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Difluoroacetic acid

Product Name
Difluoroacetic acid
CAS No.
381-73-7
Chemical Name
Difluoroacetic acid
Synonyms
2,2-DIFLUOROACETIC ACID;DIFLUOROACETATE;ifluoroaceticaci;difluoro-aceticaci;VITAS-BB TBB000649;DIFLUOROACETIC ACID;Difluoroaceticacid98%;Acetic acid, difluoro-;1,1-DIFLUOROACETIC ACID;Twotrifluoroacetic acid
CBNumber
CB2700577
Molecular Formula
C2H2F2O2
Formula Weight
96.03
MOL File
381-73-7.mol
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Difluoroacetic acid Property

Melting point:
-1 °C (lit.)
Boiling point:
132-134 °C (lit.)
Density 
1.526 g/mL at 25 °C (lit.)
vapor pressure 
11.7hPa at 25℃
refractive index 
n20/D 1.344(lit.)
Flash point:
174 °F
storage temp. 
2-8°C
solubility 
540.54g/L in organic solvents at 20 ℃
form 
Liquid
pka
pK1:1.33 (25°C)
color 
Clear colorless to light brown
Specific Gravity
1.527 (20℃)
Water Solubility 
1000g/L at 37℃
BRN 
1098588
InChIKey
PBWZKZYHONABLN-UHFFFAOYSA-N
LogP
0.601 at 37℃
CAS DataBase Reference
381-73-7(CAS DataBase Reference)
NIST Chemistry Reference
Difluoroacetic acid(381-73-7)
EPA Substance Registry System
Acetic acid, difluoro- (381-73-7)
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Safety

Hazard Codes 
C
Risk Statements 
34-35
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
AG9900000
Hazard Note 
Corrosive
TSCA 
T
HazardClass 
8
PackingGroup 
II
HS Code 
29159080
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H332Harmful if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
142859
Product name
Difluoroacetic acid
Purity
98%
Packaging
5g
Price
$78.8
Updated
2024/03/01
Sigma-Aldrich
Product number
142859
Product name
Difluoroacetic acid
Purity
98%
Packaging
25g
Price
$191
Updated
2024/03/01
Sigma-Aldrich
Product number
00922
Product name
Difluoroacetic acid
Purity
for LC-MS LiChropur?, ≥97.5% (GC)
Packaging
10X1ML
Price
$252
Updated
2022/05/15
Sigma-Aldrich
Product number
00922
Product name
Difluoroacetic acid
Purity
for LC-MS LiChropur?, ≥97.5% (GC)
Packaging
50ML
Price
$802
Updated
2022/05/15
TCI Chemical
Product number
D1423
Product name
Difluoroacetic Acid
Purity
>97.0%(T)
Packaging
5g
Price
$50
Updated
2024/03/01
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Difluoroacetic acid Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light brown liquid

Uses

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by fluorines.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the acid by distilling over P2O5. The acid chloride is a fuming liquid b 25o/atm, and the amide has b 108.6o/35mm, m 52o (from *C6H6), and the anilide has b 90o/1mm, 114o/5mm, m 58o [Henne & Pelley J Am Chem Soc 74 1426 1952, Coffman et al. J Org Chem 14 749 1949, NMR: Meyer et al. J Am Chem Soc 75 4567 1953, pK: Wegscheider Z Phys Chem 69 614 1909]. [Beilstein 2 IV 455.]

Difluoroacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Difluoroacetic acid Suppliers

Shandong Carbon Spring New Materials Co., Ltd.
Tel
13658618215
Email
308410472@qq.com
Country
China
ProdList
55
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
0513-0513-68015397 18862996710
Fax
0513-68015394
Email
sales12@btcpharm.com
Country
China
ProdList
689
Advantage
55
SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
373
Advantage
60
Qingdao Dexin Chemical Co. LTD
Tel
18560810705
Email
354907727@qq.com
Country
China
ProdList
161
Advantage
58
West fluorine technology co., ltd
Tel
0531-85906692; 15588812394
Fax
86-0531-85906692
Email
325912682@qq.com
Country
China
ProdList
370
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
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View Lastest Price from Difluoroacetic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Difluoroacetic acid 381-73-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-22
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Difluoroacetic acid 381-73-7
Price
US $90.00-900.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08
Hefei TNJ Chemical Industry Co.,Ltd.
Product
Difluoroacetic Acid 381-73-7
Price
US $0.00/L
Min. Order
200L
Purity
99%
Supply Ability
1000MT
Release date
2019-03-08

381-73-7, Difluoroacetic acidRelated Search:


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