4-Cholesten-3-one

Product Name: 4-Cholesten-3-one
CAS No.: 601-57-0
Chemical Name: 4-Cholesten-3-one
Synonyms: CHOLESTENONE;4-Cholestenone;4-CHOLESTEN-3-ONE;3-Oxocholest-4-ene;3-OXO-4-CHOLESTENE;cholest-4-en-3-one;4-Cholestene-3-one;CHOLEST-4-ENE-3-ONE;3-KETO-4-CHOLESTENE;(+)-4-CHOLESTEN-3-ONE
CBNumber: CB3222827
Molecular Formula: C27H44O
Formula Weight: 384.64
MOL File: 601-57-0.mol

More

Less

4-Cholesten-3-one Property

Melting point:: 79-82 °C
alpha: 92.5 º (c=2, CHCl3)
Boiling point:: 451.27°C (rough estimate)
Density: 0.9717 (rough estimate)
refractive index: 1.5100 (estimate)
storage temp.: -20°C
solubility: Chloroform (Sparingly), Methanol (Slightly, Heated)
form: Solid
color: White to Off-White
optical activity: [α]23/D +91.0°, c = 2 in chloroform
Water Solubility: <0.5 g/L
BRN: 4707774
Stability:: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 601-57-0(CAS DataBase Reference)
NIST Chemistry Reference: Cholest-4-en-3-one(601-57-0)
EPA Substance Registry System: Cholest-4-en-3-one (601-57-0)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: FZ7700000
TSCA: Yes
HS Code: 29142900

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 188174
Product name: (+)-4-Cholesten-3-one
Purity: 98%
Packaging: 1g
Price: $33
Updated: 2024/03/01

Sigma-Aldrich

Product number: 188174
Product name: (+)-4-Cholesten-3-one
Purity: 98%
Packaging: 10g
Price: $313
Updated: 2024/03/01

Alfa Aesar

Product number: A11743
Product name: 4-Cholesten-3-one, 98+%
Packaging: 5g
Price: $71.65
Updated: 2024/03/01

Alfa Aesar

Product number: A11743
Product name: 4-Cholesten-3-one, 98+%
Packaging: 25g
Price: $253.65
Updated: 2024/03/01

Cayman Chemical

Product number: 25713
Product name: Cholestenone
Packaging: 5g
Price: $81
Updated: 2024/03/01

More

Less

4-Cholesten-3-one Chemical Properties,Usage,Production

Description

Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.

Chemical Properties

white to light yellow crystals or powder

Uses

4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.

Definition

ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.

General Description

Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.

4-Cholesten-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-Cholesten-3-one Suppliers

Belgium 2 China 104 Europe 1 Germany 8 India 14 Japan 2 Lithuania 1 Norway 1 Switzerland 5 The Netherlands 2 Ukraine 1 United Kingdom 20 United States 35 Global 196

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

MilliporeSigma (Sigma-Aldrich Corp.)

Tel: --
Fax: --
Email: @sial.com
Country: United States
ProdList: 5414
Advantage: 58

Chem-Impex International, Inc. (CII)

Tel: --
Fax: --
Email: Customer@chemimpex.com
Country: United States
ProdList: 893
Advantage: 58

TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)

Tel: --
Fax: --
Email: .Crew@tcichemicals.com
Country: United States
ProdList: 3164
Advantage: 58

MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)

Tel: --
Fax: --
Email: serv@mpbio.com
Country: United States
ProdList: 1854
Advantage: 58

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United States
ProdList: 4583
Advantage: 58

Spectrum Chemical Mfg. Corp.

Tel: --
Fax: --
Email: marketing@spectrumchemical.com
Country: United States
ProdList: 3113
Advantage: 60

VWR International, LLC.

Tel: --
Fax: --
Email: @sargentwelch.com
Country: United States
ProdList: 6262
Advantage: 58

Research Plus Inc.

Tel: --
Fax: --
Country: United States
ProdList: 35
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Anisyn, Inc.

Tel: --
Fax: --
Email: sales@anisyn.com
Country: United States
ProdList: 863
Advantage: 0

Cambridge Isotope Laboratories, Inc.

Tel: --
Fax: --
Email: cilsales@isotope.com
Country: United States
ProdList: 6598
Advantage: 79

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

ECA International Corporation

Tel: --
Fax: --
Email: services@ecacorporation.com
Country: United States
ProdList: 1062
Advantage: 52

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Advance Scientific & Chemical

Tel: --
Fax: --
Email: sales@advance-scientific.com
Country: United States
ProdList: 6419
Advantage: 71

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

ChromaDex

Tel: --
Fax: --
Email: sales@chromadex.com
Country: United States
ProdList: 2501
Advantage: 76

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

Research Plus, Inc.

Tel: --
Fax: --
Email: respls@aol.com
Country: United States
ProdList: 3674
Advantage: 51

Steraloids Inc.

Tel: --
Fax: --
Email: sales@steraloids.com
Country: United States
ProdList: 2357
Advantage: 68

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

Avanti Polar Lipids, Inc.

Tel: --
Fax: --
Email: info@avantilipids.com
Country: United States
ProdList: 610
Advantage: 79

Fisher Scientific

Tel: --
Fax: --
Email: sales@fishersci.com
Country: United States
ProdList: 2337
Advantage: 86

More

Less

View Lastest Price from 4-Cholesten-3-one manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Cholesten-3-one 601-57-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Cholesten-3-one 601-57-0
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-03

Hebei Mujin Biotechnology Co.,Ltd

Product: 4-Cholesten-3-one 601-57-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-10

601-57-0, 4-Cholesten-3-oneRelated Search:

Dimethyl sulfoxide Trenbolone 6-Methyl-5-hepten-2-one ETHANE Quinocetone Zearalenone 2-Cyclohexen-1-one Dimethyl sulfide Dimethyl carbonate Dimethyl fumarate Clethodim Dacthal Dimethyl sulfate Dimethyl sebacate N,N-Dimethylformamide Androstenedione Dimethyl ether 2BETA,3BETA,14ALPHA,22[R],25-PENTAHYDROXY-7-CHOLESTEN-6-ONE,2β,3β,14α,22(r),25-pentahydroxy-7-cholesten-6-one

17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah

17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE

(+)-4-CHOLESTEN-3-ONE

4-CHOLESTEN-3-ONE

3-KETO-4-CHOLESTENE

(+)-3-OXO-4-CHOLESTENE

3-OXO-4-CHOLESTENE

CHOLEST-4-ENE-3-ONE

CHOLESTENONE

3-Oxocholest-4-ene

4-Cholestenone

cholest-4-en-3-one

delta4-Cholesten-3-one

(8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

4-CHOLESTEN-3-ONE, 98+%

(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

3-Keto-4-cholestene, 3-Oxo-4-cholestene

3-Keto-4-cholestene, 3-Oxo-4-cholestene, 4-Cholesten-3-one

delta(sup 4)-Cholestenone

(20R)-Cholesta-4-ene-3-one

Cholestane-4-ene-3-one

(8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

(+)-4-Cholesten-3-one 98%

4-CHOLESTEN-3-ONE;CHOLESTENONE

(1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

4-Cholestene-3-one

(+)-4-Cholesten-3-one &gt

(+)-4-Cholesten-3-one

(+)-3-Oxo-4-Cholestene

601-57-0

Complex Molecules

Chiral Building Blocks

Asymmetric Synthesis

Steroids

Steroids (Others)

Steroids

Steroids (Others)

Biochemistry