Polyinosinic acid-polycytidylic acid

Product Name: Polyinosinic acid-polycytidylic acid
CAS No.: 24939-03-5
Chemical Name: Polyinosinic acid-polycytidylic acid
Synonyms: polyi:c;polyi-c;Poly-Na;poly(i+c);Poly I:Cr;nsc-120949;polycpolyi;poly(ri:rc);Polyinosinic;polyri:polyrc
CBNumber: CB3181814
Molecular Formula: C19H27N7O16P2
Formula Weight: 671.41
MOL File: 24939-03-5.mol

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Polyinosinic acid-polycytidylic acid Property

storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Water (Slightly)
form: Solid
color: White to Off-White
Water Solubility: Soluble to 3 mg/ml in water
Stability:: Hygroscopic
InChIKey: ACEVNMQDUCOKHT-WOQDZEJINA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,22,23,24,32,r|

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Safety

WGK Germany: 3
RTECS: TR0175000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H402Harmful to aquatic life

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 4287
Product name: Poly(I:C)
Packaging: 10
Price: $98
Updated: 2021/12/16

Tocris

Product number: 4287
Product name: Poly(I:C)
Packaging: 50
Price: $410
Updated: 2021/12/16

TRC

Product number: P688075
Product name: Poly(I:C)(~90%)
Packaging: 50mg
Price: $65
Updated: 2021/12/16

TRC

Product number: P688075
Product name: Poly(I:C)(~90%)
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OP29952
Product name: Polyinosinic acid, homopolymer, complex with polycytidylic acid, homopolymer (1:1)
Packaging: 1g
Price: $80
Updated: 2021/12/16

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Polyinosinic acid-polycytidylic acid Chemical Properties,Usage,Production

Uses

Poly(I:C) is a toll-like receptor 3 dsRNA inflammatory stimulant.

Definition

ChEBI: A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.

Biological Activity

poly (i:c), a synthetic double-stranded rna (dsrna) analog, is an immunostimulant that acts as the most potent interferon (ifn) inducer. toll-like receptor- 3 (tlr3) agonist[1].mixtures that included the tlr7/8 agonists r848 or cl075, combined with the poly (i:c), yield 3-d mature dendritic cells [2].commonly used to stimulate immune system activation in vivo. also promotes maturation of hpsc-derived cardiomyocytes[3].[1]. li y g, siripanyaphinyo u, tumkosit u, et al. poly (i:c), an agonist of toll-like receptor-3, inhibits replication of the chikungunya virus in beas-2b cells. virology journal, 2012, 9(1): 114.[2]. spranger s, javorovic m, burdek m, et al. generation of th1-polarizing dendritic cells using the tlr7/8 agonist cl075. the journal of immunology, 2010, 185(1): 738-747.[3]. biermann m1, cai w2, lang d, et al. epigenetic priming of human pluripotent stem cell-derived cardiac progenitor cells accelerates cardiomyocyte maturation. stem cells, 2019, 37(7): 910-923.

Polyinosinic acid-polycytidylic acid Preparation Products And Raw materials

Raw materials

Yttrium oxide sulfate, terbium-doped Carbodiimide 5'—NUCLEOTIDE Cytidine 5’-monophosphate TAQ DNA POLYMERASE 5U/UL Creatine Microcrystalline cellulose Tributylamine Ribonucleic acid Sodium nitrite Agar Anhydrous pyridine Inosinic Acid Epichlorohydrin SULFATE STANDARD POLYNUCLEOTIDE PHOSPHORYLASE FROM BACIL Morpholine Ammonium sulfate

Preparation Products

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Polyinosinic acid-polycytidylic acid Suppliers

Canada 1 China 226 Germany 1 Switzerland 1 United Kingdom 2 United States 15 Global 246

Hubei widely chemical technology Co., Ltd.

