1,1-Cyclobutanedicarboxylic acid

Uses

Product Name: 1,1-Cyclobutanedicarboxylic acid
CAS No.: 5445-51-2
Chemical Name: 1,1-Cyclobutanedicarboxylic acid
Synonyms: CYCLOBUTANE-1,1-DICARBOXYLIC ACID;1-Cyclobutanedicarboxylic acid;H2cbdca;226-651-2;1,1-Cyclobutanedicar;Carboplatin Impurity 1;Carboplatin impurity B;obutane-1,1-dicarboxyL;1,1-Dicarboxycyclobutane;Carboplatin EP Impurity B
CBNumber: CB2315559
Molecular Formula: C6H8O4
Formula Weight: 144.13
MOL File: 5445-51-2.mol

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1,1-Cyclobutanedicarboxylic acid Property

Melting point:: 158 °C(lit.)
Boiling point:: 222.71°C (rough estimate)
Density: 1.3217 (rough estimate)
refractive index: 1.5800 (estimate)
storage temp.: Store below +30°C.
solubility: DMSO (Slightly), Methanol (Slightly)
pka: pK1:3.13 ;pK2:5.88 (25°C)
form: Fine Crystalline Powder
color: White
BRN: 2046031
InChI: InChI=1S/C6H8O4/c7-4(8)6(5(9)10)2-1-3-6/h1-3H2,(H,7,8)(H,9,10)
InChIKey: CCQPAEQGAVNNIA-UHFFFAOYSA-N
SMILES: C1(C(O)=O)(C(O)=O)CCC1
CAS DataBase Reference: 5445-51-2(CAS DataBase Reference)
NIST Chemistry Reference: 1,1-Cyclobutanedicarboxylic acid(5445-51-2)
EPA Substance Registry System: 1,1-Cyclobutanedicarboxylic acid (5445-51-2)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45-28A
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
RTECS: GU1335000
Hazard Note: Corrosive
TSCA: T
HazardClass: 8
PackingGroup: III
HS Code: 29172000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C95803
Product name: Cyclobutane-1,1-dicarboxylic acid
Purity: 99%
Packaging: 5g
Price: $57.1
Updated: 2025/07/31

TCI Chemical

Product number: C0769
Product name: 1,1-Cyclobutanedicarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: C0769
Product name: 1,1-Cyclobutanedicarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $107
Updated: 2025/07/31

TRC

Product number: B416503
Product name: 1,1-Cyclobutanedicarboxylic Acid
Packaging: 100g
Price: $205
Updated: 2021/12/16

TRC

Product number: B416503
Product name: 1,1-Cyclobutanedicarboxylic Acid
Packaging: 25g
Price: $75
Updated: 2021/12/16

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1,1-Cyclobutanedicarboxylic acid Chemical Properties,Usage,Production

Uses

1,1-Cyclobutanedicarboxylic Acid(5445-51-2) is used in the design, studies and structural model of antitumor dicycloplatin a clinical cancer drug. Hydrolysis mechanism of second-generation anticancer drug carboplatin.

Chemical Properties

white fine crystalline powder

Definition

ChEBI: Cyclobutane-1,1-dicarboxylic acid is a cyclobutanedicarboxylic acid. It is a conjugate acid of a cyclobutane-1,1-dicarboxylate(1-).

Application

1,1-Cyclobutanedicarboxylic acid can be used as:
A reactant to synthesize lithium coordination polymer by treating with lithium carbonate.
A ligand to prepare various lanthanide metal-organic frameworks (LnMOFs) via a solvothermal method. Eu+3 based MOF is applicable as a selective chemical sensor for detecting CH3OH due to its high luminescence quantum yield.
It can also be used as a starting material in the synthesis of carboplatin (cis-diammine(1,1-cyclobutanedicarboxyl-ate)platinum(II)).

