ChemicalBook > CAS DataBase List > 4-(4-Aminophenoxy)-N-methylpicolinamide

4-(4-Aminophenoxy)-N-methylpicolinamide

Product Name
4-(4-Aminophenoxy)-N-methylpicolinamide
CAS No.
284462-37-9
Chemical Name
4-(4-Aminophenoxy)-N-methylpicolinamide
Synonyms
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide;4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide;SL-M2;Sorafen;Sorafenib INT2;Sorafenib impurity A;Sorafenib Intermediate;Sorafenib tosylate INT III;Sorafenib Related Compound 23;[4-(4-Aminophenoxy-2-pyridyl)]
CBNumber
CB31175425
Molecular Formula
C13H13N3O2
Formula Weight
243.26
MOL File
284462-37-9.mol
More
Less

4-(4-Aminophenoxy)-N-methylpicolinamide Property

Melting point:
110-112°C
Boiling point:
476.8±40.0 °C(Predicted)
Density 
1.241±0.06 g/cm3(Predicted)
vapor pressure 
0.001-0.05Pa at 20-109.84℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
13.96±0.46(Predicted)
color 
White to Light yellow to Light orange
LogP
0.9 at 25℃ and pH7
Surface tension
71.71mN/m at 883.8mg/L and 20.1℃
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A2617
Product name
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
A2617
Product name
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$91
Updated
2024/03/01
TRC
Product number
A618940
Product name
[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide
Packaging
500mg
Price
$120
Updated
2021/12/16
TRC
Product number
A618940
Product name
[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide
Packaging
1g
Price
$165
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-1-9D
Product name
4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide
Packaging
500mg
Price
$298
Updated
2021/12/16
More
Less

4-(4-Aminophenoxy)-N-methylpicolinamide Chemical Properties,Usage,Production

Chemical Properties

Light-Brown Solid

Uses

Sorafenib intermediate

Synthesis

To a solution of 4-aminophenol (1 g, 9.2 mmol) in DMF (20 mL) was added 1M potassium ier/-butoxide in THF (9.7 mL, 9.7 mmol) at room temperature. After 2h, (4-chloro(2-pyridyl))-N- methyl carboxamide (1.6 g, 9.2 mmol) and potassium carbonate (0.64 g, 4.6 mmol) were added, and then the reaction mixture was heated to 80 °C for 6h. After cooling, the reaction mixture was extracted with ethyl acetate (50 mL). The organic layer was washed with brine (20 mL) and dried over magnesium sulfate. The solvent was removed in vacuo. The residue was purified by column chromatography to afford 4-(4-Aminophenoxy)-N-methylpicolinamide (2.2 g, 80 %) as a light-brown solid.

4-(4-Aminophenoxy)-N-methylpicolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-(4-Aminophenoxy)-N-methylpicolinamide Suppliers

Americas 1 Canada 1 China 340 Europe 1 Germany 1 India 56 Japan 2 Russia 1 Switzerland 1 United Kingdom 5 United States 20 Global 429
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
P C Chem
Tel
--
Fax
--
Email
info@pcchemindia.in
Country
India
ProdList
675
Advantage
58
Manus Aktteva Biopharma LLP
Tel
--
Fax
--
Email
products@manusakttevabiopharma.in
Country
India
ProdList
275
Advantage
58
Delta Finochem Pvt., Ltd.
Tel
--
Fax
--
Email
deltafinochem@gmail.com
Country
India
ProdList
44
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
RVR Labs Private Limited
Tel
--
Fax
--
Country
India
ProdList
49
Advantage
58
Raising Sun Pharma
Tel
--
Fax
--
Email
info@raisingsunpharma.com
Country
India
ProdList
66
Advantage
58
SVK Laboratories Pvt Ltd
Tel
--
Fax
--
Email
info@svklaboratories.com
Country
India
ProdList
9
Advantage
58
Aspen Biopharma Labs Pvt Ltd
Tel
--
Fax
--
Email
info@aspenbiopharmalabs.com
Country
India
ProdList
52
Advantage
58
Manus Aktteva Biopharma LLP
Tel
--
Fax
--
Country
India
ProdList
655
Advantage
58
Ethachem
Tel
--
Fax
--
Email
ethachem@vsnl.com
Country
India
ProdList
106
Advantage
58
Santo Righello Pvt. Ltd
Tel
--
Fax
--
Email
marketing@santorighello.com
Country
India
ProdList
918
Advantage
58
Rivashaa Agrotech Biopharma Pvt. Ltd.
Tel
--
Fax
--
Email
source@rivashaa.com
Country
India
ProdList
986
Advantage
58
Trignokem International
Tel
--
Fax
--
Country
India
ProdList
110
Advantage
58
Basil Pharmaceuticals
Tel
--
Fax
--
Email
backoffice@basilpharmaceutical.com
Country
India
ProdList
53
Advantage
58
Trignokem International.
Tel
--
Fax
--
Email
ignokem@gmail.com
Country
India
ProdList
233
Advantage
58
Hrishabh Life Sciences
Tel
--
Fax
--
Email
info@hrishabhlife.com
Country
India
ProdList
158
Advantage
58
Opulent Pharma
Tel
--
Fax
--
Country
India
ProdList
810
Advantage
58
Erevna Pharma Private Limited
Tel
--
Fax
--
Email
info@erevnapharma.com
Country
India
ProdList
51
Advantage
58
S. R. Chemical Specialities
Tel
--
Fax
--
Country
India
ProdList
90
Advantage
58
Dhanvi Exim Services
Tel
--
Fax
--
Email
info@dhanviexim.com
Country
India
ProdList
204
Advantage
58
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Bizten Impex Private Limited.
Tel
--
Fax
--
Country
India
ProdList
109
Advantage
58
GMFC Labs Pvt. Ltd.
Tel
--
Fax
--
Email
vasu@gmfclabs.com
Country
India
ProdList
23
Advantage
58
Bizten Impex Private Limited
Tel
--
Fax
--
Country
India
ProdList
71
Advantage
58
Amino Organics
Tel
--
Fax
--
Country
India
ProdList
86
Advantage
58
Clearsynth Labs
Tel
--
Fax
--
Email
fo@clearsynth.com
Country
India
ProdList
3887
Advantage
58
Kkyemistry (india) Pvt., Ltd.
Tel
--
Fax
--
Email
marketing@kyemistryindia.com
Country
India
ProdList
163
Advantage
58
Ami Organics Limited.
Tel
--
Fax
--
Email
mail@amiorganics.com
Country
India
ProdList
119
Advantage
58
Arunodaya Pharma Pvt., Ltd.
Tel
--
Fax
--
Email
arunodayapharma@gmail.com
Country
India
ProdList
62
Advantage
58
Delta Finochem Private Limited
Tel
--
Fax
--
Country
India
ProdList
32
Advantage
58
AVIK PHARMACEUTICAL LIMITED
Tel
--
Fax
--
Email
kuldip@avikpharma.com
Country
India
ProdList
54
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
Modepro India Pvt. Ltd.
Tel
--
Fax
--
Email
info@modepro.com
Country
India
ProdList
36
Advantage
0
Glenfin Chemicals Pvt. Ltd.
Tel
--
Fax
--
Email
marketing@glenfinchemicals.com
Country
India
ProdList
30
Advantage
58
Taj Mahal Vision Chemicals Private Limited
Tel
--
Fax
--
Country
India
ProdList
206
Advantage
58
GM Fine Chemicals
Tel
--
Fax
--
Country
India
ProdList
15
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
KKyemistry (India) Pvt. Ltd.
Tel
--
Fax
--
Email
info@kyemistryindia.com
Country
India
ProdList
197
Advantage
50
VIVAN Life Sciences Pvt. Limited.
Tel
--
Fax
--
Email
info@vivanls.com
Country
India
ProdList
138
Advantage
50
Srini Chem
Tel
--
Fax
--
Email
info@srinichem.com
Country
India
ProdList
6
Advantage
50
Trignokem International
Tel
--
Fax
--
Email
info@trignokem.com
Country
India
ProdList
380
Advantage
50
More
Less