Tel: 027-83778895 18602735115
Fax: 027-51119224
Email: 18602735115@163.com
Country: China
ProdList: 2000
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Taizhou DongBang Fine Chemical Co. Ltd.

Tel: 0523-86235448 15996000437
Fax: 0523-86235448
Email: 2535251509@qq.com
Country: China
ProdList: 49
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Hangzhou Weitai Biological Pharmaceutical Co., Ltd.

Tel: 86-571-82358004 13588879771
Email: sales1@weitai-pharmaceutical.com
Country: China
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Suzhou Tianhong Medicine Chemical Technology Co.,Ltd.

Tel: 18949937116
Email: dongye.huaxue@126.com
Country: China
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
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Wuhan Wei Shunda Technology Development Co., Ltd.

Tel: 86-027-88774375
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Email: mwmwhot@163.com
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XiaoGan ShenYuan ChemPharm co,ltd

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Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
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Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
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ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3203
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View Lastest Price from Polyinosinic acid-polycytidylic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Polycytidylic Acid 24939-03-5
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-21

Hebei Weibang Biotechnology Co., Ltd

Product: Polyinosinic-polycytidylic acid sodium salt 24939-03-5
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-05

Hebei Chuanghai Biotechnology Co,.LTD

Product: Polyinosinic acid-polycytidylic acid 24939-03-5
Price: US $10.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-21

24939-03-5, Polyinosinic acid-polycytidylic acidRelated Search:

Glycine Folic acid Ethyl 2-(Chlorosulfonyl)acetate Cytidine 5’-monophosphate L-DIHYDROOROTIC ACID Cytidine-5'-triphosphate disodium salt dihydrate Citric acid 5-Azacytidine Cytarabine Ascoric Acid N-BUTYLISOCYANIDE Cupric acetylacetonate TERT-BUTYL ISOCYANIDE Tosylmethyl isocyanide Aluminum acetylacetonate Inosinic Acid 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Ethyl isocyanoacetate

POLY(I) POLY(C)

POLYINOSINIC ACID POLYCYTIDYLIC ACID

POLYINOSINIC POLYCYTIDYLIC ACID

polyinosinic:polycytidylic acid copolymer

POLYCYTIDYLIC-INOSINIC ACID

Polyinosinic-polytidylin Acid.

POLYINOSINIC ACID . POLYCYTIDYLIC ACID, LYOPHILIZED

POLYCYTIDYLIC-INOSINIC ACID POTASSIUM

Polyinosinic

Polyinosinic Polycytidylic

POLYINOSINIC-POLYCYTIDILICACIDKSALT

Poly inosine-cytidine

5’-inosinicacid,homopolymer,complexwith5’-cytidylicacidhomopolymer(1:

5’-Inosinicacid,homopolymer,complexwith5’-cytidylicacidhomopolymer(1:1)

polyi:c

polyi-c

polyri:polyrc

Polycytidysic acid (Poly C)

Polyinosinic acid-po

nsc-120949

poly(i).poly(c)complex

poly(i+c)

poly(ri).(rc)

poly(ri).poly(rc)

poly(ri:rc)

polycpolyi

polycytidylic-polyinosinicacid

Polyinosinic-cytidylic acid disodiuM salt

Poly(I:C) (~90%)

Polyinosinic acid: polycytidylic acid (poly I:C)

Polyinosinic acid-polycytidylic acid USP/EP/BP

Poly I:Cr

Polyadenosinic acid sodium salt，Poly A

Poly-Na

Polyinosinic-polycytidylic acid sodium salt (PIC)

CID 135618150

[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate

Glycine Impurity 24

24939-03-5

C10H11N4O7PnC9H12N3O7PnC38H50

C10H13N4O8PC9H14N3O8P

C19H27N7O16P2

C10H13N4O8PxC9H14N3O8Px

Nucleosides, Nucleotides, Oligonucleotides

Synthetic Oligonucleotides and Related Reagents

Biochemicals and Reagents

BioChemical

Material