1,1-Cyclobutanedicarboxylic acid Preparation Products And Raw materials

Raw materials

Sodium ethoxide Sodium Methoxide Diethyl azodicarboxylate Bromine 1-Bromo-3-chloropropane

Preparation Products

ZENIPLATIN Cyclobutanecarboxylic acid Carboplatin ENLOPLATIN

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1,1-Cyclobutanedicarboxylic acid Suppliers

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View Lastest Price from 1,1-Cyclobutanedicarboxylic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1,1-Cyclobutanedicarboxylic acid 5445-51-2
Price: US $0.00/MG
Min. Order: 100MG
Purity: 98.0%
Supply Ability: 1kg/month
Release date: 2022-12-29

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,1-Cyclobutanedicarboxylic acid 5445-51-2
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 200TON
Release date: 2024-10-31

Moxin Chemicals

Product: Carboplatin EP Impurity B 5445-51-2
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 100000
Release date: 2025-03-12

5445-51-2, 1,1-Cyclobutanedicarboxylic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate CYCLOBUTANE Cyclohexanecarboxylic acid Cyclopropane Hyaluronic acid Phthalic acid n-Butane Dimethyl phthalate Potassium hydrogen phthalate 1-Chloro-2-methylpropane Methyl 4-tert-butylbenzoate ISOBUTANE 2,5-PYRIDINEDICARBOXYLIC ACID Isophthalic acid Folic acid Bis(2-ethylhexyl) phthalate OXALIC ACID Citric acid

Caboplatin IMpurity B (Cyclobutane-1,1-dicarboxylic acid)

1,1-Dicarboxylic acid cyclobutane

1,1-cyclobutanetwo forMic acid

1,1-Cyclobutanedicarboxylic acid, 99% 25GR

1,1-Cyclobutanedicarboxylic acid, 99% 5GR

1,1-Cyclobutanedicar

1-Cyclobutanedicarboxylic acid

Cyclobutane-1,1-dicarboxylic acid 99%

1,1-Dicarboxycyclobutane

1,1-Cyclobutanedicarboxylic acid,99%

Carboplatin Impurity 1

Carboplatin impurity B

226-651-2

CYCLOBUTANE-1,1-DICARBOXYLIC ACID

1,1-CYCLOBUTANEDICARBOXYLIC ACID

1,1-Cyclobutanedicarboxylic acid for synthesis

Cyclobutane-1,1-DicarboxylicAcid,>98%

1,1-cyclobutanedicarboxylic

Cyclobutane-1,1-dicarboxylic

1,1-Cyclobutanedicarboxylic acid 99%

Carboplatin Impurity B (Cyclobutane-1,1-dicarboxylic acid)

Carboplatin EP Impurity B

1,1-Cyclobutanedicarboxylic acid, 99%, for synthesis

1,1-Cyclobutanedicarboxylic Acid &gt

1,1-CYCLOBUTANEDICARBOXYLIC ACID FOR SYN

obutane-1,1-dicarboxyL

H2cbdca

1, 1-Cyclobutanedicarboxylic Acid CAS 5445-51-2

1,1-cyclobutanedicarboxylic 1，

1,1-Cyclobutanedicarboxylic acidQ: What is 1,1-Cyclobutanedicarboxylic acid Q: What is the CAS Number of 1,1-Cyclobutanedicarboxylic acid Q: What is the storage condition of 1,1-Cyclobutanedicarboxylic acid Q: What are the applications of 1,1-Cyclobutanedicarboxylic acid

TIANFUCHEM-- 5445-51-2-- 1,1-Cyclobutanedicarboxylic acid in stock

1,2,3-1H-Triazole 288-36-8

1,1-Cyclobutanedicarboxylic acid (7CI, 8CI, 9CI, ACI)

Carboplatin Intermediates

1，1-Cycbobutanedicarboxylicacid

5445-51-2

5445-52-2

Simple 4-Membered Ring Compounds

Cyclobutanes & Cyclobutenes

Carboxylic Acids

Carbonyl Compounds

Building Blocks

Organic Building Blocks

C6

pharmaceutical

Carboxylic Acids

Organic acids

Cyclobutanes & Cyclobutenes

Simple 4-Membered Ring Compounds

Carboxylic Acids

Ring Systems

Cycloalkanes

Carbonyl Compounds

bc0001

C6