Tubacin

Product Name: Tubacin
CAS No.: 537049-40-4
Chemical Name: Tubacin
Synonyms: Tubacin;BML-GR362;4R,6S)N8-[(2R,dioxan-Tubacin, >=98%;diphenyl-oxazolyl)
CBNumber: CB32519138
Molecular Formula: C41H43N3O7S
Formula Weight: 721.86
MOL File: 537049-40-4.mol

More

Less

Tubacin Property

Melting point:: 155 - 157°C
storage temp.: -20°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to tan

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0065
Product name: Tubacin
Purity: ≥98% (HPLC)
Packaging: 1mg
Price: $239
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0065
Product name: Tubacin
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $631
Updated: 2024/03/01

Cayman Chemical

Product number: 13691
Product name: Tubacin
Purity: ≥90%
Packaging: 1mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 13691
Product name: Tubacin
Purity: ≥90%
Packaging: 5mg
Price: $336
Updated: 2024/03/01

Tocris

Product number: 3402
Product name: Tubacin
Purity: ≥96%(HPLC)
Packaging: 1
Price: $287
Updated: 2021/12/16

More

Less

Tubacin Chemical Properties,Usage,Production

Uses

Tubacin is tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC6).

Definition

ChEBI: N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide is a member of 1,3-oxazoles.

Biochem/physiol Actions

Tubacin triggers the release of reactive oxygen species and mediates caspase-3-independent apoptosis of Epstein-Barr virus (EBV)-positive Burkitt lymphoma cells. It suppresses the proliferation of acute lymphoblastic leukemia (ALL) cells and enhances the effect of chemotherapy to treat ALL cells. Tubacin prevents the epileptic activity and neuronal migration defects caused due to lowered expression of Srpx2 in rats.

target

HDAC6

Tubacin Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tubacin Suppliers

China 69 India 2 United States 13 Global 84

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Accendatech Co., LTD.

Tel: 022-83718541 022-83718543
Fax: 022-83718543-802
Email: chuanjiang.qiu@accendatech.com
Country: China
ProdList: 332
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: +86 (21) 5895-8628
Email: SALES@UHNSHANGHAI.COM
Country: China
ProdList: 977
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9798
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9767
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9972
Advantage: 58

537049-40-4, TubacinRelated Search:

1H-Benz[de]isoquinoline-2(3H)-butanamide SCRIPTAID SPLITOMICIN Sodium 4-phenylbutyrate BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE APICIDIN CAY10603 OXAMFLATIN Entinostat HC TOXIN M344 Parthenolide ACY-1215 TRICHOSTATIN A Tacedinaline Nexturastat A Mocetinostat (MGCD0103) Tubastatin-A

Tubacin

N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

Tubacin, >=98%

BML-GR362

N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di

Tubacin (BML-GR362)

Octanediamide, N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-, rel-

Octanediamide,N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxy-, rel-

Tubacin (tubulin acetylation inducer)

rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide

Tubacin,Inhibitor,HDAC,Virus Protease,inhibit,Histone deacetylases

(hydroxymethyl)&#8203

[(2R,&#8203

4R,&#8203

6S)&#8203

dioxan-&#8203

diphenyl-&#8203

N8-&#8203

Octanediamide, N1-&#8203

oxazolyl)&#8203

537049-40-4

C41H43N3O7S

Inhibitors