ChemicalBook > CAS DataBase List > Difluoroacetic acid
Difluoroacetic acid
- Product Name
- Difluoroacetic acid
- CAS No.
- 381-73-7
- Chemical Name
- Difluoroacetic acid
- Synonyms
- 2,2-DIFLUOROACETIC ACID;DIFLUOROACETATE;ifluoroaceticaci;difluoro-aceticaci;VITAS-BB TBB000649;DIFLUOROACETIC ACID;Difluoroaceticacid98%;Acetic acid, difluoro-;1,1-DIFLUOROACETIC ACID;Twotrifluoroacetic acid
- CBNumber
- CB2700577
- Molecular Formula
- C2H2F2O2
- Formula Weight
- 96.03
- MOL File
- 381-73-7.mol
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Difluoroacetic acid Property
- Melting point:
- -1 °C (lit.)
- Boiling point:
- 132-134 °C (lit.)
- Density
- 1.526 g/mL at 25 °C (lit.)
- vapor pressure
- 11.7hPa at 25℃
- refractive index
- n20/D 1.344(lit.)
- Flash point:
- 174 °F
- storage temp.
- 2-8°C
- solubility
- 540.54g/L in organic solvents at 20 ℃
- form
- Liquid
- pka
- pK1:1.33 (25°C)
- color
- Clear colorless to light brown
- Specific Gravity
- 1.527 (20℃)
- Water Solubility
- 1000g/L at 37℃
- BRN
- 1098588
- InChIKey
- PBWZKZYHONABLN-UHFFFAOYSA-N
- LogP
- 0.601 at 37℃
- CAS DataBase Reference
- 381-73-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Difluoroacetic acid(381-73-7)
- EPA Substance Registry System
- Acetic acid, difluoro- (381-73-7)
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Safety
- Hazard Codes
- C
- Risk Statements
- 34-35
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- RTECS
- AG9900000
- Hazard Note
- Corrosive
- TSCA
- T
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29159080
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 142859
- Product name
- Difluoroacetic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $78.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 142859
- Product name
- Difluoroacetic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $191
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 00922
- Product name
- Difluoroacetic acid
- Purity
- for LC-MS LiChropur?, ≥97.5% (GC)
- Packaging
- 10X1ML
- Price
- $252
- Updated
- 2022/05/15
Sigma-Aldrich
- Product number
- 00922
- Product name
- Difluoroacetic acid
- Purity
- for LC-MS LiChropur?, ≥97.5% (GC)
- Packaging
- 50ML
- Price
- $802
- Updated
- 2022/05/15
TCI Chemical
- Product number
- D1423
- Product name
- Difluoroacetic Acid
- Purity
- >97.0%(T)
- Packaging
- 5g
- Price
- $50
- Updated
- 2024/03/01
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Difluoroacetic acid Chemical Properties,Usage,Production
Chemical Properties
clear colorless to light brown liquid
Uses
Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.
Definition
ChEBI: A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by fluorines.
Flammability and Explosibility
Non flammable
Purification Methods
Purify the acid by distilling over P2O5. The acid chloride is a fuming liquid b 25o/atm, and the amide has b 108.6o/35mm, m 52o (from *C6H6), and the anilide has b 90o/1mm, 114o/5mm, m 58o [Henne & Pelley J Am Chem Soc 74 1426 1952, Coffman et al. J Org Chem 14 749 1949, NMR: Meyer et al. J Am Chem Soc 75 4567 1953, pK: Wegscheider Z Phys Chem 69 614 1909]. [Beilstein 2 IV 455.]
Difluoroacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Difluoroacetic acid manufacturers
Hebei Guanlang Biotechnology Co., Ltd.
- Product
- Difluoroacetic acid 381-73-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-03-07
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- Difluoroacetic acid 381-73-7
- Price
- US $90.00-900.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-08
Hefei TNJ Chemical Industry Co.,Ltd.
- Product
- Difluoroacetic Acid 381-73-7
- Price
- US $0.00/L
- Min. Order
- 200L
- Purity
- 99%
- Supply Ability
- 1000MT
- Release date
- 2019-03-08
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