calcium antagonists.

General Description

Methyl 3-aminocrotonate undergoes waste-free solid-state cascade reaction with crystalline ninhydrin.

Flammability and Explosibility

Not classified

Methyl 3-aminocrotonate Preparation Products And Raw materials

Raw materials

Preparation Products

Benidipine Cilnidipine Isradipine Nitrendipine Felodipine Manidipine Nisoldipine Amlodipine

More

Less

Methyl 3-aminocrotonate Suppliers

Americas 1 Belgium 2 Canada 2 China 384 Europe 4 Germany 7 India 82 Italy 1 Japan 6 Slovakia 1 South Korea 2 Switzerland 6 United Kingdom 14 United States 56 Global 568

XI'AN VEDA CHEMICAL CO.,LTD

Tel: 029-88665278 13772509899
Email: sherryliu@vedachem.com
Country: China
ProdList: 46
Advantage: 58

Shanghai Chengyu Biotechnology Co., Ltd.

Tel: 021-51525055
Email: 309639130@qq.com
Country: China
ProdList: 42
Advantage: 58

Hubei Hengluyuan Technology co.ltd

Tel: 027-88188016 18717196322
Email: 1764683941@qq.com
Country: China
ProdList: 2968
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40240
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

More

Less

View Lastest Price from Methyl 3-aminocrotonate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Methyl 3-aminocrotonate 14205-39-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-15

Hebei Mojin Biotechnology Co., Ltd

Product: Methyl 3-aminocrotonate 14205-39-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-04

Hebei Guanlang Biotechnology Co., Ltd.

Product: Methyl 3-aminocrotonate 14205-39-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-08-18

14205-39-1, Methyl 3-aminocrotonateRelated Search:

FATTY ACID METHYL ESTER MIX C8-C22 4-Morpholineethanesulfonic acid METSULFURON METHYL Methyl 2-(methylamino)benzoate Methyl carbamate METHYL 4-(4-AMINOPHENYL)BUTANOATE Methyl salicylate Methyl anthranilate Methyl acetate Thiophanate-methyl Pirimiphos-methyl Tribenuron methyl Crotonic acid Methyl cinnamate Kresoxim-methyl trans-Methyl crotonate Methyl 4-aminobenzoate Methyl 4-bromocrotonate

METHYL-BETA-AMINOCROTONATE

METHYL 4-AMINOCROTONATE

METHYL 3-AMINOCROTONATE

METHYL 3-AMINO-2-BUTENOATE

AMINOCROTONIC ACID METHYL ESTER

3-AMINOCROTONATE METHYL ESTER

3-AMINOCROTONIC ACID METHYL ESTER

3-AMINO-2-BUTENOIC ACID METHYL ESTER

3-amino-2-butenoicacimethylester

3-amino-crotonicacimethylester

beta-Iminomethylbutyrate

beta-aminocrotonicacidmethylester

methyl3-aminocrotonoate

methyl 3-amino-trans-but-2-enoate

2-Butenoic acid, 3-amino-, methyl ester

Methyl β-aminobutenate

Nifedipine impurity D (EP)

Methyl (Z)-3-Aminobut-2-enoate

PALO-012

Nifedipine Impurity 5

3-Aminocrotonate

Methyl 3-iminobutyrate

Crotonic acid, 3-amino-, methyl ester

(1-Aminoethylidene)acetic acid methyl

3-Amino-2-butenoic acid methyl

Methyl 3-aminocrotonate,97%

Methyl 3-aminocroton

3-Amino-but-2-enoic acid methyl ester

Methyl 3-aMinocrotonate, 97% 100GR

Methyl 3-aMinocrotonate, 97% 500GR

Methyl 3-AMino-2-butenenoate

3-Amino-2-butenoic Acid Methyl Ester 3-Aminocrotonic Acid Methyl Ester Methyl 3-Amino-2-butenoate

(Z)-Methyl 3-aMinobut-2-enoate

methyl (E)-3-aminobut-2-enoate

Methyl 3-aminocrotonate 97%

Methyl 3-Aminocrotonate Methyl 3-Amino-2-butenoate 3-Amino-2-butenoic Acid Methyl Ester

Methyl 3-aminocrotote

Divalproex Sodium Impurity 4

Nifedipine-4

3-Methyl 3-aminocrotonate

Nifedipine Impurity D Control

Methyl 3-aminocrotonate fiona

Methyl3-Aminocrotonate&gt

Nifedipine Impurity 16 (Methyl 3-aminocrotonate)

-amino-methyl cromarate

MEHYL 3-AMINOCROTONATE

Azilsartan medoxomil impurity305

Methyl Β-Aminobutenate

Methy1 3-aminocrotonate

14205-39-1

14205-23-0

14205-34-1

14205-79-1

CH3CNH2CHCOOCH3

Aromatic Amino Acids

C2 to C5

Carbonyl Compounds

Building Blocks