2-Dimethylaminoisopropyl chloride hydrochloride

Product Name: 2-Dimethylaminoisopropyl chloride hydrochloride
CAS No.: 4584-49-0
Chemical Name: 2-Dimethylaminoisopropyl chloride hydrochloride
Synonyms: DMIC;2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL;1-(DIMETHYLAMINO)-2-CHLOROPROPANE HYDROCHLORIDE;B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE;2-DMPC;2-DMPC 99%;DMIC 99%min;Lipoic acid 62-46-4;2-Dimethylaminoisopropyl;intermediate of Methadone
CBNumber: CB3235881
Molecular Formula: C5H13Cl2N
Formula Weight: 158.07
MOL File: 4584-49-0.mol

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2-Dimethylaminoisopropyl chloride hydrochloride Property

Melting point:: 187-190 °C(lit.)
storage temp.: Store below +30°C.
solubility: 2000g/l
form: Crystalline Powder
color: White to light cream
PH: 5-6 (500g/l, H2O, 20℃)
Water Solubility: 2000 g/L (20 º C)
Sensitive: Hygroscopic
BRN: 3670215
InChI: InChI=1S/C5H12ClN.ClH/c1-5(6)4-7(2)3;/h5H,4H2,1-3H3;1H
InChIKey: OCWGRWAYARCRTQ-UHFFFAOYSA-N
SMILES: C(Cl)(C)CN(C)C.Cl
CAS DataBase Reference: 4584-49-0(CAS DataBase Reference)
EPA Substance Registry System: 2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RIDADR: 2811
WGK Germany: 3
RTECS: TY1225000
TSCA: Yes
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29211980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D142409
Product name: 2-Chloro-N,N-dimethylpropylamine hydrochloride
Purity: 98%
Packaging: 100g
Price: $33.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.03240
Product name: N-(2-Chloropropyl)-N,N-dimethylammonium chloride
Purity: for synthesis
Packaging: 250G
Price: $95.6
Updated: 2024/03/01

TCI Chemical

Product number: D1665
Product name: 2-Chloro-1-(dimethylamino)propane Hydrochloride
Purity: >98.0%(T)
Packaging: 25g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: D1665
Product name: 2-Chloro-1-(dimethylamino)propane Hydrochloride
Purity: >98.0%(T)
Packaging: 500g
Price: $279
Updated: 2024/03/01

Alfa Aesar

Product number: B20882
Product name: 2-Dimethylaminoisopropyl chloride hydrochloride, 98%
Packaging: 500g
Price: $97.2
Updated: 2023/06/20

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2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Colourless to pale beige crystalline powder

Uses

2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl, methadone and promethazine)

Uses

Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.

General Description

Off-white chunky solid.

Air & Water Reactions

2-Dimethylaminoisopropyl chloride hydrochloride is hygroscopic. Soluble in water.

Reactivity Profile

2-Dimethylaminoisopropyl chloride hydrochloride is incompatible with strong oxidizing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 2-Dimethylaminoisopropyl chloride hydrochloride are not available; however, 2-Dimethylaminoisopropyl chloride hydrochloride is probably combustible.

Synthesis

Following the procedure of Schultz and Sprague, J. Am. Chem. Soc., 70, 48 (1948), a solution containing 3.77 g. of 1-dimethylamino-2-propanol and 10 ml. of chloroform was cooled with stirring to a temperature of about 0?? C. A solution of 5.72 g. of freshly distilled thionylchloride in 2 ml. of chloroform was added thereto. The reaction mixture was allowed to come to ambient temperature over a period of about 30 minutes and was then heated to refluxing temperature for an additional 30 minutes. The precipitated material redissolved on heating. 1-Dimethylamino-2-chloropropane hydrochloride began to crystallize from the boiling solvent. The reaction mixture was cooled, diluted with ether and filtered. The reaction product comprising 1-dimethylamino-2-chloropropane hydrochloride weighed about 5.5 g. (95 percent yield). Recrystallization yielded purified 1-dimethylamino-2-chloropropane hydrochloride melting at 192??-194?? C.

2-Dimethylaminoisopropyl chloride hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Dimethylaminoisopropyl chloride hydrochloride Suppliers

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View Lastest Price from 2-Dimethylaminoisopropyl chloride hydrochloride manufacturers

Dorne Chemical Technology co. LTD

Product: 2-DMPC 4584-49-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2024-05-25

Jinan Finer Chemical Co., Ltd

Product: 2-Dimethylaminoisopropyl chloride hydrochloride 4584-49-0
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%
Supply Ability: 100mt
Release date: 2020-11-05

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 2-Dimethylaminoisopropyl chloride hydrochloride 4584-49-0
Price: US $100.00-70.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-16

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DMIC

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BETA-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE

B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE

N-(2-CHLORO-PROPYL)DIMETHYLAMINE

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2-CHLORO-N,N-DIMETHYLPROPYLAMINE HCL

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2-Dimethylaminoisopropyl chloride hydrochloride, 98.50%

2-chloro-N,N-dimethylpropan-1-amine hydrochloride

2-Dimethylaminoisopropyl

1-Propanamine, 2-chloro-N,N-dimethyl-, hydrochloride

2-Chloro-N,N-dimethylpropylamine hydrochloride 98%

Dimethylamino-2-propyl chloride hydrochloride

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DMIC 99%min

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99%min, intermediate of Methadone HCL

intermediate of Methadone

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2-Dimethylaminoisopropyl chloride hydrochloride ISO 9001：2015 REACH

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Certified Product 2-Dimethylaminoisopropyl chloride hydrochloride CAS 4584-49-0

Lipoic acid 62-46-4