1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

ChemicalBook > CAS DataBase List > 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

Product Name: 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
CAS No.: 203866-14-2
Chemical Name: 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
Synonyms: N-BOC-TRANS-4-FLUORO-L-PROLINE;N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID;Boc-trans-4-F-Pro-OH;Boc-trans-4-fluoro-Pro-OH;BOC-TRANS-4-FLUORO-L-PROLINE;N-Boc-Tran-4-Fluoro-L-proline;1-BOC-Trans-4-fluoro-L-proline;(2R,4S)-N-BOC-4-FLUORO-D-PROLINE;N-T-BOC-TRANS-4-FLUORO-L-PROLINE;(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
CBNumber: CB2312240
Molecular Formula: C10H16FNO4
Formula Weight: 233.24
MOL File: 203866-14-2.mol

Less

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Property

Melting point:: 115-119°C
Boiling point:: 346.0±42.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
refractive index: -69 ° (C=1, MeOH)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 3.53±0.40(Predicted)
color: White to Almost white
optical activity: [α]22/D -65.0±5°, c = 1 in chloroform
InChIKey: YGWZXQOYEBWUTH-RQJHMYQMSA-N
CAS DataBase Reference: 203866-14-2(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687332
Product name: N-Boc-trans-4-fluoro-L-proline
Purity: 97%
Packaging: 500mg
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: B3177
Product name: (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
Purity: >96.0%(GC)(T)
Packaging: 1g
Price: $198
Updated: 2024/03/01

TCI Chemical

Product number: B3177
Product name: (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
Purity: >96.0%(GC)(T)
Packaging: 200mg
Price: $59
Updated: 2024/03/01

Alfa Aesar

Product number: H27721
Product name: N-Boc-trans-4-fluoro-L-proline, 98%
Packaging: 250mg
Price: $71.8
Updated: 2021/12/16

Alfa Aesar

Product number: H27721
Product name: N-Boc-trans-4-fluoro-L-proline, 98%
Packaging: 1g
Price: $180
Updated: 2021/12/16

Less

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Suppliers

Americas 1 Canada 1 China 158 Europe 1 France 1 Germany 4 India 2 Japan 1 Switzerland 1 United Kingdom 5 United States 28 Global 203

Shanghai Xinxin Pharmaceutical Technology Co., Ltd.

Tel: 13671725141
Email: hickle@yeah.net
Country: China
ProdList: 366
Advantage: 58

Shanghai joygo pharmacetical tech., Co., Ltd.

Tel: 13621615409
Fax: QQ:3065286126, 1796903118
Email: sale1@joygooo.com
Country: China
ProdList: 109
Advantage: 50

Shanghai Neff Biotechnology Co., LTD

Tel: 14782051321
Email: market@lifebiology.cn
Country: China
ProdList: 147
Advantage: 58

Shanghai GaoLang Chemical Technology Co., Ltd.

Tel: 021-57340939 18017297327
Fax: 021-37210791
Email: sales@gaolangchemical.com
Country: China
ProdList: 888
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35906
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17987
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

SHANGHAI HOHANCE CHEMICAL CO.,LTD

Tel: 021-31115312 18217084087
Fax: 86 021 31115317
Email: mary@hohance.com
Country: China
ProdList: 139
Advantage: 62

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6854
Advantage: 65

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8618575662672 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9747
Advantage: 57

Changzhou Joyous Chemical Co., Ltd.

Tel: 0519-85607258
Fax: 0519-85607278
Email: sales@joyouschem.com
Country: China
ProdList: 296
Advantage: 60

Shanghai LiangYi Fine Chemicals Co., Ltd.

Tel: 021-62594801
Fax: 021-62145414
Email: shliangyi@liangyichem.com
Country: China
ProdList: 50
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9442
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 021-50430803 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9352
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7876
Advantage: 55

Shanghai XIYU Chemical Technology Co.,Ltd.

Tel: 021-61052090 15221126179
Fax: 021-38473230
Country: China
ProdList: 368
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9908
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9636
Advantage: 58

Shanghai AQBioPharma Co., Ltd.

Tel: 13764862135
Fax: 51370935-8011
Email: yaoliang.ni@aqbiopharma.com.cn
Country: China
ProdList: 2715
Advantage: 58

Mashilabs (Shanghai) Co.,Ltd.