View Lastest Price from 4-(4-Aminophenoxy)-N-methylpicolinamide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-(4-Aminophenoxy)-N-methylpicolinamide 284462-37-9
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kg
Release date
2021-10-22
Nanjing Fred Technology Co., Ltd
Product
4-(4-aminophenoxy)-N-methyl-picolinamide 284462-37-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-26
Hebei Yanxi Chemical Co., Ltd.
Product
4-(4-Aminophenoxy)-N-methylpicolinamide 284462-37-9
Price
US $20.00-10.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
200ton
Release date
2023-03-13

284462-37-9, 4-(4-Aminophenoxy)-N-methylpicolinamideRelated Search:

Sorafenib Sorafenib Impurity 35 Sorafenib Impurity 43 1-(4-chloro-3-(trifluoromethyl)phenyl)urea Trimebutine maleate PYRIDINE-2-CARBOXAMIDE N,N-Dimethylformamide N-Methylformamide SORAFENIB N-OXIDE Sorafenib tosylate N-Methyl-4-chloropyridine-2-carboxamide 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine 1,4-Benzoquinoneimine Sorafenib related compound 10 4-HYDROXYPHENYLFORMAMIDE Sorafenib IMpurity Sorafenib related coMpound 8 Sorafenib Related Compound 21

  • 4-(4-aMiNApheNAxy)-N-MethylpicolinaMide
  • 4-(4-aMinophenoxy)-N-MethylpicolinaMide oxalate
  • N-Methyl-4-(4-aMinophenoxy)pyridine-2-carboxaMide
  • Sorafenib impurity A
  • Sorafenib Intermediate
  • Sorafenib Related Compound 23
  • Sorafen
  • Sorafenib Aminophenoxy Impurity
  • Sorafenib tosylate INT III
  • N-Methyl-4-(4-aminophenoxy)pyridine-2-carboxamide Sorafenib Intermediates II
  • 4-(4- aMinophenoxy)-N- Methyl-2- pyridineforMaMide
  • 4-(4-Aminophenyloxy)-N-methyl-2-pyridininecarboxamide
  • Sorafenib INT2
  • 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide oxalate
  • 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
  • 4-(4-Aminophenoxy)-N-methylpicolinamide
  • 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]anilin
  • 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]aniline
  • 4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide
  • [4-(4-Aminophenoxy-2-pyridyl)]
  • 4-(4-AMino-phenoxy)-pyridine-2-carboxylicacidMethylaMide
  • 4-(4-AMinophenoxy)-pyridine-2-carboxylic acid aMide
  • 4-(4-Aminophenoxy)-N-methylpicolimide
  • [4-(4-Aminophenoxy-2-pyridyl)]-2-methylcarboxamide
  • 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide &gt
  • 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-
  • 4-(2-N-METHYLCARBOMOYL)-4-PYRIDYLOXY)ANILINE
  • 4-(4-Aminophenoxy)-N-methylpicolinamide ISO 9001：2015 REACH
  • 4-(4-Aminophenoxy)-N-methylpicolinamide (Sorafenib Impurity)
  • SL-M2
  • 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide (IP2014)
  • 284462-37-9
  • C13H13N3O2C2H2O4
  • Sorafinib
  • Aromatics Compounds
  • Aromatics
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Sorafenib tosylate
  • 284462-37-9