ChemicalBook > CAS DataBase List > ZK 756326

ZK 756326

Product Name
ZK 756326
CAS No.
874911-96-3
Chemical Name
ZK 756326
Synonyms
CS-2219;ZK 756326;ZK756326 2HCl;2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol;2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol;2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol;Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]-;2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride;2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride
CBNumber
CB2785596
Molecular Formula
C21H28N2O3
Formula Weight
356.46
MOL File
874911-96-3.mol
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ZK 756326 Property

storage temp. 
Desiccate at RT
form 
White solid.
Water Solubility 
Soluble to 100 mM in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
2565
Product name
ZK756326
Purity
≥99%(HPLC)
Packaging
10
Price
$170
Updated
2021/12/16
Tocris
Product number
2565
Product name
ZK756326
Purity
≥99%(HPLC)
Packaging
50
Price
$710
Updated
2021/12/16
Usbiological
Product number
257171
Product name
ZK 756326
Packaging
10mg
Price
$438
Updated
2021/12/16
TRC
Product number
P301395
Product name
2-​[2-​[4-​[(3-​Phenoxyphenyl)​methyl]​-​1-​piperazinyl]​ethoxy]​-ethanol
Packaging
0.5mg
Price
$45
Updated
2021/12/16
ApexBio Technology
Product number
B7109
Product name
ZK756326
Packaging
5mg
Price
$125
Updated
2021/12/16
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ZK 756326 Chemical Properties,Usage,Production

Uses

2-?[2-?[4-?[(3-?Phenoxyphenyl)?methyl]?-?1-?piperazinyl]?ethoxy]?-ethanol is a nonpeptide CCR8 chemokine receptor agonist that inhibits the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM (1). It is a useful compound to investigate the physiological role of CCR8 in HIV infection.

Biological Activity

Selective, non-peptide CCR8 chemokine receptor agonist (IC 50 values are 1.8 and 2.6 μ M for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α 2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

ZK 756326 Preparation Products And Raw materials

Raw materials

Preparation Products

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ZK 756326 Suppliers

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874911-96-3, ZK 756326Related Search:

(+)-ZK 216348 ZK824859 ZK824859 ZK 158252 ZK164015 ZK756326(dihydrochloride) ZK 93426 hydrochloride ZK 159222 ZK118182 isopropyl ester ZK-90055 (hydrochloride) ZK 110841 ZK 112993 FUDAEUIGIJZUAY-UMIRZPQISA-N ZK-261991 ZK 756326 1-[2(2-Hydroxyethoxy)ethyl]piperazine dihydrochloride

  • ZK 756326
  • 2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride
  • 2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol
  • ZK756326 2HCl
  • 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride
  • CS-2219
  • 2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol
  • Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]-
  • 2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol
  • 874911-96-3
  • C21H28N2O32HCl