D-Proline

Product Name: D-Proline
CAS No.: 344-25-2
Chemical Name: D-Proline
Synonyms: Proline;H-D-PRO-OH;D-PRO;D-Pro-OH;(R)-PYRROLIDINE-2-CARBOXYLIC ACID;(2R)-Pyrrolidine-2-carboxylic acid;D-PYRROLIDINE-2-CARBOXYLIC ACID;D-PyrroL;D-PROLINE;D(+)-PROLINE
CBNumber: CB2754303
Molecular Formula: C5H9NO2
Formula Weight: 115.13
MOL File: 344-25-2.mol

More

Less

D-Proline Property

Melting point:: 223 °C (dec.) (lit.)
alpha: 84.75 º (c=4, H2O)
Boiling point:: 215.41°C (rough estimate)
Density: 1.36
refractive index: 85 ° (C=4, H2O)
storage temp.: Inert atmosphere,Room Temperature
solubility: Methanol (Slightly), Water (Sparingly)
pka: 1.952(at 25℃)
form: Powder
color: White to yellow to pale brown
optical activity: [α]22/D +85.0°, c = 4 in H2O
Water Solubility: soluble >1000 g/L (20 ºC)
Sensitive: Hygroscopic
BRN: 80811
InChIKey: ONIBWKKTOPOVIA-SCSAIBSYSA-N
LogP: -0.060 (est)
CAS DataBase Reference: 344-25-2(CAS DataBase Reference)
EPA Substance Registry System: D-Proline (344-25-2)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 22-24/25-36/37/39-26
WGK Germany: 3
F: 3-10
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 858919
Product name: D-Proline
Purity: ReagentPlus , ≥99%
Packaging: 500mg
Price: $46.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 858919
Product name: D-Proline
Purity: ReagentPlus , ≥99%
Packaging: 5g
Price: $114
Updated: 2024/03/01

TCI Chemical

Product number: P0994
Product name: D-Proline
Purity: >98.0%(T)
Packaging: 5g
Price: $76
Updated: 2024/03/01

TCI Chemical

Product number: P0994
Product name: D-Proline
Purity: >98.0%(T)
Packaging: 25g
Price: $242
Updated: 2024/03/01

Alfa Aesar

Product number: A10682
Product name: D-Proline, 99%
Packaging: 1g
Price: $42.65
Updated: 2024/03/01

More

Less

D-Proline Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Occurrence

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.

Uses

Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.

Uses

Labelled D-Proline Lasubine II and (+)-Cermizine C.

Uses

proline is a skin-conditioning agent. An amino acid found in the collagen molecule.

Definition

ChEBI: D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4

D-Proline Preparation Products And Raw materials

Raw materials

L-Proline

Preparation Products

N-Boc-D-proline (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

More

Less

D-Proline Suppliers

Americas 1 Austria 1 Belgium 4 Canada 5 China 514 Europe 4 France 3 Germany 13 India 36 Japan 14 Poland 1 Slovakia 1 South Korea 2 Switzerland 9 United Kingdom 21 United States 74 USA 1 Global 704

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9685
Advantage: 58

More

Less

View Lastest Price from D-Proline manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: D-Proline 344-25-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-15

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: D-Proline 344-25-2
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99
Supply Ability: 20tons
Release date: 2024-02-06

Henan Fengda Chemical Co., Ltd

Product: D-Proline 344-25-2
Price: US $32.00-1.10/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-22

344-25-2, D-ProlineRelated Search:

D-Tartaric acid D-Alanine D-Proline trans-4-Hydroxy-D-proline N-Benzyloxycarbonyl-D-proline cis-4-Hydroxy-D-proline Fmoc-D-proline BOC-D-PRO-OSU AC-D-PRO-OH (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid Z-D-PYR-OH Methyl pyrrolidine-2-carboxylate hydrochloride D-Pyroglutamic acid Ethyl D-(-)-pyroglutamate Oxaceprol trans-4-Cyclohexyl-L-proline 1-(4-HYDROXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID,1-(4-HYDROXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID H-D-PRO-OTBU

D-Pro-OH

D-Proline≥ 99% (Assay)

D-Proline,99%e.e.

(R)-(+)-PROLINE

(R)-PYRROLIDINE-2-CARBOXYLIC ACID

D-2-PYRROLIDINECARBOXYLIC ACID

D-PYRROLIDINE-2-CARBOXYLIC ACID

D(+)-PROLINE

D-PROLINE

D-PRO

H-D-PYRD(2)-OH

H-D-PRO-OH

D-Proline,99%

H-D-PRO-OH UPS24 (IN BULK QUANTITY)

D-(+)-Prolin

Proline

Glycinate Fumasuan Salt

(2R)-Pyrrolidine-2-carboxylic acid

D-PROLINE, 99+% (98% EE/GLC)

D-PyrroL

idine-2-carboxyL

Captopril Impurity 32

D-(+)-PROLINE ((R)-(+)-PROLINE)

D-PROLINE extrapure

D-Proline-d3

D-Proline, (2R)-2-Carboxypyrrolidine

D-Proline ReagentPlus(R), >=99%

D-Proline Vetec(TM) reagent grade, 98%

D-Proline&gt

D-Proline，98%

D-Proline USP/EP/BP

dextro-(+)-proline

D-Proline CAS No. 344-25-2

D-Proline extrapure CHR, 99%

D-Proline (9CI, ACI)

Captopril Impurity 38

344-25-2

24344-25-2

145-85-3

344-25-5

C5H9NO2

CARBOXYLIC ACID

Amino Acid Derivatives

Proline

Peptide Synthesis

Specialty Synthesis

Amino Acids and Derivatives

Proline [Pro, P]

Amino Acids and Derivatives

alpha-Amino Acids

Amino Acids

Biochemistry

Amino Acids & Derivatives

Heterocycles

Isotope Labelled Compounds

206-452-7

Amino ACIDS SERIES

Miscellaneous Biochemicals