1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

Product Name: 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
CAS No.: 203866-14-2
Chemical Name: 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
Synonyms: N-BOC-TRANS-4-FLUORO-L-PROLINE;N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID;Boc-trans-4-F-Pro-OH;Boc-trans-4-fluoro-Pro-OH;BOC-TRANS-4-FLUORO-L-PROLINE;N-Boc-Tran-4-Fluoro-L-proline;1-BOC-Trans-4-fluoro-L-proline;(2R,4S)-N-BOC-4-FLUORO-D-PROLINE;N-T-BOC-TRANS-4-FLUORO-L-PROLINE;(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
CBNumber: CB2312240
Molecular Formula: C10H16FNO4
Formula Weight: 233.24
MOL File: 203866-14-2.mol

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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Property

Melting point:: 115-119°C
Boiling point:: 346.0±42.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
refractive index: -69 ° (C=1, MeOH)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 3.53±0.40(Predicted)
color: White to Almost white
optical activity: [α]22/D -65.0±5°, c = 1 in chloroform
InChIKey: YGWZXQOYEBWUTH-RQJHMYQMSA-N
CAS DataBase Reference: 203866-14-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687332
Product name: N-Boc-trans-4-fluoro-L-proline
Purity: 97%
Packaging: 500mg
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: B3177
Product name: (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
Purity: >96.0%(GC)(T)
Packaging: 1g
Price: $198
Updated: 2024/03/01

TCI Chemical

Product number: B3177
Product name: (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
Purity: >96.0%(GC)(T)
Packaging: 200mg
Price: $59
Updated: 2024/03/01

Alfa Aesar

Product number: H27721
Product name: N-Boc-trans-4-fluoro-L-proline, 98%
Packaging: 250mg
Price: $71.8
Updated: 2021/12/16

Alfa Aesar

Product number: H27721
Product name: N-Boc-trans-4-fluoro-L-proline, 98%
Packaging: 1g
Price: $180
Updated: 2021/12/16

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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Suppliers

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Shanghai Xinxin Pharmaceutical Technology Co., Ltd.

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Alfa Aesar

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Energy Chemical

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View Lastest Price from 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate manufacturers

Hebei Duling International Trade Co. LTD

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $43.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 tons
Release date: 2023-03-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

203866-14-2, 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylateRelated Search:

Nr (2R,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid (2R,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid N-BOC-cis-4-fluoro-L-proline Cbz-D-Valine L-Proline D-Proline N-Boc-cis-4-Fluoro-D-Proline BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-Boc-trans-4-fluoro-L-proline methyl ester N-BOC-4,4-difluoro-L-proline BOC-TRANS-4-FLUORO-5-OXO-L-PROLINE METHYL ESTER 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID

N-BOC-TRANS-4-FLUORO-L-PROLINE

N-T-BOC-TRANS-4-FLUORO-L-PROLINE

N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE

BOC-TRANS-4-FLUORO-L-PROLINE

(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected

trans-4-Fluoro-L-proline, N-BOC protected

(2S,4R)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid

(2R,4S)-N-BOC-4-FLUORO-D-PROLINE

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid

(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid

N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline

(2S,4R)-4-FLUORO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(2R,4S)-N-Boc-trans-4-Fluoro-D-proline methyl ester

(2R,4S)-N-Boc-trans-4-Fluoro-D-proline

trans-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid

N-Boc-Tran-4-Fluoro-L-proline

Boc-trans-4-fluoro-Pro-OH

(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline N-Boc-trans-4-fluoro-L-proline

1-BOC-Trans-4-fluoro-L-proline

(2S,4R)-1-Boc-4-fluoropyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboyxlic acid

(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid

(2S,4R)-4-Fluoro-1,2-pyrrolidinedicarboxylic Acid tert-B utyl Ester

1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4R)-

(2S,4R)-N-Boc-4-fluoropyrrolidine-2-carboxy lic acid

(2S,4R)-1-(tert-Dutoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid &gt

(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylicaci

BOC-TRANS-4-FLUORO-L-PROLINE USP/EP/BP

TIANFU CHEM --BOC-TRANS-4-FLUORO-L-PROLINE

Boc-trans-4-F-Pro-OH

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

1-(tert-Butyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

203866-14-2

Carboxylic Acids (Chiral)

Chiral Building Blocks

Synthetic Organic Chemistry

Chiral Building Blocks

Heterocyclic Building Blocks

Pyrrolidines