DBCO-PEG2-NH-Boc

Product Name: DBCO-PEG2-NH-Boc
CAS No.: 2377004-08-3
Chemical Name: DBCO-PEG2-NH-Boc
Synonyms: DBCO-PEG2-NH-Boc;DBCO-PEG2-t-Bu Amine
CBNumber: CB28054698
Molecular Formula: C30H37N3O6
Formula Weight: 535.63
MOL File: 2377004-08-3.mol

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DBCO-PEG2-NH-Boc Property

Boiling point:: 802.8±65.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 12.23±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24382
Product name: DBCO-PEG2-NH-Boc
Purity: 98%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-24382
Product name: DBCO-PEG2-NH-Boc
Purity: 98%
Packaging: 100mg
Price: $460
Updated: 2021/12/16

BroadPharm

Product number: BP-24382
Product name: DBCO-PEG2-NH-Boc
Purity: 98%
Packaging: 250mg
Price: $850
Updated: 2021/12/16

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DBCO-PEG2-NH-Boc Chemical Properties,Usage,Production

Description

DBCO-PEG2-NH-Boc is a PEG linker with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions to further react.

Uses

DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG2-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG2-NH-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG2-NH-Boc Suppliers

China 20 United States 4 Global 24

Xi'an Confluore Biological Technology Co., Ltd.

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Alfa Chemistry

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Zhengzhou Convergence Chemical Co. LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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Shanghai Huici Pharmaceutical Technology Co., LTD

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Affinity（Wuhan）Ltd.

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2377004-08-3, DBCO-PEG2-NH-BocRelated Search:

DBCO-PEG1-amine 5,8,11,14,17,20-Hexaoxa-2,23-diazaheptacosanoic acid, 27-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-24,27-dioxo-, 1,1-dimethylethyl ester DBCO-PEG3-CH2CO-NHS DBCO-PEG4-amine DBCO-PEG4-SE DBCO-NHS Ester Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester DBCO-PEG4-DBCO DBCO-(CH2)2-NH2-CO-(CH2)3COOH-NHS DBCO-PEG3-acid Azadibenzocyclooctyne-Biotin conjugate 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(11,12-dihydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 2,3,5,6-tetrafluorophenyl ester DBCO-NH-(CH2)4COOH DBCO-PEG3-amine DBCO-NH-Boc

DBCO-PEG2-NH-Boc

DBCO-PEG2-t-Bu Amine

2377004-08-3