D-Proline
- Product Name
- D-Proline
- CAS No.
- 344-25-2
- Chemical Name
- D-Proline
- Synonyms
- Proline;H-D-PRO-OH;D-PRO;D-Pro-OH;(R)-PYRROLIDINE-2-CARBOXYLIC ACID;(2R)-Pyrrolidine-2-carboxylic acid;D-PYRROLIDINE-2-CARBOXYLIC ACID;D-PyrroL;D-PROLINE;D(+)-PROLINE
- CBNumber
- CB2754303
- Molecular Formula
- C5H9NO2
- Formula Weight
- 115.13
- MOL File
- 344-25-2.mol
D-Proline Property
- Melting point:
- 223 °C (dec.) (lit.)
- alpha
- 84.75 º (c=4, H2O)
- Boiling point:
- 215.41°C (rough estimate)
- Density
- 1.36
- refractive index
- 85 ° (C=4, H2O)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Methanol (Slightly), Water (Sparingly)
- pka
- 1.952(at 25℃)
- form
- Powder
- color
- White to yellow to pale brown
- optical activity
- [α]22/D +85.0°, c = 4 in H2O
- Water Solubility
- soluble >1000 g/L (20 ºC)
- Sensitive
- Hygroscopic
- BRN
- 80811
- InChIKey
- ONIBWKKTOPOVIA-SCSAIBSYSA-N
- LogP
- -0.060 (est)
- CAS DataBase Reference
- 344-25-2(CAS DataBase Reference)
- EPA Substance Registry System
- D-Proline (344-25-2)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-24/25-36/37/39-26
- WGK Germany
- 3
- F
- 3-10
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29339990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 858919
- Product name
- D-Proline
- Purity
- ReagentPlus , ≥99%
- Packaging
- 500mg
- Price
- $46.7
- Updated
- 2024/03/01
- Product number
- 858919
- Product name
- D-Proline
- Purity
- ReagentPlus , ≥99%
- Packaging
- 5g
- Price
- $114
- Updated
- 2024/03/01
- Product number
- P0994
- Product name
- D-Proline
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $76
- Updated
- 2024/03/01
- Product number
- P0994
- Product name
- D-Proline
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $242
- Updated
- 2024/03/01
- Product number
- A10682
- Product name
- D-Proline, 99%
- Packaging
- 1g
- Price
- $42.65
- Updated
- 2024/03/01
D-Proline Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Occurrence
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.
Uses
Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.
Uses
Labelled D-Proline Lasubine II and (+)-Cermizine C.
Uses
proline is a skin-conditioning agent. An amino acid found in the collagen molecule.
Definition
ChEBI: D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4
D-Proline Preparation Products And Raw materials
Raw materials
Preparation Products
D-Proline Suppliers
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View Lastest Price from D-Proline manufacturers
- Product
- D-Proline 344-25-2
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-27
- Product
- D-Proline 344-25-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 99
- Supply Ability
- 20tons
- Release date
- 2024-02-06
- Product
- D-Proline 344-25-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98.5%-101%
- Supply Ability
- 500kg
- Release date
- 2021-06-02