Elastase

Product Name: Elastase
CAS No.: 9004-06-2
Chemical Name: Elastase
Synonyms: ELA2;ELANE;elaszym;ELASTASE;Eiastase;Elastase-2;e.c.3.4.4.7;Elastase ES;EC 3.4.21.37;EC 3.4.21.36
CBNumber: CB2398822
Formula Weight: 0
MOL File: Mol file

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Elastase Property

storage temp.: -20°C
form: lyophilized powder
CAS DataBase Reference: 9004-06-2
EPA Substance Registry System: Elastase (9004-06-2)

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Safety

Hazard Codes: B
WGK Germany: 3
F: 3-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB1305716
Product name: ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 400μl
Price: $481
Updated: 2024/03/01

Sigma-Aldrich

Product number: E8140
Product name: Elastase from human leukocytes
Purity: lyophilized powder, ≥50?units/mg protein (Bradford)
Packaging: 1unit
Price: $228
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324681
Product name: Elastase, Human Neutrophil
Purity: Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans
Packaging: 50μg
Price: $318
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324681
Product name: Elastase, Human Neutrophil
Purity: Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans
Packaging: 100μg
Price: $513
Updated: 2024/03/01

Usbiological

Product number: E2255-25
Product name: Elastase, Human Neutrophil
Packaging: 100ug
Price: $583
Updated: 2021/12/16

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Elastase Chemical Properties,Usage,Production

Uses

Elastase from human leukocytes has been used:

to measure serum elastase activity
in proteolytic digestion of fibronectin and salivary glands
in neutrophil elastase (NE) activity assay
cell-free NE digestion of E-cadherin
scratch wound assay
in a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal models

Elastase has been used to digest fibronectin. The results were compared with fibronectin digestion by crude human leukocyte homogenate to examine the presence of fibronectin peptides in saliva of patients with Sj?gren′s syndrome. It has also been used as a reference to determine the elastase activity in cell lysates. This study examined the effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells. These blast cells were from patients with acute promyelocytic leukemia.

General Description

Elastase is a proteolytic enzyme. It is a member of the subgroup named, peptidyl peptide hydrolases. It is a major anatomic constituent of arteries. It is mainly found in the pancreas and pancreatic juice of various birds and mammals. It is also present in human serum, granulocytes and erythrocytes.

Biochem/physiol Actions

Elastase enzyme is capable of releasing soluble peptides from insoluble elastin fibers with the help of a proteolytic process. It can stimulate disintegration of the axoneme with the help of adenosine triphosphate (ATP). Unlike pancreatic elastase the leukocyte enzyme has a preferential cleavage for the carboxyl side of valine, but will also cleave to a lesser extent after alanine. Natural substrates include elastin, cartilage proteoglycans, collagen types I, II, II and IV, and fibronectin.

Elastase Preparation Products And Raw materials

Raw materials

Separation resin Talc Adsorption resin Ammonium chloride

Preparation Products

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9004-06-2, ElastaseRelated Search:

ELASTASE SUBSTRATE VIII, COLORIMETRIC Elastase ELASTASE SUBSTRATE I, COLORIMETRIC PSEUDOLYSIN ELASTASE SUBSTRATE V, FLUOROGENIC,ELASTASE SUBSTRATE V ELASTASE SUBSTRATE II, COLORIMETRIC ELASTASE INHIBITOR III ELASTASE SUBSTRATE VII ELASTASE INHIBITOR,ELASTASE INHIBITOR I ELASTASE INHIBITOR II ELASTASE SUBSTRATE VI ELASTASE SUBSTRATE IV, COLORIMETRIC NEUTROPHIL ELASTASE (AB-1) MONOCLONAL ANTIBODY,ANTI-ELASTASE, CYT,ANTI-ELASTASE, HUMAN MACROPHAGE ELASTASE (HUMAN FIBROBLASTS) Elastase ELASTASE, NEUTROPHIL MONOCLONAL ANTIBODY 100 μG ELASTASE FROM HUMAN NEUTRO-PHILS CA. 18 U/MG PROTEIN LYOPHIL. SUBSTRATE AAPV ELASTASE

neutrophil elastase

PANCREATOPEPTIDASE E

LYSOSOMAL ELASTASE

macrophage metalloelastase

EC 3.4.21.36

EC 3.4.21.37

ELASTASE

ELASTASE, LEUKOCYTE

ELASTASE, NEUTROPHIL, HUMAN

ELASTASE, HUMAN NEUTROPHIL

ELASTASE, HUMAN NEUTROPHILS

elaszym

LEUKOCYTE ELASTASE, HUMAN NEUTROPHILS

e.c.3.4.4.7

elastolytic enzyme

pancre-atopeptidase

elastase from human leukocytes

Eiastase

ELASTASE, LEUKOCYTE FROM HUMAN*LEUKOCYTE S

ELASTASE 2X-CRYSTALLIZED

ELASTASE FROM PORCINE PANCREAS LYOPHILIZED POWDER

ELASTASE FROM HUMAN NEUTROPHILS (WHITE LEUCOCYTES)ACTIVITY: 18-30 UNITS/MG PROTEIN SALT-FREE, LYOPHILIZED SOLID 98% BY SDS-PAGE

Elastase ES

3-(4-hydroxy-2,3-dimethoxy-phenyl)-3,4-dihydro-2H-chromen-7-ol

3-(4-hydroxy-2,3-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-ol

3-(4-hydroxy-2,3-dimethoxy-phenyl)chroman-7-ol

Elastase from human neutrophils min. 10 U/mg

ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit

Bone marrow serine protease

ELA2

ELANE

Elastase-2

Elastasefromhumanneutrophils(whiteleucocytes),activity:18-30u/mgproteinsalt-free,lyophilizedsolid

fromporcinepancreaslyophilizedpowder

Elastase from porcine pancreas, lyophil.

Elastase froM huMan neutrophils Min. 10 U/Mg lyophil.

Elastase， human leucocytes

9004-06-2

9004-02-6

9004-6-2

Enzymes, Inhibitors, and Substrates

BioChemical

Biochemicals and Reagents

Proteolytic Enzymes and Substrates

Proteolytic Enzymes