ChemicalBook > CAS DataBase List > D-Proline

D-Proline

Product Name
D-Proline
CAS No.
344-25-2
Chemical Name
D-Proline
Synonyms
Proline;H-D-PRO-OH;D-PRO;D-Pro-OH;(R)-PYRROLIDINE-2-CARBOXYLIC ACID;(2R)-Pyrrolidine-2-carboxylic acid;D-PYRROLIDINE-2-CARBOXYLIC ACID;D-PyrroL;D-PROLINE;D(+)-PROLINE
CBNumber
CB2754303
Molecular Formula
C5H9NO2
Formula Weight
115.13
MOL File
344-25-2.mol
More
Less

D-Proline Property

Melting point:
223 °C (dec.) (lit.)
alpha 
84.75 º (c=4, H2O)
Boiling point:
215.41°C (rough estimate)
Density 
1.36
refractive index 
85 ° (C=4, H2O)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Methanol (Slightly), Water (Sparingly)
form 
Powder
pka
1.952(at 25℃)
color 
White to yellow to pale brown
optical activity
[α]22/D +85.0°, c = 4 in H2O
Water Solubility 
soluble >1000 g/L (20 ºC)
Sensitive 
Hygroscopic
BRN 
80811
InChIKey
ONIBWKKTOPOVIA-SCSAIBSYSA-N
LogP
-0.060 (est)
CAS DataBase Reference
344-25-2(CAS DataBase Reference)
EPA Substance Registry System
D-Proline (344-25-2)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
22-24/25-36/37/39-26
WGK Germany 
3
3-10
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
858919
Product name
D-Proline
Purity
ReagentPlus , ≥99%
Packaging
500mg
Price
$46.7
Updated
2024/03/01
Sigma-Aldrich
Product number
858919
Product name
D-Proline
Purity
ReagentPlus , ≥99%
Packaging
5g
Price
$114
Updated
2024/03/01
TCI Chemical
Product number
P0994
Product name
D-Proline
Purity
>98.0%(T)
Packaging
5g
Price
$76
Updated
2024/03/01
TCI Chemical
Product number
P0994
Product name
D-Proline
Purity
>98.0%(T)
Packaging
25g
Price
$242
Updated
2024/03/01
Alfa Aesar
Product number
A10682
Product name
D-Proline, 99%
Packaging
1g
Price
$42.65
Updated
2024/03/01
More
Less

D-Proline Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Occurrence

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.

Uses

Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.

Uses

Labelled D-Proline Lasubine II and (+)-Cermizine C.

Uses

proline is a skin-conditioning agent. An amino acid found in the collagen molecule.

Definition

ChEBI: D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4

D-Proline Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

D-Proline Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Wuxi Bikang Bioengineering Co., Ltd
Tel
0510-80245888 400-0510-518
Fax
0510-80245999
Email
1258079079@qq.com
Country
China
ProdList
46
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Shangqiu Ladybug Network Technology Co., LTD
Tel
0370-2070160 17550096163
Fax
18736733639
Email
2986449836@qq.com
Country
China
ProdList
3032
Advantage
58
Huzhou Chenxi Environmental Protection Technology Co., Ltd.
Tel
0572-0572-16762203950 16762203950
Email
3775386035@qq.com
Country
China
ProdList
70
Advantage
58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82371986 15064117275
Fax
0531-82375893
Email
daisy@jndxj.com
Country
China
ProdList
1321
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
More
Less

View Lastest Price from D-Proline manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
D-Proline 344-25-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-06
Hubei Lidu New Material Technology Co., Ltd
Product
D-Proline 344-25-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20t
Release date
2024-12-11
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D-Proline 344-25-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98.5%-101%
Supply Ability
500kg
Release date
2021-06-02

344-25-2, D-ProlineRelated Search:


  • D-Pro-OH
  • D-Proline≥ 99% (Assay)
  • D-Proline,99%e.e.
  • (R)-(+)-PROLINE
  • (R)-PYRROLIDINE-2-CARBOXYLIC ACID
  • D-2-PYRROLIDINECARBOXYLIC ACID
  • D-PYRROLIDINE-2-CARBOXYLIC ACID
  • D(+)-PROLINE
  • D-PROLINE
  • D-PRO
  • H-D-PYRD(2)-OH
  • H-D-PRO-OH
  • D-Proline,99%
  • H-D-PRO-OH UPS24 (IN BULK QUANTITY)
  • D-(+)-Prolin
  • Proline
  • Glycinate Fumasuan Salt
  • (2R)-Pyrrolidine-2-carboxylic acid
  • D-PROLINE, 99+% (98% EE/GLC)
  • D-PyrroL
  • idine-2-carboxyL
  • Captopril Impurity 32
  • D-(+)-PROLINE ((R)-(+)-PROLINE)
  • D-PROLINE extrapure
  • D-Proline-d3
  • D-Proline, (2R)-2-Carboxypyrrolidine
  • D-Proline ReagentPlus(R), >=99%
  • D-Proline Vetec(TM) reagent grade, 98%
  • D-Proline&gt
  • D-Proline,98%
  • D-Proline USP/EP/BP
  • dextro-(+)-proline
  • D-Proline CAS No. 344-25-2
  • D-Proline extrapure CHR, 99%
  • D-Proline (9CI, ACI)
  • Captopril Impurity 38
  • (2R)-pyrrolidin-1-ium-2-carboxylate
  • 344-25-2
  • 24344-25-2
  • 145-85-3
  • 344-25-5
  • C5H9NO2
  • CARBOXYLIC ACID
  • Amino Acid Derivatives
  • Proline
  • Peptide Synthesis
  • Specialty Synthesis
  • Amino Acids and Derivatives
  • Proline [Pro, P]
  • Amino Acids and Derivatives
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • Amino Acids & Derivatives
  • Heterocycles
  • Isotope Labelled Compounds
  • 206-452-7
  • Amino ACIDS SERIES