Tel: 021-00000000 19916721580
Fax: QQ：3154870176
Email: info@mashilabs.com
Country: China
ProdList: 4115
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12357
Advantage: 58

shanghai sinofluoro chemicals co., ltd.

Tel: 15800445152
Fax: 021-64278603
Email: sales@sinofluoro.com
Country: China
ProdList: 299
Advantage: 59

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Tongling HengYou Biotechnology Co., Ltd.

Tel: 021-50426030 13856289449
Fax: 021-50426030
Email: 2630597085@qq.com
Country: China
ProdList: 1889
Advantage: 55

Shenzhen Chim Biotech Co., Ltd.

Tel: 0755-36320761 13692196024
Fax: 0755-28364769
Email: sales@chimchem.com
Country: China
ProdList: 501
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 021-61984905-1 18016477331
Email: synchempharma@aliyun.com
Country: China
ProdList: 6454
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

Chengdu Yuanda chemical co.,ltd

Tel: 028-85356300 18980937689
Fax: +86-28-85356300
Email: chenquanxing@126.com
Country: China
ProdList: 100
Advantage: 55

BTC Pharmaceutical CO. Ltd

Tel: 0513-0513-68015-397-397 15716293042
Fax: 0513-68015394
Email: sales14@btcpharm.com
Country: China
ProdList: 652
Advantage: 55

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 5881
Advantage: 65

Central Glass Trading(Shanghai) Co., ltd.

Tel: 021-62199791 62199792
Fax: 021-6275269
Email: sales@cgco.com.cn
Country: China
ProdList: 33
Advantage: 55

Chengdu Xiaojia Technology Co., Ltd.

Tel: 15902830537
Email: 3644356552@qq.com
Country: China
ProdList: 1014
Advantage: 55

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-50664929, 13971561712
Fax: 027-50664927 / QQ: 3452835437
Email: hubxys2001@163.com
Country: China
ProdList: 1437
Advantage: 55

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9190
Advantage: 65

Less

View Lastest Price from 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate manufacturers

Hebei Duling International Trade Co. LTD

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $43.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 tons
Release date: 2023-03-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-TRANS-4-FLUORO-L-PROLINE 203866-14-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

203866-14-2, 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylateRelated Search:

Nr (2R,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid (2R,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid N-BOC-cis-4-fluoro-L-proline Cbz-D-Valine L-Proline D-Proline N-Boc-cis-4-Fluoro-D-Proline BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-Boc-trans-4-fluoro-L-proline methyl ester N-BOC-4,4-difluoro-L-proline BOC-TRANS-4-FLUORO-5-OXO-L-PROLINE METHYL ESTER 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID

N-BOC-TRANS-4-FLUORO-L-PROLINE

N-T-BOC-TRANS-4-FLUORO-L-PROLINE

N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE

BOC-TRANS-4-FLUORO-L-PROLINE

(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected

trans-4-Fluoro-L-proline, N-BOC protected

(2S,4R)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid

(2R,4S)-N-BOC-4-FLUORO-D-PROLINE

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid

(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid

N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline

(2S,4R)-4-FLUORO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(2R,4S)-N-Boc-trans-4-Fluoro-D-proline methyl ester

(2R,4S)-N-Boc-trans-4-Fluoro-D-proline

trans-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid

N-Boc-Tran-4-Fluoro-L-proline

Boc-trans-4-fluoro-Pro-OH

(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline N-Boc-trans-4-fluoro-L-proline

1-BOC-Trans-4-fluoro-L-proline

(2S,4R)-1-Boc-4-fluoropyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboyxlic acid

(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid

(2S,4R)-4-Fluoro-1,2-pyrrolidinedicarboxylic Acid tert-B utyl Ester

1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4R)-

(2S,4R)-N-Boc-4-fluoropyrrolidine-2-carboxy lic acid

(2S,4R)-1-(tert-Dutoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid

(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid &gt

(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylicaci

BOC-TRANS-4-FLUORO-L-PROLINE USP/EP/BP

TIANFU CHEM --BOC-TRANS-4-FLUORO-L-PROLINE

Boc-trans-4-F-Pro-OH

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

1-(tert-Butyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

203866-14-2

Carboxylic Acids (Chiral)

Chiral Building Blocks

Synthetic Organic Chemistry

Chiral Building Blocks

Heterocyclic Building Blocks

Pyrrolidines