Elastase
- Product Name
- Elastase
- CAS No.
- 9004-06-2
- Chemical Name
- Elastase
- Synonyms
- ELA2;ELANE;elaszym;ELASTASE;Eiastase;Elastase-2;e.c.3.4.4.7;Elastase ES;EC 3.4.21.37;EC 3.4.21.36
- CBNumber
- CB2398822
- Formula Weight
- 0
- MOL File
- Mol file
Elastase Property
- storage temp.
- -20°C
- form
- lyophilized powder
- color
- White to off-white
- CAS DataBase Reference
- 9004-06-2
- EPA Substance Registry System
- Elastase (9004-06-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SAB1305716
- Product name
- ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 400μl
- Price
- $481
- Updated
- 2024/03/01
- Product number
- E8140
- Product name
- Elastase from human leukocytes
- Purity
- lyophilized powder, ≥50?units/mg protein (Bradford)
- Packaging
- 1unit
- Price
- $228
- Updated
- 2024/03/01
- Product number
- 324681
- Product name
- Elastase, Human Neutrophil
- Purity
- Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans
- Packaging
- 50μg
- Price
- $318
- Updated
- 2024/03/01
- Product number
- 324681
- Product name
- Elastase, Human Neutrophil
- Purity
- Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans
- Packaging
- 100μg
- Price
- $513
- Updated
- 2024/03/01
- Product number
- E2255-25
- Product name
- Elastase, Human Neutrophil
- Packaging
- 100ug
- Price
- $583
- Updated
- 2021/12/16
Elastase Chemical Properties,Usage,Production
Uses
Elastase from human leukocytes has been used:
- to measure serum elastase activity
- in proteolytic digestion of fibronectin and salivary glands
- in neutrophil elastase (NE) activity assay
- cell-free NE digestion of E-cadherin
- scratch wound assay
- in a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal models
General Description
Elastase is a proteolytic enzyme. It is a member of the subgroup named, peptidyl peptide hydrolases. It is a major anatomic constituent of arteries. It is mainly found in the pancreas and pancreatic juice of various birds and mammals. It is also present in human serum, granulocytes and erythrocytes.
Biochem/physiol Actions
Elastase enzyme is capable of releasing soluble peptides from insoluble elastin fibers with the help of a proteolytic process. It can stimulate disintegration of the axoneme with the help of adenosine triphosphate (ATP). Unlike pancreatic elastase the leukocyte enzyme has a preferential cleavage for the carboxyl side of valine, but will also cleave to a lesser extent after alanine. Natural substrates include elastin, cartilage proteoglycans, collagen types I, II, II and IV, and fibronectin.