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DBCO-NH-(CH2)4COOH

Product Name
DBCO-NH-(CH2)4COOH
CAS No.
2375193-74-9
Chemical Name
DBCO-NH-(CH2)4COOH
Synonyms
DBCO-NH-(CH2)4COOH
CBNumber
CB78054693
Molecular Formula
C24H24N2O4
Formula Weight
404.46
MOL File
2375193-74-9.mol
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DBCO-NH-(CH2)4COOH Property

Boiling point:
770.9±60.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
pka
4.70±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg
Product number
288304
Product name
DBCO-NH-(CH2)4COOH
Purity
min.95%
Packaging
100mg
Price
$350
Updated
2021/12/16
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DBCO-NH-(CH2)4COOH Chemical Properties,Usage,Production

Uses

DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NH-(CH2)4COOH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-NH-(CH2)4COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-NH-(CH2)4COOH Suppliers

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